IRF1 and NPM1

  • Number of citations of the paper that reports this interaction (PMID 21245151)
  • 7
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)

IRF1

NPM1

Gene Name interferon regulatory factor 1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 23 interactors: CDKN1B CREBBP EP300 HMGA1 IRF2 IRF8 IRF9 KAT2A KAT2B KEAP1 MDM2 NFKB1 NPM1 QARS RELA SET SPI1 STAT1 STUB1 TRAF3 TRIM28 UBC YBX1 53 interactors: ABCC1 ACY1 ALK APP ARF1 CDK1 CDK2 CDKN1A CDT1 COX8A CSNK2A1 EIF2AK2 EIF3E ELF4 EP300 ERG GADD45A GNAI2 GRB2 GZMM HAND2 HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE HIST3H3 HMGA1 HMGA2 HOXA7 IRF1 IRS1 MDM2 NCL NOP2 NPM2 PADI4 PARP1 PLCG1 PLCG2 PLK1 PSMC4 RELA RPGR SENP3 SHC1 SREK1 TCERG1 TFAP2A TP53 UQCRH USP36 XPO1 YY1
Entrez ID 3659 4869
HPRD ID 00961 01246
Ensembl ID ENSG00000125347 ENSG00000181163
Uniprot IDs P10914 Q6FHN8 P06748
PDB IDs 2LLH 2P1B 2VXD
Enriched GO Terms of Interacting Partners?
Tagcloud ?
activating  activators  architectural  assembled  assembly  atf2  cbp  coactivator  consisting  context  decreases  deletion  designated  domains  enhanceosome  generated  hmg  jun  kappa  p65  phenomenon  rearrangement  recruitment  requires  substitution  sum  synergy  transcriptional  y 
aggressive  aml  amplicon  consecutive  counterparts  covering  de  expands  flt3  frequent  heterogeneous  hotspots  illumina  mds  mutated  myeloid  neoplasms  next  novo  panel  prevalent  profile  profiling  ptpn11  similarly  summary  syndromes  tp53  truseq 
Tagcloud (Difference) ?
activating  activators  architectural  assembled  assembly  atf2  cbp  coactivator  consisting  context  decreases  deletion  designated  domains  enhanceosome  generated  hmg  jun  kappa  p65  phenomenon  rearrangement  recruitment  requires  substitution  sum  synergy  transcriptional  y 
aggressive  aml  amplicon  consecutive  counterparts  covering  de  expands  flt3  frequent  heterogeneous  hotspots  illumina  mds  mutated  myeloid  neoplasms  next  novo  panel  prevalent  profile  profiling  ptpn11  similarly  summary  syndromes  tp53  truseq 
Tagcloud (Intersection) ?