TLR4 and SIGIRR

  • Number of citations of the paper that reports this interaction (PMID 12925853)
  • 92
  • Data Source:
  • HPRD (in vivo)

TLR4

SIGIRR

Gene Name toll-like receptor 4 single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 24 interactors: BCL10 BTK CD14 CNPY4 DEFB4A HMGB1 HSP90B1 IRAK1 IRAK2 LY96 MAPK8IP3 MYD88 NOX4 RIPK2 RNF216 SERTAD1 SIGIRR SMAD3 SYK TICAM2 TIRAP TLR1 TLR5 TOLLIP 9 interactors: APP ENO2 IL1R1 IRAK1 RPN1 TLR4 TLR5 TLR9 TRAF6
Entrez ID 7099 59307
HPRD ID 04325 12018
Ensembl ID ENSG00000136869 ENSG00000185187
Uniprot IDs O00206 C9JFX4 Q6IA17
PDB IDs 2Z62 2Z63 2Z65 2Z66 3FXI 3UL7 3UL8 3UL9 3ULA 4G8A
Enriched GO Terms of Interacting Partners?
Tagcloud ?
bed  cd14  constitutively  fibroblast  immunoassay  immunocytochemistry  lamina  lipopolysaccharide  lps  md  measuring  microorganisms  nucleus  p65  polyp  propria  quantified  respond  responsiveness  scar  strategic  supernatant  tlr1  tlr9  tlrs  toll  vff  vffs  vocal 
1r  acting  affects  autoimmune  c3  c4  cd4  circulating  correlation  cytometer  erythematosus  esr  explored  glucocorticoid  hour  immunoglobulin  lupus  mononuclear  nephritis  pbmcs  percentages  quantified  scr  sle  sledai  summary  tlr  z 
Tagcloud (Difference) ?
bed  cd14  constitutively  fibroblast  immunoassay  immunocytochemistry  lamina  lipopolysaccharide  lps  md  measuring  microorganisms  nucleus  p65  polyp  propria  respond  responsiveness  scar  strategic  supernatant  tlr1  tlr9  tlrs  toll  vff  vffs  vocal 
1r  acting  affects  autoimmune  c3  c4  cd4  circulating  correlation  cytometer  erythematosus  esr  explored  glucocorticoid  hour  immunoglobulin  lupus  mononuclear  nephritis  pbmcs  percentages  scr  sle  sledai  summary  tlr  z 
Tagcloud (Intersection) ?
quantified