IMPA1 and NXF1

Number of citations of the paper that reports this interaction (PMID 21965294)
4

Data Source:
BioGRID (pull down, pull down)

		IMPA1	NXF1
Gene Name		inositol(myo)-1(or 4)-monophosphatase 1	nuclear RNA export factor 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Vesicular Exosome	Transcription Export Complex Nuclear Pore Nucleoplasm Cytosol Nuclear Speck Nuclear Inclusion Body
	Molecular Function	Magnesium Ion Binding Inositol Monophosphate 1-phosphatase Activity Manganese Ion Binding Lithium Ion Binding Identical Protein Binding Protein Homodimerization Activity Inositol Monophosphate 3-phosphatase Activity Inositol Monophosphate 4-phosphatase Activity Inositol Monophosphate Phosphatase Activity	Nucleotide Binding MRNA Binding Nucleocytoplasmic Transporter Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Inositol Biosynthetic Process Phosphatidylinositol Biosynthetic Process Phosphate-containing Compound Metabolic Process Signal Transduction Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation Inositol Phosphate Dephosphorylation	MRNA Export From Nucleus Gene Expression Viral Process Poly(A)+ MRNA Export From Nucleus
Pathways		Synthesis of IP2, IP, and Ins in the cytosol Inositol phosphate metabolism	Transport of Mature mRNA Derived from an Intronless Transcript Processing of Capped Intron-Containing Pre-mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA derived from an Intron-Containing Transcript Transport of Mature mRNAs Derived from Intronless Transcripts Transport of the SLBP independent Mature mRNA Transport of Mature Transcript to Cytoplasm
Drugs		Lithium L-Myo-Inositol-1-Phosphate
Diseases
GWAS		Ovarian cancer ( 23535730)
Protein-Protein Interactions		4 interactors: CALB1 IMPA2 NXF1 S100B	51 interactors: ALYREF CSNK2A1 DHX9 DVL3 EIF4A3 ELAVL4 ESRRA GFAP HNRNPUL1 IMPA1 IPO11 IPO4 KCTD5 KRT40 LDOC1 MAGOH MAP1A MAP1B MID2 NUP153 NUP214 NUP62 NUP98 NXF2 NXF3 NXF5 NXT1 NXT2 RAD51 RAE1 RAN RANBP2 RBM15B RBM8A SGTA SH2D3A SRSF1 SRSF3 SRSF7 STRAP THOC5 TIFA TNPO1 TNPO2 TRA2A TRA2B U2AF1 UBQLN4 UPF3A XIST ZBED2
Entrez ID		3612	10482
HPRD ID		03641	04035
Ensembl ID		ENSG00000133731	ENSG00000162231
Uniprot IDs		P29218	Q59E96 Q9UBU9
PDB IDs		1AWB 1IMA 1IMB 1IMC 1IMD 1IME 1IMF 2HHM 4AS4	1FO1 1FT8 1GO5 1JKG 1JN5 1KOH 1KOO 1OAI 2Z5K 2Z5M 3RW6 3RW7
Enriched GO Terms of Interacting Partners?		Memory Metanephric Connecting Tubule Development Regulation Of Synaptic Plasticity Negative Regulation Of Skeletal Muscle Cell Differentiation Metanephric Part Of Ureteric Bud Development Learning Or Memory Cognition Metanephric Distal Convoluted Tubule Development Regulation Of Synaptic Transmission Metanephric Distal Tubule Development Inositol Biosynthetic Process Poly(A)+ MRNA Export From Nucleus Response To Methylmercury Metanephric Collecting Duct Development Distal Tubule Development Inositol Phosphate Dephosphorylation Phosphorylated Carbohydrate Dephosphorylation Single-organism Behavior Collecting Duct Development Short-term Memory Metanephric Nephron Tubule Development Regulation Of Skeletal Muscle Cell Differentiation Negative Regulation Of Skeletal Muscle Tissue Development Behavior Inositol Metabolic Process Retina Layer Formation Metanephric Epithelium Development Metanephros Morphogenesis Astrocyte Differentiation Long-term Memory Negative Regulation Of Striated Muscle Tissue Development Long-term Synaptic Potentiation Inositol Phosphate Metabolic Process Negative Regulation Of Muscle Organ Development Alcohol Catabolic Process Neural Retina Development Retina Morphogenesis In Camera-type Eye Regulation Of Neuronal Synaptic Plasticity MRNA Export From Nucleus Regulation Of Skeletal Muscle Tissue Development	RNA Transport RNA Localization MRNA Transport Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus Nuclear Export MRNA Export From Nucleus Cytoplasmic Transport Intracellular Transport MRNA Processing RNA Splicing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Establishment Of Localization In Cell RNA Processing Gene Expression Cellular Localization Termination Of RNA Polymerase II Transcription MRNA 3'-end Processing Viral Process RNA 3'-end Processing Mitotic Nuclear Envelope Disassembly DNA-templated Transcription, Termination Viral Life Cycle RNA Metabolic Process Nuclear Envelope Disassembly Regulation Of MRNA Splicing, Via Spliceosome Nuclear Import Nuclear Envelope Organization Glucose Transport Nucleobase-containing Compound Metabolic Process Hexose Transport Regulation Of MRNA Processing Viral Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Glucose Transport Regulation Of RNA Splicing Transport Cellular Nitrogen Compound Metabolic Process Protein Import Into Nucleus Nucleus Organization Carbohydrate Transport Intracellular Transport Of Virus Regulation Of Alternative MRNA Splicing, Via Spliceosome Protein Import Nitrogen Compound Metabolic Process Protein Localization To Nucleus
Tagcloud ?			betaretrovirus cte gag gammaretroviral gammaretrovirus gammaretroviruses isogenic lentiviruses license mason mlv mpmv nxt pfizer pol polyprotein polyribosomes polysome polysomes pr65gag quantitated retrovirus retroviruses shuttling srp20 synergized synthesize unspliced xmrv
Tagcloud (Difference) ?			betaretrovirus cte gag gammaretroviral gammaretrovirus gammaretroviruses isogenic lentiviruses license mason mlv mpmv nxt pfizer pol polyprotein polyribosomes polysome polysomes pr65gag quantitated retrovirus retroviruses shuttling srp20 synergized synthesize unspliced xmrv
Tagcloud (Intersection) ?