IL10RA and TMEM242

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IL10RA	TMEM242
Description		interleukin 10 receptor subunit alpha	transmembrane protein 242
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cilium Membrane Apical Plasma Membrane	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding Signaling Receptor Activity	Protein Binding
	Biological Process	Negative Regulation Of Autophagy Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Inflammatory Response Regulation Of Synapse Organization Intestinal Epithelial Structure Maintenance Ubiquitin-dependent Endocytosis Interleukin-10-mediated Signaling Pathway	Mitochondrial Proton-transporting ATP Synthase Complex Assembly
Pathways		Interleukin-10 signaling Nuclear events stimulated by ALK signaling in cancer
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Ankle-brachial index ( 31388106) General risk tolerance (MTAG) ( 30643258) Lipoprotein (a) levels ( 26377243)
Interacting Genes		20 interacting genes: BTRC C1QL4 CDS2 CMTM3 HACD1 IL10 IL10RB JAK1 MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6	36 interacting genes: AQP6 ATP6V0B BCL2L13 CNR2 CYB561 EBP ELOVL4 GGT7 GHITM GJA8 GOLT1A GPR42 GRINA HSD17B11 IL10RA JAGN1 MFSD2A MFSD6 MSMO1 MTIF3 NDUFA3 PLP1 RNF5 SGPL1 SLC10A1 SLC10A6 SLC19A3 SLC29A2 SLC30A3 SYNJ2BP TMBIM1 TMEM179B TMEM31 TMEM51 TMIE VKORC1
Entrez ID		3587	729515
HPRD ID		00911
Ensembl ID		ENSG00000110324	ENSG00000215712
Uniprot IDs		Q13651	Q9NWH2
PDB IDs		1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI 6X93
Enriched GO Terms of Interacting Partners?		Interleukin-10-mediated Signaling Pathway Membrane Response To Inactivity Type III Interferon-mediated Signaling Pathway	Membrane Transmembrane Transport Endoplasmic Reticulum Bile Acid:sodium Symporter Activity Monoatomic Ion Transport Lipid Biosynthetic Process Monoatomic Cation Transport Inorganic Cation Transmembrane Transport Endoplasmic Reticulum Membrane Small Molecule Biosynthetic Process Pyrimidine-containing Compound Transmembrane Transport Inorganic Ion Transmembrane Transport Monoatomic Ion Transmembrane Transport Calcium Channel Activity Steroid Biosynthetic Process Bile Acid And Bile Salt Transport
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