TMEM242 and CYB561

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM242	CYB561
Description		transmembrane protein 242	cytochrome b561
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane	Lysosomal Membrane Membrane Cytoplasmic Vesicle Chromaffin Granule Membrane
	Molecular Function	Protein Binding	Protein Binding Oxidoreductase Activity Metal Ion Binding Transmembrane Monodehydroascorbate Reductase Activity
	Biological Process	Mitochondrial Proton-transporting ATP Synthase Complex Assembly	Intracellular Iron Ion Homeostasis Electron Transport Chain Ascorbate Homeostasis
Pathways
Drugs
Diseases
GWAS		Ankle-brachial index ( 31388106) General risk tolerance (MTAG) ( 30643258) Lipoprotein (a) levels ( 26377243)	Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Diastolic blood pressure ( 28739976)
Interacting Genes		36 interacting genes: AQP6 ATP6V0B BCL2L13 CNR2 CYB561 EBP ELOVL4 GGT7 GHITM GJA8 GOLT1A GPR42 GRINA HSD17B11 IL10RA JAGN1 MFSD2A MFSD6 MSMO1 MTIF3 NDUFA3 PLP1 RNF5 SGPL1 SLC10A1 SLC10A6 SLC19A3 SLC29A2 SLC30A3 SYNJ2BP TMBIM1 TMEM179B TMEM31 TMEM51 TMIE VKORC1	60 interacting genes: ANKRD46 AQP6 BEST2 BET1 BIK BNIP1 CD79A CDIPT CLDN9 CMTM2 CREB3 DARS2 EBP EDA EFNA5 EHHADH ERG28 ERGIC3 FAM209A FKBP8 GGT7 GIMAP5 GOSR2 GPR152 GPX8 HMOX1 LHFPL5 LMNA LPAR3 OPRM1 ORMDL2 PLP2 REEP6 RNF5 SCD SEC22A SERP2 SLC19A3 SLC35H1 SLC38A7 SLC39A1 SLC39A2 SMIM1 SSMEM1 STX3 SYNJ2BP TM4SF18 TMEM11 TMEM128 TMEM14B TMEM179B TMEM242 TMEM65 TMPPE TREX1 TSNARE1 UBE2J1 VAPA VAPB ZDHHC7
Entrez ID		729515	1534
HPRD ID			02485
Ensembl ID		ENSG00000215712	ENSG00000008283
Uniprot IDs		Q9NWH2	B3KTA1 J3QRH5 P49447
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Endoplasmic Reticulum Bile Acid:sodium Symporter Activity Monoatomic Ion Transport Lipid Biosynthetic Process Monoatomic Cation Transport Inorganic Cation Transmembrane Transport Endoplasmic Reticulum Membrane Small Molecule Biosynthetic Process Pyrimidine-containing Compound Transmembrane Transport Inorganic Ion Transmembrane Transport Monoatomic Ion Transmembrane Transport Calcium Channel Activity Steroid Biosynthetic Process Bile Acid And Bile Salt Transport	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity SNARE Complex Membrane Fusion Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Binding Organelle Membrane Fusion FFAT Motif Binding Mitochondrial Membrane Golgi Vesicle Transport Endoplasmic Reticulum Organization Membrane Organization Organelle Fusion COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Organelle Localization By Membrane Tethering Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum Localization Membrane Docking Vesicle Fusion Lipid Biosynthetic Process Host-mediated Activation Of Viral Genome Replication Positive Regulation Of Collateral Sprouting Host-mediated Perturbation Of Viral Genome Replication Progesterone Receptor Signaling Pathway Vesicle Organization
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