TMEM242 and SLC29A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM242	SLC29A2
Description		transmembrane protein 242	solute carrier family 29 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane	Nucleolus Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding	Neurotransmitter Transmembrane Transporter Activity Nucleoside Transmembrane Transporter Activity Nucleobase Transmembrane Transporter Activity Adenine Transmembrane Transporter Activity Guanine Transmembrane Transporter Activity Uracil Transmembrane Transporter Activity Purine Nucleoside Transmembrane Transporter Activity Cytidine Transmembrane Transporter Activity Uridine Transmembrane Transporter Activity
	Biological Process	Mitochondrial Proton-transporting ATP Synthase Complex Assembly	Neurotransmitter Uptake Neurotransmitter Transport Xenobiotic Transmembrane Transport Nucleobase Transport Adenine Transport Guanine Transport Nucleoside Transport Purine Nucleoside Transmembrane Transport Cytidine Transport Uridine Transmembrane Transport Adenosine Transport Inosine Transport Hypoxanthine Transport Thymine Transport Pyrimidine-containing Compound Transmembrane Transport Transport Across Blood-brain Barrier Nucleoside Transmembrane Transport Guanine Transmembrane Transport Uracil Transmembrane Transport Purine Nucleobase Transmembrane Transport
Pathways			Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane Azathioprine ADME
Drugs			Ethanol
Diseases
GWAS		Ankle-brachial index ( 31388106) General risk tolerance (MTAG) ( 30643258) Lipoprotein (a) levels ( 26377243)	Bipolar disorder ( 21926972) Serum metabolite levels ( 33031748) Serum uric acid levels ( 32514006)
Interacting Genes		36 interacting genes: AQP6 ATP6V0B BCL2L13 CNR2 CYB561 EBP ELOVL4 GGT7 GHITM GJA8 GOLT1A GPR42 GRINA HSD17B11 IL10RA JAGN1 MFSD2A MFSD6 MSMO1 MTIF3 NDUFA3 PLP1 RNF5 SGPL1 SLC10A1 SLC10A6 SLC19A3 SLC29A2 SLC30A3 SYNJ2BP TMBIM1 TMEM179B TMEM31 TMEM51 TMIE VKORC1	19 interacting genes: ALOX5AP CERS3 CERS4 CREB3 ERGIC3 GJA4 GPR152 LAPTM4B PLPP5 SERINC2 SLC10A1 SLC10A6 TMEM237 TMEM242 TMEM33 TMEM86B TMX2 UBQLN1 UBQLN2
Entrez ID		729515	3177
HPRD ID			03662
Ensembl ID		ENSG00000215712	ENSG00000174669
Uniprot IDs		Q9NWH2	Q14542 Q96FB2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Endoplasmic Reticulum Bile Acid:sodium Symporter Activity Monoatomic Ion Transport Lipid Biosynthetic Process Monoatomic Cation Transport Inorganic Cation Transmembrane Transport Endoplasmic Reticulum Membrane Small Molecule Biosynthetic Process Pyrimidine-containing Compound Transmembrane Transport Inorganic Ion Transmembrane Transport Monoatomic Ion Transmembrane Transport Calcium Channel Activity Steroid Biosynthetic Process Bile Acid And Bile Salt Transport	Membrane Regulation Of Response To Endoplasmic Reticulum Stress Endoplasmic Reticulum Membrane Endoplasmic Reticulum Bile Acid:sodium Symporter Activity Positive Regulation Of Response To Endoplasmic Reticulum Stress Sphingosine N-acyltransferase Activity Response To Endoplasmic Reticulum Stress Positive Regulation Of ERAD Pathway Bile Acid And Bile Salt Transport Regulation Of ERAD Pathway Positive Regulation Of Deacetylase Activity Polyubiquitin Modification-dependent Protein Binding Negative Regulation Of Store-operated Calcium Channel Activity D-lysine 5,6-aminomutase Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Leukotriene Production Involved In Inflammatory Response Regulation Of Vacuole Organization Negative Regulation Of G Protein-coupled Receptor Internalization Retrograde Transporter Complex, Golgi To ER Regulation Of Lysosomal Membrane Permeability Ceramide Biosynthetic Process Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity
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