TMEM242 and MFSD2A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM242	MFSD2A
Description		transmembrane protein 242	MFSD2 lysolipid transporter A, lysophospholipid
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Protein Binding	Long-chain Fatty Acid Transmembrane Transporter Activity Protein Binding Phospholipid Transporter Activity Fatty Acid Transmembrane Transporter Activity Symporter Activity Lysophospholipid:sodium Symporter Activity Lysophosphatidylcholine Flippase Activity Oleate Transmembrane Transporter Activity
	Biological Process	Mitochondrial Proton-transporting ATP Synthase Complex Assembly	Retinal Pigment Epithelium Development Phosphatidylcholine Biosynthetic Process Lipid Transport Brain Development Photoreceptor Cell Morphogenesis Carbohydrate Transport Cellular Response To Starvation Positive Regulation Of Triglyceride Biosynthetic Process Fatty Acid Transport Long-chain Fatty Acid Transport Hippocampus Development Positive Regulation Of Cell Growth Negative Regulation Of Fatty Acid Beta-oxidation Lipid Translocation Very-low-density Lipoprotein Particle Assembly Maintenance Of Blood-brain Barrier Photoreceptor Cell Outer Segment Organization Regulation Of Multicellular Organism Growth Transcytosis Regulation Of Dendrite Development Cognition Lysophospholipid Transport Transmembrane Transport Retina Morphogenesis In Camera-type Eye Establishment Of Blood-brain Barrier Motor Behavior Energy Homeostasis Lysophospholipid Translocation Regulation Of Neuron Projection Arborization Transport Across Blood-brain Barrier Regulation Of Phosphatidylcholine Metabolic Process Regulation Of Phosphatidylethanolamine Metabolic Process Regulation Of Phosphatidylserine Metabolic Process Lipid Transport Across Blood-brain Barrier Embryonic Brain Development Establishment Of Blood-retinal Barrier
Pathways			Synthesis of PC
Drugs
Diseases
GWAS		Ankle-brachial index ( 31388106) General risk tolerance (MTAG) ( 30643258) Lipoprotein (a) levels ( 26377243)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Mean platelet volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 28957414) Refractive error ( 32231278) Time to smoke first cigarette in the morning ( 31294817) Triglyceride levels ( 32203549)
Interacting Genes		36 interacting genes: AQP6 ATP6V0B BCL2L13 CNR2 CYB561 EBP ELOVL4 GGT7 GHITM GJA8 GOLT1A GPR42 GRINA HSD17B11 IL10RA JAGN1 MFSD2A MFSD6 MSMO1 MTIF3 NDUFA3 PLP1 RNF5 SGPL1 SLC10A1 SLC10A6 SLC19A3 SLC29A2 SLC30A3 SYNJ2BP TMBIM1 TMEM179B TMEM31 TMEM51 TMIE VKORC1	2 interacting genes: ADRB2 TMEM242
Entrez ID		729515	84879
HPRD ID			07861
Ensembl ID		ENSG00000215712	ENSG00000168389
Uniprot IDs		Q9NWH2	B4DNN7 E7EPI8 Q71RE4 Q8NA29
PDB IDs			7OIX
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Endoplasmic Reticulum Bile Acid:sodium Symporter Activity Monoatomic Ion Transport Lipid Biosynthetic Process Monoatomic Cation Transport Inorganic Cation Transmembrane Transport Endoplasmic Reticulum Membrane Small Molecule Biosynthetic Process Pyrimidine-containing Compound Transmembrane Transport Inorganic Ion Transmembrane Transport Monoatomic Ion Transmembrane Transport Calcium Channel Activity Steroid Biosynthetic Process Bile Acid And Bile Salt Transport	Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Response To Psychosocial Stress Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Norepinephrine Binding Positive Regulation Of Lipophagy AMPA Selective Glutamate Receptor Signaling Pathway Beta2-adrenergic Receptor Activity Positive Regulation Of Autophagosome Maturation Heat Generation Mitochondrial Proton-transporting ATP Synthase Complex Assembly Proton-transporting ATP Synthase Complex Assembly Adrenergic Receptor Activity Diet Induced Thermogenesis Adenylate Cyclase Binding Negative Regulation Of Smooth Muscle Contraction Negative Regulation Of Multicellular Organism Growth Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Autophagosome Maturation Positive Regulation Of CAMP/PKA Signal Transduction Negative Regulation Of Muscle Contraction Neuronal Dense Core Vesicle Adrenergic Receptor Signaling Pathway Negative Regulation Of Systemic Arterial Blood Pressure Adaptive Thermogenesis Bone Resorption Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Brown Fat Cell Differentiation Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Excitatory Postsynaptic Potential Temperature Homeostasis Positive Regulation Of Protein-containing Complex Disassembly Regulation Of CAMP/PKA Signal Transduction Potassium Channel Regulator Activity Ligand-gated Ion Channel Signaling Pathway Regulation Of Systemic Arterial Blood Pressure Response To Cold Positive Regulation Of Bone Mineralization Glutamate Receptor Signaling Pathway Cellular Response To Amyloid-beta Modulation Of Excitatory Postsynaptic Potential Negative Regulation Of Blood Pressure Positive Regulation Of Biomineral Tissue Development Smooth Muscle Contraction Vasodilation Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Ossification Endosome To Lysosome Transport Regulation Of Smooth Muscle Contraction
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?