TMEM242 and MSMO1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM242	MSMO1
Description		transmembrane protein 242	methylsterol monooxygenase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane
	Molecular Function	Protein Binding	C-4 Methylsterol Oxidase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity
	Biological Process	Mitochondrial Proton-transporting ATP Synthase Complex Assembly	Lipid Metabolic Process Fatty Acid Metabolic Process Steroid Biosynthetic Process Cholesterol Biosynthetic Process Steroid Metabolic Process Cholesterol Metabolic Process Lipid Biosynthetic Process Sterol Biosynthetic Process
Pathways			Cholesterol biosynthesis Cholesterol biosynthesis via lathosterol
Drugs			NADH
Diseases
GWAS		Ankle-brachial index ( 31388106) General risk tolerance (MTAG) ( 30643258) Lipoprotein (a) levels ( 26377243)	Heel bone mineral density ( 30598549) Neuroticism ( 27067015)
Interacting Genes		36 interacting genes: AQP6 ATP6V0B BCL2L13 CNR2 CYB561 EBP ELOVL4 GGT7 GHITM GJA8 GOLT1A GPR42 GRINA HSD17B11 IL10RA JAGN1 MFSD2A MFSD6 MSMO1 MTIF3 NDUFA3 PLP1 RNF5 SGPL1 SLC10A1 SLC10A6 SLC19A3 SLC29A2 SLC30A3 SYNJ2BP TMBIM1 TMEM179B TMEM31 TMEM51 TMIE VKORC1	19 interacting genes: ATXN1 CHRM5 CYP4F22 DNAJC30 ERG28 GOLT1A GPR35 HMOX1 MARCHF6 MMP14 STRIT1 STX3 TMEM11 TMEM140 TMEM242 TMEM65 TMEM86B VKORC1 YIF1A
Entrez ID		729515	6307
HPRD ID			07396
Ensembl ID		ENSG00000215712	ENSG00000052802
Uniprot IDs		Q9NWH2	Q15800
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Endoplasmic Reticulum Bile Acid:sodium Symporter Activity Monoatomic Ion Transport Lipid Biosynthetic Process Monoatomic Cation Transport Inorganic Cation Transmembrane Transport Endoplasmic Reticulum Membrane Small Molecule Biosynthetic Process Pyrimidine-containing Compound Transmembrane Transport Inorganic Ion Transmembrane Transport Monoatomic Ion Transmembrane Transport Calcium Channel Activity Steroid Biosynthetic Process Bile Acid And Bile Salt Transport	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane
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