IL10RA

Gene Name		interleukin 10 receptor, alpha
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Signal Transducer Activity Receptor Activity Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding
	Biological Process	Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-protein Interactions		3 interactors: IL10 IL10RB JAK1
Entrez ID		3587
HPRD ID		00911
Ensembl ID		ENSG00000110324
Uniprot IDs		Q13651
PDB IDs		1J7V 1LQS 1Y6K 1Y6M 1Y6N
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Interferon-alpha Biosynthetic Process Negative Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Immune Response Defense Response Interleukin-2-mediated Signaling Pathway Response To Carbon Monoxide Negative Regulation Of Myeloid Dendritic Cell Activation Cellular Response To Organic Substance Negative Regulation Of Tumor Necrosis Factor Biosynthetic Process Positive Regulation Of B Cell Apoptotic Process Negative Regulation Of Membrane Protein Ectodomain Proteolysis Negative Regulation Of MHC Class II Biosynthetic Process Regulation Of Myeloid Dendritic Cell Activation Immune System Process Receptor Biosynthetic Process Cytoplasmic Sequestering Of NF-kappaB Negative Regulation Of Chronic Inflammatory Response Negative Regulation Of Cytokine Secretion Involved In Immune Response Positive Regulation Of MHC Class II Biosynthetic Process Inflammatory Response Cytokine-mediated Signaling Pathway Type 2 Immune Response Response To Organic Substance Response To Interleukin-2 Branching Involved In Labyrinthine Layer Morphogenesis Response To Inactivity Negative Regulation Of Inflammatory Response To Antigenic Stimulus Regulation Of Cytokine Secretion Involved In Immune Response Regulation Of Chronic Inflammatory Response Cellular Response To Cytokine Stimulus Negative Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of B Cell Proliferation Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Negative Regulation Of NF-kappaB Import Into Nucleus Regulation Of B Cell Apoptotic Process Regulation Of Tumor Necrosis Factor Biosynthetic Process Cellular Response To Estradiol Stimulus Positive Regulation Of Lymphocyte Apoptotic Process Response To Cytokine Response To Other Organism Negative Regulation Of Interleukin-12 Production Cytoplasmic Sequestering Of Transcription Factor Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Labyrinthine Layer Morphogenesis Response To Biotic Stimulus Cytoplasmic Sequestering Of Protein Response To Stress Regulation Of Sensory Perception Of Pain Negative Regulation Of Growth Of Symbiont In Host
Tagcloud ?		bioinformatics bmp2 calm1 cnaq csf2rb csf3 expressions fifteen gria2 il3ra il6st lifr lymphatic microarrays myl9 mylk myosin nonsmokers nsclc paraneoplastic pathohistological plcb4 ppp2ca rac3 rock2 thbs1 verify