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IL10RA

Name interleukin 10 receptor subunit alpha
Structure PDB 1J7V
Novel Interactors 2 novel interactors: DRD2 KMT2A
Interactors 20 interactors: BTRC C1QL4 CDS2 CMTM3 HACD1 IL10 IL10RB JAK1 MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6
GO Annotations Cellular Component
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
  • Plasma Membrane
  • Cilium
  • Membrane
  • Apical Plasma Membrane
Molecular Function
  • Interleukin-10 Receptor Activity
  • Protein Binding
  • Interleukin-10 Binding
  • Signaling Receptor Activity
Biological Process
  • Negative Regulation Of Autophagy
  • Cytokine-mediated Signaling Pathway
  • Response To Lipopolysaccharide
  • Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT
  • Negative Regulation Of Inflammatory Response
  • Regulation Of Synapse Organization
  • Intestinal Epithelial Structure Maintenance
  • Ubiquitin-dependent Endocytosis
  • Interleukin-10-mediated Signaling Pathway
Pathways
  • Interleukin-10 signaling
  • Nuclear events stimulated by ALK signaling in cancer
GWAS
  • Obesity-related traits ( 23251661 )
Entrez ID 3587
HPRD ID 00911
Ensembl ID ENSG00000110324
Uniprot IDs Q13651
PDB IDs 1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI 6X93
GO Terms Enriched among Interactors ?
  • Interleukin-10-mediated Signaling Pathway
  • Membrane
  • Response To Inactivity
  • Type III Interferon-mediated Signaling Pathway

© Madhavi K. Ganapathiraju 2012-2026