IL10RA and C1QL4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IL10RA	C1QL4
Description		interleukin 10 receptor subunit alpha	complement C1q like 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cilium Membrane Apical Plasma Membrane	Extracellular Region Collagen Trimer Extracellular Space
	Molecular Function	Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding Signaling Receptor Activity	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Autophagy Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Inflammatory Response Regulation Of Synapse Organization Intestinal Epithelial Structure Maintenance Ubiquitin-dependent Endocytosis Interleukin-10-mediated Signaling Pathway	Negative Regulation Of Fat Cell Differentiation Fibroblast Proliferation Negative Regulation Of Fibroblast Proliferation ERK1 And ERK2 Cascade Negative Regulation Of ERK1 And ERK2 Cascade
Pathways		Interleukin-10 signaling Nuclear events stimulated by ALK signaling in cancer
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		20 interacting genes: BTRC C1QL4 CDS2 CMTM3 HACD1 IL10 IL10RB JAK1 MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6	19 interacting genes: CD53 CERS4 FATE1 FNDC9 GOLM1 GPR152 IL10RA LEUTX MFF RHCG SCARA5 SGTA SGTB SLC38A1 SSMEM1 TMEM179B TMPRSS2 TRHR UBQLN2
Entrez ID		3587	338761
HPRD ID		00911	17350
Ensembl ID		ENSG00000110324	ENSG00000186897
Uniprot IDs		Q13651	A0A3B0INP7 Q86Z23
PDB IDs		1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI 6X93
Enriched GO Terms of Interacting Partners?		Interleukin-10-mediated Signaling Pathway Membrane Response To Inactivity Type III Interferon-mediated Signaling Pathway	Membrane TRC Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Positive Regulation Of ERAD Pathway Identical Protein Binding Regulation Of ERAD Pathway Establishment Of Protein Localization To Organelle Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Interleukin-10 Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Thyrotropin-releasing Hormone Receptor Activity Ferritin Receptor Activity Protein Targeting
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