IL10RA and CDS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IL10RA	CDS2
Description		interleukin 10 receptor subunit alpha	CDP-diacylglycerol synthase 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cilium Membrane Apical Plasma Membrane	Mitochondrial Inner Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding Signaling Receptor Activity	Phosphatidate Cytidylyltransferase Activity Protein Binding Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups Nucleotidyltransferase Activity
	Biological Process	Negative Regulation Of Autophagy Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Inflammatory Response Regulation Of Synapse Organization Intestinal Epithelial Structure Maintenance Ubiquitin-dependent Endocytosis Interleukin-10-mediated Signaling Pathway	Lipid Metabolic Process Phosphatidylglycerol Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process Lipid Droplet Formation
Pathways		Interleukin-10 signaling Nuclear events stimulated by ALK signaling in cancer	Synthesis of PG
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		20 interacting genes: BTRC C1QL4 CDS2 CMTM3 HACD1 IL10 IL10RB JAK1 MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6	28 interacting genes: BIK CPLX4 CREB3 ERGIC3 FAM209A FKBP7 GPR152 GPX8 HIBADH IL10RA JSRP1 LEUTX LHFPL5 LMNA MR1 MTIF3 MYG1 RNF122 SAR1A SSMEM1 TIMMDC1 TMEM139 TMEM45B TMX2 TRIM55 TRIM63 TSG101 TSPAN12
Entrez ID		3587	8760
HPRD ID		00911	09150
Ensembl ID		ENSG00000110324	ENSG00000101290
Uniprot IDs		Q13651	O95674
PDB IDs		1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI 6X93
Enriched GO Terms of Interacting Partners?		Interleukin-10-mediated Signaling Pathway Membrane Response To Inactivity Type III Interferon-mediated Signaling Pathway
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