IL9R and IL2RG

Number of citations of the paper that reports this interaction (PMID 11418623)
76

Data Source:
HPRD (in vivo)

		IL9R	IL2RG
Gene Name		interleukin 9 receptor	interleukin 2 receptor, gamma
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Interleukin-9 Receptor Activity Interleukin-9 Binding	Interleukin-2 Receptor Activity Interleukin-4 Receptor Activity Interleukin-7 Receptor Activity Protein Binding Interleukin-2 Binding Interleukin-7 Binding
	Biological Process	Signal Transduction Cell Proliferation Positive Regulation Of Cell Growth Interleukin-9-mediated Signaling Pathway	Immune Response Signal Transduction Viral Process Interleukin-4-mediated Signaling Pathway Interleukin-2-mediated Signaling Pathway Interleukin-7-mediated Signaling Pathway
Pathways			Signaling by GPCR G-protein beta:gamma signalling Cytokine Signaling in Immune system Signaling by Interleukins GPCR downstream signaling Interleukin receptor SHC signaling G beta:gamma signalling through PI3Kgamma Interleukin receptor SHC signaling Interleukin-7 signaling GPVI-mediated activation cascade Interleukin-2 signaling Platelet activation, signaling and aggregation Interleukin-3, 5 and GM-CSF signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CRADD IL2RG IL9 JAK1 KAT5 YWHAZ	24 interactors: AXL CAPNS1 ICAM1 IL15 IL15RA IL2 IL2RB IL4 IL4R IL7 IL7R IL9R JAK1 JAK3 KRTAP10-3 NOTCH2NL PTPRJ SHB SHC1 STAT1 STAT5A STK4 WWP1 WWP2
Entrez ID		3581	3561
HPRD ID		02052	02391
Ensembl ID		ENSG00000124334	ENSG00000147168
Uniprot IDs		Q01113	P31785 Q5FC09
PDB IDs			1ILL 1ILM 1ILN 1ITE 2B5I 2ERJ 3BPL 3QAZ 3QB7 4GS7
Enriched GO Terms of Interacting Partners?		Interleukin-2-mediated Signaling Pathway Response To Interleukin-2 Immune Response DNA Damage Response, Signal Transduction By P53 Class Mediator Signal Transduction In Response To DNA Damage Positive Regulation Of Interleukin-5 Biosynthetic Process Signal Transduction By P53 Class Mediator Response To Stress Interleukin-7-mediated Signaling Pathway Intracellular Signal Transduction Immune System Process Golgi Reassembly Positive Regulation Of Apoptotic Signaling Pathway Histamine Secretion By Mast Cell Establishment Of Golgi Localization Response To Stimulus Golgi Inheritance Histamine Secretion Positive Regulation Of Protein Metabolic Process Signal Transduction Histamine Transport Interleukin-4-mediated Signaling Pathway Apoptotic Signaling Pathway Defense Response DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Signaling Golgi Localization Cell Communication Positive Regulation Of Interleukin-5 Production Inflammatory Response Cellular Response To Estradiol Stimulus Mast Cell Degranulation Cytokine-mediated Signaling Pathway Negative Regulation Of Interleukin-2 Production Production Of Molecular Mediator Involved In Inflammatory Response Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Mast Cell Mediated Immunity Positive Regulation Of Protein Acetylation Regulation Of Interleukin-5 Production Lysosome Localization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cytokine Production Mast Cell Activation Cellular Response To Estrogen Stimulus Viral Process Cellular Response To Stimulus Cellular Response To Organic Substance	Regulation Of Lymphocyte Differentiation Positive Regulation Of Lymphocyte Differentiation Positive Regulation Of Cell Activation Regulation Of T Cell Differentiation Response To Cytokine Regulation Of Immune System Process Cellular Response To Cytokine Stimulus Cytokine-mediated Signaling Pathway Regulation Of Cell Activation Positive Regulation Of T Cell Activation Signaling Positive Regulation Of Homotypic Cell-cell Adhesion Cell Communication Positive Regulation Of Cell Adhesion Lymphocyte Differentiation Positive Regulation Of Cell-cell Adhesion Regulation Of Lymphocyte Activation Cell Surface Receptor Signaling Pathway Signal Transduction Lymphocyte Activation Regulation Of Cell Adhesion Regulation Of Cell Proliferation Regulation Of Immune Response Positive Regulation Of T Cell Differentiation Positive Regulation Of Immune System Process Regulation Of T Cell Activation Cell Activation Leukocyte Activation Immune Response Leukocyte Differentiation Immune System Process Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Regulation Of Cell-cell Adhesion Negative Regulation Of Immune System Process Cellular Response To Organic Substance Hemopoiesis Cellular Response To Stimulus T Cell Differentiation T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Response To Organic Substance Immune System Development Leukocyte Cell-cell Adhesion Positive Regulation Of T Cell Proliferation Homotypic Cell-cell Adhesion Single Organismal Cell-cell Adhesion Response To Stimulus
Tagcloud ?		augment bifunctional biopharmaceutical borne clustering designer desirable door engineered fusokine fusokines gift9 gmcsf gmcsfr granulocyte hereafter heretofore heterologous jak1 jak3 notion opens pharmaceutical therapeutically transhyperphosphorylation translates transphosphorylation unrealized	1ada 1p24 antiretroviral atazanavir atv boosted capacities carriage coating depots fa folic loads mirrored nanoart nanocrystals nanoformulated p407 parafollicular paralleled permit pharmacodynamic poloxamer prkdc reconstituted ritonavir szj tm1wjl untargeted
Tagcloud (Difference) ?		augment bifunctional biopharmaceutical borne clustering designer desirable door engineered fusokine fusokines gift9 gmcsf gmcsfr granulocyte hereafter heretofore heterologous jak1 jak3 notion opens pharmaceutical therapeutically transhyperphosphorylation translates transphosphorylation unrealized	1ada 1p24 antiretroviral atazanavir atv boosted capacities carriage coating depots fa folic loads mirrored nanoart nanocrystals nanoformulated p407 parafollicular paralleled permit pharmacodynamic poloxamer prkdc reconstituted ritonavir szj tm1wjl untargeted
Tagcloud (Intersection) ?