CXCL3 and XCL2

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		CXCL3	XCL2
Description		C-X-C motif chemokine ligand 3	X-C motif chemokine ligand 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Chemokine Activity	Cytokine Activity Protein Binding Chemokine Activity CCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Neutrophil Chemotaxis Killing Of Cells Of Another Organism Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide	Chemotaxis Inflammatory Response Immune Response Signal Transduction Blood Circulation Positive Regulation Of Cell Migration Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (q) signalling events
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Urate levels (BMI interaction) ( 25811787)	Emphysema imaging phenotypes ( 26030696) Lung cancer ( 28604730) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		6 interacting genes: CCL11 CXCL5 CXCL6 CXCR1 CXCR2 XCL2	19 interacting genes: CCL2 CCL20 CCL21 CCL26 CCL28 CCL5 CCL7 CCL8 CXCL12 CXCL17 CXCL2 CXCL3 CXCL5 KRTAP1-3 KRTAP10-9 NOTCH2NLA PF4 PF4V1 XCR1
Entrez ID		2921	6846
HPRD ID		00742	05317
Ensembl ID		ENSG00000163734	ENSG00000143185
Uniprot IDs		P19876	Q9UBD3
PDB IDs		8XWF 8XX3
Enriched GO Terms of Interacting Partners?		Cell Chemotaxis Granulocyte Chemotaxis Chemokine-mediated Signaling Pathway Granulocyte Migration Chemotaxis Locomotion Myeloid Leukocyte Migration Leukocyte Chemotaxis Chemokine Activity Neutrophil Chemotaxis Leukocyte Migration Neutrophil Migration Cell Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cytokine-mediated Signaling Pathway Cell Motility Interleukin-8-mediated Signaling Pathway Immune Response Interleukin-8 Receptor Activity Antimicrobial Humoral Response Inflammatory Response Interleukin-8 Binding Cytokine Activity Humoral Immune Response G Protein-coupled Receptor Signaling Pathway Immune System Process C-X-C Chemokine Receptor Activity CXCR Chemokine Receptor Binding Dendritic Cell Chemotaxis Defense Response Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Dendritic Cell Migration CCR Chemokine Receptor Binding Neutrophil Activation Defense Response To Symbiont Defense Response To Other Organism Cell Surface Receptor Signaling Pathway Signal Transduction Response To Other Organism Receptor Internalization Response To External Biotic Stimulus Secretory Granule Membrane Mononuclear Cell Migration Extracellular Space Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Myeloid Leukocyte Activation Response To Stress Mammary Duct Terminal End Bud Growth	Chemokine Activity Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemotaxis Antimicrobial Humoral Response Locomotion Leukocyte Chemotaxis Cytokine Activity Leukocyte Migration Humoral Immune Response Granulocyte Chemotaxis Myeloid Leukocyte Migration Granulocyte Migration Cell Migration Inflammatory Response Cell Motility Defense Response To Symbiont Defense Response To Other Organism Mononuclear Cell Migration Immune Response Chemokine-mediated Signaling Pathway Eosinophil Chemotaxis Eosinophil Migration Defense Response Response To Other Organism CCR Chemokine Receptor Binding Immune System Process Extracellular Space Killing Of Cells Of Another Organism Regulation Of Leukocyte Migration CXCR Chemokine Receptor Binding Extracellular Region Response To External Biotic Stimulus Positive Regulation Of Leukocyte Migration Positive Regulation Of Mononuclear Cell Migration Cell Killing Monocyte Chemotaxis Regulation Of Lymphocyte Migration Positive Regulation Of Chemotaxis Regulation Of Mononuclear Cell Migration Cytokine-mediated Signaling Pathway Chemokine Receptor Binding Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Lymphocyte Migration Regulation Of Chemotaxis Positive Regulation Of Cell Migration Neutrophil Chemotaxis Positive Regulation Of Cell Motility Negative Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Locomotion
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