CXCL3

Gene Name		chemokine (C-X-C motif) ligand 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Chemokine Activity CXCR Chemokine Receptor Binding
	Biological Process	Positive Regulation Of Leukocyte Chemotaxis Inflammatory Response Immune Response G-protein Coupled Receptor Signaling Pathway Neutrophil Chemotaxis Response To Lipopolysaccharide Regulation Of Cell Proliferation Chemokine-mediated Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-protein Interactions		2 interactors: CXCR1 CXCR2
Entrez ID		2921
HPRD ID		00742
Ensembl ID		ENSG00000163734
Uniprot IDs		P19876
PDB IDs
Enriched GO Terms of Interacting Partners?		Interleukin-8-mediated Signaling Pathway Dendritic Cell Chemotaxis Dendritic Cell Migration Receptor Internalization Chemokine-mediated Signaling Pathway Receptor Metabolic Process Leukocyte Chemotaxis Cell Chemotaxis Negative Regulation Of Neutrophil Apoptotic Process Leukocyte Migration Receptor-mediated Endocytosis Inflammatory Response Cytokine-mediated Signaling Pathway Acute Inflammatory Response To Antigenic Stimulus Cellular Response To Cytokine Stimulus Chemotaxis Positive Regulation Of Vascular Permeability Endocytosis Metanephric Tubule Morphogenesis Response To Cytokine Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Cell Migration Negative Regulation Of Myeloid Cell Apoptotic Process Cell Motility Positive Regulation Of Neutrophil Chemotaxis Neutrophil Activation Positive Regulation Of Granulocyte Chemotaxis Regulation Of Neutrophil Chemotaxis Metanephric Epithelium Development Regulation Of Neutrophil Migration Regulation Of Vascular Permeability G-protein Coupled Receptor Signaling Pathway Inflammatory Response To Antigenic Stimulus Regulation Of Granulocyte Chemotaxis Locomotion Regulation Of Myeloid Cell Apoptotic Process Defense Response Vesicle-mediated Transport Neutrophil Chemotaxis Movement Of Cell Or Subcellular Component Neutrophil Migration Negative Regulation Of Leukocyte Apoptotic Process Regulation Of Muscle Cell Apoptotic Process Cellular Defense Response Granulocyte Chemotaxis Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Leukocyte Chemotaxis Response To External Stimulus Acute Inflammatory Response Cellular Response To Organic Substance
Tagcloud ?		1beta a549 alveolar array cc ccl2 ccl5 chemokine chemokines clearly cxcl1 cxcl11 cxcl2 cxcl5 cxcl6 cxcl8 cytokines elisa epithelial immunoluminometric multiplex overlapping repetitive share signalling similarities stimulate supernatants