CXCL3

Description		C-X-C motif chemokine ligand 3
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Chemokine Activity
	Biological Process	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Neutrophil Chemotaxis Killing Of Cells Of Another Organism Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		6 interacting genes: CCL11 CXCL5 CXCL6 CXCR1 CXCR2 XCL2
Entrez ID		2921
HPRD ID		00742
Ensembl ID		ENSG00000163734
Uniprot IDs		P19876
PDB IDs		8XWF 8XX3
Enriched GO Terms of Interacting Partners?		Cell Chemotaxis Granulocyte Chemotaxis Chemokine-mediated Signaling Pathway Granulocyte Migration Chemotaxis Locomotion Myeloid Leukocyte Migration Leukocyte Chemotaxis Chemokine Activity Neutrophil Chemotaxis Leukocyte Migration Neutrophil Migration Cell Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cytokine-mediated Signaling Pathway Cell Motility Interleukin-8-mediated Signaling Pathway Immune Response Interleukin-8 Receptor Activity Antimicrobial Humoral Response Inflammatory Response Interleukin-8 Binding Cytokine Activity Humoral Immune Response G Protein-coupled Receptor Signaling Pathway Immune System Process C-X-C Chemokine Receptor Activity CXCR Chemokine Receptor Binding Dendritic Cell Chemotaxis Defense Response Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Dendritic Cell Migration CCR Chemokine Receptor Binding Neutrophil Activation Defense Response To Symbiont Defense Response To Other Organism Cell Surface Receptor Signaling Pathway Signal Transduction Response To Other Organism Receptor Internalization Response To External Biotic Stimulus Secretory Granule Membrane Mononuclear Cell Migration Extracellular Space Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Myeloid Leukocyte Activation Response To Stress Mammary Duct Terminal End Bud Growth
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