IK and SUPT5H

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		IK	SUPT5H
Description		IK cytokine	SPT5 homolog, DSIF elongation factor subunit
Image
GO Annotations	Cellular Component	Nuclear Chromosome Spindle Pole Nucleus Nucleoplasm Spliceosomal Complex Chromosome Cytoplasm Cytoskeleton Nuclear Speck U2-type Precatalytic Spliceosome Mitotic Spindle Pole	Nucleus Nucleoplasm DSIF Complex
	Molecular Function	Protein Binding Identical Protein Binding	Chromatin Binding RNA Binding MRNA Binding Protein Binding Enzyme Binding Protein Heterodimerization Activity
	Biological Process	Mitotic Cell Cycle MRNA Splicing, Via Spliceosome MRNA Processing Mitotic Spindle Assembly Checkpoint Signaling RNA Splicing Protein Localization To Kinetochore	Negative Regulation Of Transcription By RNA Polymerase II DNA-templated Transcription Elongation Regulation Of Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II Positive Regulation Of Macroautophagy Regulation Of DNA-templated Transcription Elongation Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		mRNA Splicing - Major Pathway	Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA polymerase II transcribes snRNA genes mRNA Capping RNA Polymerase II Transcription Elongation RNA Pol II CTD phosphorylation and interaction with CE
Drugs
Diseases
GWAS		Monocyte count ( 32888494) Schizophrenia ( 29483656) Serum immune biomarker levels ( 32066700)	Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		28 interacting genes: APP CEBPA CEP70 CHD3 CTNNBL1 DDX6 EGLN3 FANCC FRA10AC1 FXR1 GRB2 KAT5 KDM1A MBD3 MFAP1 NUP62 OGT PFN2 QARS1 RACK1 RBM10 SUPT5H THOC1 TOE1 TRIM55 TRIM63 TTC14 ZCCHC10	51 interacting genes: C9orf78 CCNH CCNT2 CDK7 CDK9 CEP55 CPSF7 CSNK2A1 DBN1 DCAF6 DSCAM EXOSC7 FHL3 GOLGA2 GTF3C1 H2AX HSPB1 HTATSF1 IK IKBKG LMAN2 MAD1L1 MAML3 MNAT1 PCBD1 PGK1 PHYHIP PIN1 PNO1 POLR2A PPIA PPP2R2D PRMT1 PRMT5 RPL9 SAP30BP SIK1 SNRNP48 SNX4 SSBP3 SUMO2 SUPT4H1 TERF1 TEX11 TLE5 XRCC5 YBX2 ZBTB3 ZFYVE9 ZNF496 ZNF512B
Entrez ID		3550	6829
HPRD ID		02771	03655
Ensembl ID		ENSG00000113141	ENSG00000196235
Uniprot IDs		Q13123 Q95HA6 Q9UK43	O00267
PDB IDs		5O9Z 6Q8I 8QO9 8QZS	2DO3 2E6Z 2E70 3H7H 4L1U 5OHO 5OHQ 5OIK 5U98 6EQY 6ER0 6GMH 6GML 6TED 7OKX 7OKY 7OL0 7PKS 7UNC 7UND 7YCX 8A3Y 8P4C 8P4D 8P4E 8P4F 8RBX 8UHA 8UHD 8UHG 8UI0 8UIS 8W8E 8W8F 9EGX 9EGY 9EGZ 9EH0 9EH2 9J0N 9J0O 9J0P
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus PTB Domain Binding Negative Regulation Of RNA Metabolic Process Chromatin Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process Nucleoplasm Negative Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Apoptotic Process Regulation Of Glycolytic Process Programmed Cell Death Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Cell Death Regulation Of Programmed Cell Death RNA Binding Membraneless Organelle Assembly Cellular Response To Glucose Stimulus Regulation Of Carbohydrate Catabolic Process Negative Regulation Of Long-term Synaptic Potentiation Protein-containing Complex Nucleic Acid Metabolic Process Positive Regulation Of Proteolysis Regulation Of ATP Metabolic Process Positive Regulation Of Catabolic Process Negative Regulation Of Gene Expression Regulation Of Purine Nucleotide Metabolic Process Regulation Of Apoptotic Process Carbohydrate Homeostasis Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Glucose Homeostasis Regulation Of Stem Cell Differentiation NuRD Complex Negative Regulation Of Translation Nucleic Acid Binding MRNA Splicing, Via Spliceosome RNA Splicing Cellular Response To Carbohydrate Stimulus Positive Regulation Of RNA Metabolic Process Post-transcriptional Regulation Of Gene Expression RNA Splicing, Via Transesterification Reactions Positive Regulation Of Metabolic Process Translation Regulator Activity Intracellular Glucose Homeostasis	Nucleus Nucleic Acid Metabolic Process Transcription Factor TFIIK Complex CAK-ERCC2 Complex Regulation Of Nucleobase-containing Compound Metabolic Process Nucleoplasm Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Cycle Process Regulation Of Primary Metabolic Process Regulation Of Cell Cycle Regulation Of RNA Metabolic Process DNA-templated Transcription Initiation Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Macromolecule Metabolic Process Transcription Factor TFIIH Core Complex Transcription Factor TFIIH Holo Complex Nucleobase-containing Compound Biosynthetic Process Regulation Of Gene Expression Transcription Elongation By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Regulation Of Mitotic Cell Cycle Protein Localization To Chromosome Regulation Of Macromolecule Metabolic Process DNA-templated Transcription Elongation Protein Peptidyl-prolyl Isomerization Chromosome Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Chromosome Segregation DNA Metabolic Process Recombinational Repair Protein Localization To Site Of Double-strand Break Protein Binding DNA Recombination Transcription Pausing By RNA Polymerase II Postsynaptic Cytosol Histone H4R3 Methyltransferase Activity Peptidyl-arginine Methylation DNA Repair Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Anoikis Regulation Of Transcription Elongation By RNA Polymerase II Transcription Elongation-coupled Chromatin Remodeling Macromolecule Biosynthetic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?