IK and FANCC

Number of citations of the paper that reports this interaction (PMID 14499622)
5

Data Source:
BioGRID (two hybrid)

		IK	FANCC
Gene Name		IK cytokine, down-regulator of HLA II	Fanconi anemia, complementation group C
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleoplasm Nucleolus	Nucleus Nucleoplasm Cytoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Immune Response Cell-cell Signaling	Myeloid Cell Homeostasis DNA Repair Nucleotide-excision Repair Protein Complex Assembly Germ Cell Development Removal Of Superoxide Radicals
Pathways			Fanconi Anemia pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: APP CEP70 CHD3 CTNNBL1 FANCC FRA10AC1 GNB2L1 GRB2 KAT5 KDM1A MFAP1 NUP62 PFN2 RBM10 SUPT5H THOC1 TOE1 TTC14 ZCCHC10	27 interactors: ATP6 AZIN1 CAPN10 CDK1 DNAJB1 FANCA FANCD2 FANCE FANCF FANCG GSTP1 HSP90AA1 HSP90B1 HSPA1A HSPA4 HSPA8 IK KRT1 POR RPL18 RPS3A SPTA1 SPTAN1 STAT1 TCERG1 USP14 ZBTB32
Entrez ID		3550	2176
HPRD ID		02771	01967
Ensembl ID		ENSG00000113141	ENSG00000158169
Uniprot IDs		Q13123 Q95HA6 Q9UK43	B4E3W2 Q00597
PDB IDs
Enriched GO Terms of Interacting Partners?		Viral Process MRNA Processing Positive Regulation Of Cellular Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway MRNA Metabolic Process RNA Processing RNA Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Protein Complex Assembly Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Viral Life Cycle Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Cell Death Death Nitrogen Compound Metabolic Process Chromatin Modification Regulation Of DNA-templated Transcription, Elongation Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Isotype Switching To IgA Isotypes Regulation Of Protein Tyrosine Kinase Activity Regulation Of Cellular Protein Metabolic Process Chromatin Organization Regulation Of Phosphorylation Positive Regulation Of Cellular Component Biogenesis Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Complex Assembly Cell Cycle RNA Splicing Negative Regulation Of Cellular Protein Metabolic Process Synaptic Growth At Neuromuscular Junction Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Positive Regulation Of CAMP Catabolic Process Regulation Of Protein Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Phosphorus Metabolic Process Signal Transduction In Response To DNA Damage Organelle Organization Regulation Of Cellular Amino Acid Metabolic Process	Protein Refolding Response To Unfolded Protein Cellular Response To Stress Regulation Of Cellular Response To Heat Response To Stress Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Heat DNA Repair Response To Stimulus Protein Import Into Mitochondrial Outer Membrane Response To Heat Protein Folding Response To Abiotic Stimulus Cellular Response To DNA Damage Stimulus Membrane Organization Cellular Metabolic Process Response To Organic Substance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Inclusion Body Assembly Response To Temperature Stimulus Axon Guidance Response To Oxidative Stress Response To External Stimulus Chaperone-mediated Protein Complex Assembly DNA Metabolic Process Establishment Of Protein Localization To Membrane Nucleobase-containing Compound Metabolic Process Chaperone Mediated Protein Folding Requiring Cofactor Regulation Of Apoptotic Process Cellular Response To Organonitrogen Compound Regulation Of Inclusion Body Assembly Regulation Of Cell Death Protein Localization To Organelle Female Gonad Development Axonogenesis Development Of Primary Female Sexual Characteristics Cellular Macromolecule Catabolic Process Viral Process Cellular Response To Peptide Hormone Stimulus Axon Development Positive Regulation Of Immune System Process Negative Regulation Of Apoptotic Process Cellular Response To Peptide Nitric Oxide Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Immune System Process Negative Regulation Of Programmed Cell Death Metabolic Process
Tagcloud ?		ach additive atrial circuit conductances coupling electrotonic gc input muscarinic node nonlinear oxford oxsoft pacemaker passive potassium potentiate potentiated prolongation rc sa simulation sinoatrial spontaneous stopped sufficiently surrounding uk	1beta autoinhibitory bm characterizes creating cytokines fanca fanconi hypersensitive inactivated leukemic loop mapkapk mononuclear multipotent overproduced overproduction p38 phagocytes posttranscriptionally potently progenitor progenitors progressive reasoning tlr toll transcriptionally
Tagcloud (Difference) ?		ach additive atrial circuit conductances coupling electrotonic gc input muscarinic node nonlinear oxford oxsoft pacemaker passive potassium potentiate potentiated prolongation rc sa simulation sinoatrial spontaneous stopped sufficiently surrounding uk	1beta autoinhibitory bm characterizes creating cytokines fanca fanconi hypersensitive inactivated leukemic loop mapkapk mononuclear multipotent overproduced overproduction p38 phagocytes posttranscriptionally potently progenitor progenitors progressive reasoning tlr toll transcriptionally
Tagcloud (Intersection) ?