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IK and NUP62
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
IK
NUP62
Description
IK cytokine
nucleoporin 62
Image
GO Annotations
Cellular Component
Nuclear Chromosome
Spindle Pole
Nucleus
Nucleoplasm
Spliceosomal Complex
Chromosome
Cytoplasm
Cytoskeleton
Nuclear Speck
U2-type Precatalytic Spliceosome
Mitotic Spindle Pole
Spindle Pole
Nucleus
Nuclear Envelope
Nuclear Pore
Nucleoplasm
Cytoplasm
Centrosome
Cytoskeleton
Nuclear Membrane
Nuclear Pore Central Transport Channel
Mitotic Spindle
Flemming Body
Ribonucleoprotein Complex
Molecular Function
Protein Binding
Identical Protein Binding
Chromatin Binding
Protein Binding
Phospholipid Binding
Structural Constituent Of Nuclear Pore
Signaling Receptor Complex Adaptor Activity
Hsp70 Protein Binding
SH2 Domain Binding
Ubiquitin Binding
PTB Domain Binding
Hsp90 Protein Binding
Biological Process
Mitotic Cell Cycle
MRNA Splicing, Via Spliceosome
MRNA Processing
Mitotic Spindle Assembly Checkpoint Signaling
RNA Splicing
Protein Localization To Kinetochore
RNA Export From Nucleus
Protein Import Into Nucleus
Nucleocytoplasmic Transport
Mitotic Metaphase Chromosome Alignment
Centrosome Cycle
Mitotic Centrosome Separation
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Cell Population Proliferation
Regulation Of Signal Transduction
Protein Transport
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Mitotic Nuclear Division
Positive Regulation Of DNA-templated Transcription
Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Centriole Replication
MRNA Transport
Regulation Of Mitotic Spindle Organization
Cellular Senescence
Centriole Assembly
Positive Regulation Of Mitotic Cytokinetic Process
Positive Regulation Of Protein Localization To Centrosome
Pathways
mRNA Splicing - Major Pathway
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
IPs transport between nucleus and cytosol
IP3 and IP4 transport between cytosol and nucleus
IP6 and IP7 transport between cytosol and nucleus
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS
Monocyte count (
32888494
)
Schizophrenia (
29483656
)
Serum immune biomarker levels (
32066700
)
Interacting Genes
28 interacting genes:
APP
CEBPA
CEP70
CHD3
CTNNBL1
DDX6
EGLN3
FANCC
FRA10AC1
FXR1
GRB2
KAT5
KDM1A
MBD3
MFAP1
NUP62
OGT
PFN2
QARS1
RACK1
RBM10
SUPT5H
THOC1
TOE1
TRIM55
TRIM63
TTC14
ZCCHC10
88 interacting genes:
ABI2
ADAM15
AGR3
ARFIP2
ATF7IP2
ATXN7
BFSP1
BLOC1S6
C14orf119
C1orf216
CAVIN3
CCDC121
CCDC146
CCDC150
CCHCR1
CENPU
CEP57L1
CLIC1
CRCT1
DDX3X
DGCR6
DPPA3
DRC12
DTNB
DYNLT1
FABP3
GOPC
GORASP2
GTF2E2
HAUS1
HGS
HSF2
HSF4
IDH1
IFT20
IFT25
IK
IKBIP
IPO5
ISCU
KANSL1
KIFC3
KLHL32
KPNA1
KPNA2
KPNB1
KRT1
KRT20
KRT3
KRT6A
KRT6B
KRT75
LMO2
LNX1
MUC1
MXD3
MYO15B
NUP153
NUP54
NUP58
NUP98
NUTF2
NXF1
NXF2
OGT
OIP5
OTUD6A
PBX2
PELI2
PIN1
PTMA
RANBP2
SMARCA2
SMARCE1
SNAPC5
SP1
SSC5D
SUOX
THAP1
TLE4
TRAF3
TRIML2
TXLNA
TXN
USHBP1
WASHC3
XPO1
XPO6
Entrez ID
3550
23636
HPRD ID
02771
05782
Ensembl ID
ENSG00000113141
ENSG00000213024
Uniprot IDs
Q13123
Q95HA6
Q9UK43
P37198
PDB IDs
5O9Z
6Q8I
8QO9
8QZS
5IJN
5IJO
7PER
7R5J
7R5K
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleus
PTB Domain Binding
Negative Regulation Of RNA Metabolic Process
Chromatin Binding
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of Biosynthetic Process
Nucleoplasm
Negative Regulation Of Metabolic Process
Positive Regulation Of Protein Metabolic Process
Apoptotic Process
Regulation Of Glycolytic Process
Programmed Cell Death
Macromolecule Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Cell Death
Regulation Of Programmed Cell Death
RNA Binding
Membraneless Organelle Assembly
Cellular Response To Glucose Stimulus
Regulation Of Carbohydrate Catabolic Process
Negative Regulation Of Long-term Synaptic Potentiation
Protein-containing Complex
Nucleic Acid Metabolic Process
Positive Regulation Of Proteolysis
Regulation Of ATP Metabolic Process
Positive Regulation Of Catabolic Process
Negative Regulation Of Gene Expression
Regulation Of Purine Nucleotide Metabolic Process
Regulation Of Apoptotic Process
Carbohydrate Homeostasis
Nucleobase-containing Compound Metabolic Process
RNA Metabolic Process
Glucose Homeostasis
Regulation Of Stem Cell Differentiation
NuRD Complex
Negative Regulation Of Translation
Nucleic Acid Binding
MRNA Splicing, Via Spliceosome
RNA Splicing
Cellular Response To Carbohydrate Stimulus
Positive Regulation Of RNA Metabolic Process
Post-transcriptional Regulation Of Gene Expression
RNA Splicing, Via Transesterification Reactions
Positive Regulation Of Metabolic Process
Translation Regulator Activity
Intracellular Glucose Homeostasis
Nuclear Transport
Nucleocytoplasmic Transport
Nuclear Localization Sequence Binding
Nuclear Pore
NLS-bearing Protein Import Into Nucleus
RNA Transport
Protein Import Into Nucleus
Import Into Nucleus
Nuclear Export
MRNA Transport
Intracellular Transport
Nuclear Import Signal Receptor Activity
Protein Localization To Nucleus
Protein Transport
Establishment Of Protein Localization
Structural Constituent Of Nuclear Pore
Intermediate Filament Organization
Nuclear Membrane
Nucleobase-containing Compound Transport
Nuclear Inclusion Body
Protein Binding
Intermediate Filament Cytoskeleton Organization
Structural Constituent Of Skin Epidermis
Intermediate Filament-based Process
Intracellular Protein Transport
Cellular Localization
Protein Localization To Organelle
Establishment Of Localization In Cell
Establishment Of Protein Localization To Organelle
Supramolecular Fiber Organization
Nuclear Envelope
Intracellular Protein Localization
Intracellular Transport Of Virus
Keratin Filament
Host Cell
NLS-dependent Protein Nuclear Import Complex
Cytoskeleton Organization
Small GTPase Binding
Intermediate Filament
Protein Export From Nucleus
Keratinization
Nuclear Pore Nuclear Basket
Regulation Of Nucleocytoplasmic Transport
Nuclear Pore Organization
Identical Protein Binding
RNA Export From Nucleus
Nucleus Organization
Organelle Organization
Ribosomal Protein Import Into Nucleus
Viral Penetration Into Host Nucleus
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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