FAS and CASP8

  • Number of citations of the paper that reports this interaction (PMID 11101867)
  • 60
  • Data Source:
  • HPRD (in vivo)

FAS

CASP8

Gene Name Fas cell surface death receptor caspase 8, apoptosis-related cysteine peptidase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 48 interactors: ANK3 APAF1 APOA5 ATP6V0B BAG6 BTK C14orf1 CALM1 CASP8 CASP8AP2 CCND3 CD47 CRMP1 DAXX EEF1A1 EGFR EZR FADD FAF1 FAF2 FAIM2 FASLG FBF1 FEM1B FYN GADD45A HIPK3 HNRNPC KRIT1 LCK LRIF1 MBD4 MET PDCD6 PRKCA PTPN13 PTPN6 RAP1A RIPK1 SUMO1 TCAP TMX1 TNFSF13 TRADD TRAF3 UBA7 UBE2I UBQLN1 91 interactors: APAF1 APP AR ATG4D BCAP31 BCL2 BCL2L1 BFAR BID BIRC6 CASP1 CASP10 CASP14 CASP2 CASP3 CASP4 CASP6 CASP7 CASP8AP2 CASP9 CDH1 CDK11B CDKN1B CFLAR CHD3 CHUK COPS6 CRADD CTNNB1 DEDD DEDD2 EDA2R EIF2AK2 FADD FAF1 FAS FYN GMEB1 GRIA1 GZMB HDAC7 HECTD3 HIP1 IKBKB IKBKG ILK KRT18 MAP1LC3B MAP3K14 MAP4K4 MAPK1 MAPK3 MAPT NOD1 NOL3 NR1H4 PARK2 PARK7 PARP1 PARP2 PCYT1A PDIA6 PEA15 PIAS1 PICALM PLA2G4B PLEC PLIN4 PRDX6 PRKCI PRKCZ PSEN1 PSEN2 RALBP1 RB1 RIPK1 RIPK2 RYBP SNRPD3 SRF STK24 SUMO1 TFCP2 TNFRSF10A TNFRSF10B TOPORS TRAF1 TRAF2 TRAF6 USO1 VIM
Entrez ID 355 841
HPRD ID 00609 03459
Ensembl ID ENSG00000026103 ENSG00000064012
Uniprot IDs P25445 Q14790
PDB IDs 1BZI 1DDF 3EWT 3EZQ 3THM 3TJE 1F9E 1I4E 1QDU 1QTN 2C2Z 2FUN 2K7Z 2Y1L 3H11 3KJN 3KJQ 4JJ7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
activities  auto  catalytically  constitute  constitutive  constitutively  construct  constructs  deleted  ds  dsrna  egfp  fusion  green  inactive  inducible  jellyfish  pkr  possess  possessed  protected  serine  stranded  substitution  sufficient  threonine  transfection  tumorigenic  visualize 
10mum  abeta42  abeta43  aif  carnosic  cascades  casp3  casp4  casp9  casps  concurrently  diterpene  herbs  ingestion  initiator  labiate  monomer  neurotoxicity  neurotrophic  oligomerization  oligomers  parp  phenolic  ribose  rosemary  sage  serves  sy5y 
Tagcloud (Difference) ?
activities  auto  catalytically  constitute  constitutive  constitutively  construct  constructs  deleted  ds  dsrna  egfp  fusion  green  inactive  inducible  jellyfish  pkr  possess  possessed  protected  serine  stranded  substitution  sufficient  threonine  transfection  tumorigenic  visualize 
10mum  abeta42  abeta43  aif  carnosic  cascades  casp3  casp4  casp9  casps  concurrently  diterpene  herbs  ingestion  initiator  labiate  monomer  neurotoxicity  neurotrophic  oligomerization  oligomers  parp  phenolic  ribose  rosemary  sage  serves  sy5y 
Tagcloud (Intersection) ?