LCE2D and GLRX3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LCE2D	GLRX3
Gene Name		late cornified envelope 2D	glutaredoxin 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Cell Cortex Z Disc Extracellular Vesicular Exosome
	Molecular Function		Protein Kinase C Binding Protein Binding Electron Carrier Activity Protein Disulfide Oxidoreductase Activity Poly(A) RNA Binding Metal Ion Binding Iron-sulfur Cluster Binding
	Biological Process	Keratinization	Regulation Of The Force Of Heart Contraction Negative Regulation Of Cardiac Muscle Hypertrophy Cell Redox Homeostasis Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS			HIV-1 susceptibility ( 21160409)
Protein-Protein Interactions		14 interactors: ADAMTSL4 EFEMP2 GLRX3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 NOTCH2NL OTX1 PLSCR1 RGS20 SPRY1 SPRY2 SUMO1P1	57 interactors: ADAMTSL4 ALKBH3 BOLA1 CBLB CGGBP1 CIAPIN1 EFEMP2 FAM118A FRA10AC1 GMCL1 GRN HEXDC IKZF1 KRT31 KRT38 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP13-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE2D MAP3K3 MAPK6 MAPKBP1 MOXD1 NADK NOTCH2NL OLFM3 PCSK5 PFDN5 PLSCR1 PRKCQ PRKCZ PRKD2 RGS20 SOX7 STAU1 TCF4 TMEM25 TRAF1 TRIM36 TRIM42 UGP2 ZBTB44 ZNF148 ZNF426 ZNF512B ZNF544
Entrez ID		353141	10539
HPRD ID		17261	10153
Ensembl ID		ENSG00000187223	ENSG00000108010
Uniprot IDs		Q5TA82	O76003
PDB IDs			2DIY 2WZ9 2YAN 3ZYW
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Neurotrophin TRK Receptor Signaling Pathway Bud Elongation Involved In Lung Branching Negative Regulation Of Ras GTPase Activity Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Branch Elongation Of An Epithelium Negative Regulation Of GTPase Activity Axis Elongation Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Establishment Of Mitotic Spindle Orientation Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Epithelial Tube Branching Involved In Lung Morphogenesis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Spindle Localization Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Lung Morphogenesis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Negative Regulation Of MAP Kinase Activity Inner Ear Morphogenesis Negative Regulation Of Cellular Response To Growth Factor Stimulus Establishment Of Cell Polarity Ear Morphogenesis Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Negative Regulation Of Protein Serine/threonine Kinase Activity Developmental Growth Involved In Morphogenesis Negative Regulation Of MAPK Cascade Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Establishment Or Maintenance Of Cell Polarity Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Cellular Process Phosphatidylserine Biosynthetic Process Inner Ear Development Regulation Of ERK1 And ERK2 Cascade Diencephalon Morphogenesis Branching Morphogenesis Of An Epithelial Tube Regulation Of GTPase Activity Negative Regulation Of Protein Kinase Activity Lung Growth Negative Regulation Of Kinase Activity Ear Development Morphogenesis Of A Branching Epithelium Lung Development Morphogenesis Of A Branching Structure Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway	Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Developmental Process Positive Regulation Of Interleukin-4 Production Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Interleukin-4 Production Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation Regulation Of Cell Activation Regulation Of T Cell Activation Cell Death Death Multicellular Organismal Development Positive Regulation Of Interleukin-2 Production Positive Regulation Of Alpha-beta T Cell Differentiation Positive Regulation Of Epithelial Cell Proliferation Anatomical Structure Development Positive Regulation Of Neutrophil Differentiation Renin Secretion Into Blood Stream Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Cellular Process Transcription, DNA-templated Regulation Of T Cell Receptor Signaling Pathway Embryonic Digestive Tract Development Positive Regulation Of Immune System Process Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Cell Adhesion Positive Regulation Of Protein Metabolic Process Regulation Of Signal Transduction RNA Biosynthetic Process Regulation Of Lymphocyte Activation Protein Kinase D Signaling Positive Regulation Of T-helper 2 Cell Activation Oxidative Single-stranded DNA Demethylation Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Renal Response To Blood Flow Involved In Circulatory Renin-angiotensin Regulation Of Systemic Arterial Blood Pressure Platelet Activation Regulation Of Insulin Receptor Signaling Pathway Apoptotic Process Positive Regulation Of T Cell Activation
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