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IFNA1 and IRF9
Number of citations of the paper that reports this interaction (PubMedID
8454630
)
0
Data Source:
HPRD
(in vitro)
IFNA1
IRF9
Description
interferon alpha 1
interferon regulatory factor 9
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
ISGF3 Complex
Molecular Function
Cytokine Activity
Cytokine Receptor Binding
Type I Interferon Receptor Binding
Protein Binding
Transcription Cis-regulatory Region Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Adaptive Immune Response
T Cell Activation Involved In Immune Response
B Cell Activation Involved In Immune Response
Natural Killer Cell Activation Involved In Immune Response
Defense Response
Humoral Immune Response
Response To Exogenous DsRNA
Symbiont Entry Into Host Cell
Defense Response To Virus
Type I Interferon-mediated Signaling Pathway
Cellular Response To Virus
Antiviral Innate Immune Response
Immune System Process
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Transcription By RNA Polymerase II
Defense Response To Virus
Pathways
Interferon alpha/beta signaling
Regulation of IFNA/IFNB signaling
Regulation of IFNA/IFNB signaling
TRAF6 mediated IRF7 activation
SARS-CoV-2 activates/modulates innate and adaptive immune responses
Factors involved in megakaryocyte development and platelet production
Evasion by RSV of host interferon responses
Interferon gamma signaling
Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Interacting Genes
4 interacting genes:
CR2
IFNAR1
IL2
IRF9
20 interacting genes:
ARID3B
DACH2
DMRTC2
HOXC9
IFNA1
ILF3
IRF1
IRF2BP1
MYO1F
NFKB1
NR2E3
POU2F1
RELA
S100A13
STAT1
STAT2
TLX2
TLX3
TOP1
VENTX
Entrez ID
3439
10379
HPRD ID
00974
00960
Ensembl ID
ENSG00000197919
ENSG00000213928
Uniprot IDs
L0N195
P01562
A0A8V8TMJ8
A0A8V8TP83
H0YNP4
Q00978
PDB IDs
3UX9
Enriched GO Terms of Interacting Partners
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Type I Interferon-mediated Signaling Pathway
Cytokine-mediated Signaling Pathway
Response To Virus
Interferon-mediated Signaling Pathway
Negative Regulation Of Adaptive Immune Response
Glycine Dehydrogenase (decarboxylating) Activity
Pyridoxal Binding
Response To Methylamine
Cell Surface Receptor Signaling Pathway Via STAT
Kappa-type Opioid Receptor Binding
Lymphocyte Proliferation
Leukocyte Proliferation
Cell Surface Receptor Signaling Pathway
Mononuclear Cell Proliferation
Glycine Decarboxylation Via Glycine Cleavage System
Response To Lipoic Acid
Glycine Cleavage Complex
Glycine Catabolic Process
Type I Interferon Receptor Activity
Type I Interferon Binding
JAK Pathway Signal Transduction Adaptor Activity
Interferon Receptor Activity
Regulation Of T Cell Homeostatic Proliferation
Response To Tacrolimus
ISGF3 Complex
Positive Regulation Of Plasma Cell Differentiation
Receptor Complex
Regulation Of Lymphocyte Mediated Immunity
Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Interleukin-2 Receptor Binding
Negative Regulation Of Immune Response
Regulation Of Adaptive Immune Response
Glycosphingolipid Binding
Complement Binding
Negative Regulation Of Complement Activation, Classical Pathway
Lymphocyte Differentiation
Complement Receptor Activity
Response To Other Organism
Activated T Cell Proliferation
Adaptive Immune Response
Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin
Defense Response To Virus
Glycine Binding
Cellular Response To Interferon-alpha
Transcription By RNA Polymerase II
Positive Regulation Of Isotype Switching To IgG Isotypes
Response To External Biotic Stimulus
Negative Regulation Of Complement Activation
Mononuclear Cell Differentiation
Complement Receptor Mediated Signaling Pathway
DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Sequence-specific DNA Binding
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Chromatin
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Response To Virus
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Nucleus
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Primary Metabolic Process
Defense Response To Virus
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Biosynthetic Process
NF-kappaB P50/p65 Complex
Interferon-mediated Signaling Pathway
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
Positive Regulation Of RNA Metabolic Process
Nucleoplasm
ISGF3 Complex
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Cytokine-mediated Signaling Pathway
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Biosynthetic Process
Negative Regulation Of RNA Metabolic Process
Response To Peptide Hormone
Transcription Coactivator Binding
Type I Interferon-mediated Signaling Pathway
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Cellular Response To Nicotine
Tumor Necrosis Factor-mediated Signaling Pathway
Cellular Response To Peptide Hormone Stimulus
Regulation Of Interleukin-12 Production
Positive Regulation Of MiRNA Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Response To Mechanical Stimulus
Actinin Binding
DNA-templated Transcription
Type II Interferon-mediated Signaling Pathway
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Tagcloud (Intersection)
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