IRF9 and ARID3B

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		IRF9	ARID3B
Gene Name		interferon regulatory factor 9	AT rich interactive domain 3B (BRIGHT-like)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm
	Molecular Function	Regulatory Region DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Type I Interferon Biosynthetic Process Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway	Transcription, DNA-templated Biological_process Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Diastolic blood pressure ( 19430483)
Protein-Protein Interactions		19 interactors: ARID3B DACH2 DMRTC2 HOXC9 IFNA1 IRF1 IRF2BP1 MYO1F NFKB1 NR2E3 POU2F1 RELA S100A13 STAT1 STAT2 TLX2 TLX3 TOP1 VENTX	5 interactors: APP IRF9 POT1 RB1 TINF2
Entrez ID		10379	10620
HPRD ID		00960	09806
Ensembl ID		ENSG00000213928	ENSG00000179361
Uniprot IDs		Q00978	Q8IVW6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Innate Immune Response Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Interleukin-12 Biosynthetic Process RNA Metabolic Process Defense Response To Virus Gene Expression Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Other Organism Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Response To Biotic Stimulus Cellular Nitrogen Compound Metabolic Process Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Virus Response To Type I Interferon Regulation Of Immune Response Transcription From RNA Polymerase II Promoter Immune Response Cellular Response To Cytokine Stimulus Nitrogen Compound Metabolic Process Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Response To Cytokine Regulation Of Interleukin-12 Production Cellular Response To Nicotine Cytokine-mediated Signaling Pathway Response To Mechanical Stimulus Innate Immune Response Positive Regulation Of Type I Interferon Production Developmental Process Regulation Of MiRNA Metabolic Process Response To External Stimulus Regulation Of Immune System Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Assembly Negative Regulation Of Telomere Maintenance Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Regulation Of Chromosome Organization Protein Localization To Chromosome Neuron Maturation Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Replication Positive Regulation Of Organelle Organization Positive Regulation Of Mitotic Cell Cycle Phase Transition Homeostatic Process Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Neuron Death Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of DNA Strand Elongation Positive Regulation Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of DNA Replication Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Catalytic Activity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of DNA Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Cell Maturation Regulation Of Protein ADP-ribosylation Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Synaptic Growth At Neuromuscular Junction Sister Chromatid Biorientation Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Organelle Organization Collateral Sprouting In Absence Of Injury Regulation Of Centromere Complex Assembly Telomere Formation Via Telomerase Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Intracellular Receptor Signaling Pathway Nitrogen Compound Metabolic Process Chromosome Organization Maintenance Of Mitotic Sister Chromatid Cohesion
Tagcloud ?		antiviral attenuated defense enhancement essential failed guanylate iav ifn impaired induces inducible infection influenza interference interferon isg15 isg20 isgs knockdown knocked oligoadenylate p53 pretreatment replication retinoic secretion synthetase	125b acvr1b acvr2a bak1 bcl2l2 bear bim bmpr1b cadm1 cardio cardiology cmass e2f3 fgfr2 fgfr3 glut3 il6r jph2 men1 mirs onco orchestration raf1 sitr7 smoothened st7l twist1 wee1 wnt7a
Tagcloud (Difference) ?		antiviral attenuated defense enhancement essential failed guanylate iav ifn impaired induces inducible infection influenza interference interferon isg15 isg20 isgs knockdown knocked oligoadenylate p53 pretreatment replication retinoic secretion synthetase	125b acvr1b acvr2a bak1 bcl2l2 bear bim bmpr1b cadm1 cardio cardiology cmass e2f3 fgfr2 fgfr3 glut3 il6r jph2 men1 mirs onco orchestration raf1 sitr7 smoothened st7l twist1 wee1 wnt7a
Tagcloud (Intersection) ?