IRF9 and IRF2BP1

Number of citations of the paper that reports this interaction (PMID 12799427)
18

Data Source:
BioGRID (two hybrid)

		IRF9	IRF2BP1
Gene Name		interferon regulatory factor 9	interferon regulatory factor 2 binding protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleoplasm Aggresome Intracellular Membrane-bounded Organelle
	Molecular Function	Regulatory Region DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding	Protein Binding Ligase Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Type I Interferon Biosynthetic Process Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ARID3B DACH2 DMRTC2 HOXC9 IFNA1 IRF1 IRF2BP1 MYO1F NFKB1 NR2E3 POU2F1 RELA S100A13 STAT1 STAT2 TLX2 TLX3 TOP1 VENTX	7 interactors: ATF2 IRF2 IRF9 JDP2 PCBD2 SMAD1 TGIF1
Entrez ID		10379	26145
HPRD ID		00960	17159
Ensembl ID		ENSG00000213928	ENSG00000170604
Uniprot IDs		Q00978	Q8IU81
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Innate Immune Response Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Interleukin-12 Biosynthetic Process RNA Metabolic Process Defense Response To Virus Gene Expression Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Other Organism Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Response To Biotic Stimulus Cellular Nitrogen Compound Metabolic Process Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Virus Response To Type I Interferon Regulation Of Immune Response Transcription From RNA Polymerase II Promoter Immune Response Cellular Response To Cytokine Stimulus Nitrogen Compound Metabolic Process Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Response To Cytokine Regulation Of Interleukin-12 Production Cellular Response To Nicotine Cytokine-mediated Signaling Pathway Response To Mechanical Stimulus Innate Immune Response Positive Regulation Of Type I Interferon Production Developmental Process Regulation Of MiRNA Metabolic Process Response To External Stimulus Regulation Of Immune System Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Positive Regulation Of Transcription, DNA-templated	Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Defense Response Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Type I Interferon Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Interferon-gamma-mediated Signaling Pathway Positive Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Cellular Biosynthetic Process Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Interferon-gamma Positive Regulation Of Metabolic Process Response To Interferon-gamma Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Cellular Response To Transforming Growth Factor Beta Stimulus Innate Immune Response Response To Transforming Growth Factor Beta Primary MiRNA Processing MAPK Cascade Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Connective Tissue Development Osteoblast Fate Commitment Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Transcription From RNA Polymerase II Promoter Tetrahydrobiopterin Biosynthetic Process
Tagcloud ?		antiviral attenuated defense enhancement essential failed guanylate iav ifn impaired induces inducible infection influenza interference interferon isg15 isg20 isgs knockdown knocked oligoadenylate p53 pretreatment replication retinoic secretion synthetase	abundance collection colorectal dataset dissected front give healing igf1 immunohistochemical individually insights invasion knockout largest lymph lymphatic mx1 node nonmetastatic overexpressed phenotypes proteome quantified representing resolution validation wilcoxon wound
Tagcloud (Difference) ?		antiviral attenuated defense enhancement essential failed guanylate iav ifn impaired induces inducible infection influenza interference interferon isg15 isg20 isgs knockdown knocked oligoadenylate p53 pretreatment replication retinoic secretion synthetase	abundance collection colorectal dataset dissected front give healing igf1 immunohistochemical individually insights invasion knockout largest lymph lymphatic mx1 node nonmetastatic overexpressed phenotypes proteome quantified representing resolution validation wilcoxon wound
Tagcloud (Intersection) ?