IRF9 and IRF2BP1

Number of citations of the paper that reports this interaction (PubMedID 12799427)
59

Data Source:
BioGRID (two hybrid)

		IRF9	IRF2BP1
Description		interferon regulatory factor 9	interferon regulatory factor 2 binding protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol ISGF3 Complex	Nucleus Nucleoplasm
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Immune System Process Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Cell Surface Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus	Negative Regulation Of Transcription By RNA Polymerase II Protein Polyubiquitination Regulation Of Transcription By RNA Polymerase II
Pathways		Interferon gamma signaling Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Asthma ( 31959851) Gallstone disease ( 30504769) HDL cholesterol levels ( 32203549) Mean corpuscular hemoglobin ( 32888494)
Interacting Genes		20 interacting genes: ARID3B DACH2 DMRTC2 HOXC9 IFNA1 ILF3 IRF1 IRF2BP1 MYO1F NFKB1 NR2E3 POU2F1 RELA S100A13 STAT1 STAT2 TLX2 TLX3 TOP1 VENTX	9 interacting genes: ATF2 CEBPA IRF2 IRF9 JDP2 PCBD2 SMAD1 TGIF1 UBE2L3
Entrez ID		10379	26145
HPRD ID		00960	17159
Ensembl ID		ENSG00000213928	ENSG00000170604
Uniprot IDs		A0A8V8TMJ8 A0A8V8TP83 H0YNP4 Q00978	Q8IU81
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Chromatin Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Response To Virus DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Nucleus Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Defense Response To Virus Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process NF-kappaB P50/p65 Complex Interferon-mediated Signaling Pathway RNA Polymerase II Core Promoter Sequence-specific DNA Binding Positive Regulation Of RNA Metabolic Process Nucleoplasm ISGF3 Complex Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cytokine-mediated Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of RNA Metabolic Process Response To Peptide Hormone Transcription Coactivator Binding Type I Interferon-mediated Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Nicotine Tumor Necrosis Factor-mediated Signaling Pathway Cellular Response To Peptide Hormone Stimulus Regulation Of Interleukin-12 Production Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Response To Mechanical Stimulus Actinin Binding DNA-templated Transcription Type II Interferon-mediated Signaling Pathway	DNA-binding Transcription Factor Activity RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cell Population Proliferation Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Sequence-specific Double-stranded DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA Binding Regulation Of Primary Metabolic Process Leucine Zipper Domain Binding CAMP Response Element Binding Co-SMAD Binding Fat Cell Differentiation White Fat Cell Differentiation Regulation Of Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Transcription Regulator Complex DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Chromatin Binding Regulation Of Metabolic Process Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription Cis-regulatory Region Binding Positive Regulation Of Metabolic Process Negative Regulation Of RNA Metabolic Process Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Abducens Nucleus Development Hypoglossal Nucleus Development Protein Heterodimerization Activity Positive Regulation Of Osteoblast Differentiation Nucleobase-containing Compound Biosynthetic Process
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