IRF9 and S100A13

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		IRF9	S100A13
Gene Name		interferon regulatory factor 9	S100 calcium binding protein A13
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Extracellular Space Nucleus Cytoplasm Cytosol Mast Cell Granule Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Regulatory Region DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding	Copper Ion Binding Calcium Ion Binding Protein Binding Zinc Ion Binding Lipid Binding Fibroblast Growth Factor Binding Protein Homodimerization Activity RAGE Receptor Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Type I Interferon Biosynthetic Process Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway	Positive Regulation Of Cell Proliferation Regulation Of Cell Shape Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Mast Cell Degranulation Response To Copper Ion Cytokine Secretion Interleukin-1 Alpha Secretion Response To Electrical Stimulus
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs			Olopatadine Amlexanox
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ARID3B DACH2 DMRTC2 HOXC9 IFNA1 IRF1 IRF2BP1 MYO1F NFKB1 NR2E3 POU2F1 RELA S100A13 STAT1 STAT2 TLX2 TLX3 TOP1 VENTX	7 interactors: FGF1 IGBP1 IL1A IRF9 PHYHIP PLEKHF2 SYT1
Entrez ID		10379	6284
HPRD ID		00960	03586
Ensembl ID		ENSG00000213928	ENSG00000189171
Uniprot IDs		Q00978	Q99584
PDB IDs			1YUR 1YUS 1YUT 1YUU 2EGD 2H2K 2K8M 2KI4 2KI6 2KOT 2L5X 2LE9
Enriched GO Terms of Interacting Partners?		Regulation Of Innate Immune Response Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Interleukin-12 Biosynthetic Process RNA Metabolic Process Defense Response To Virus Gene Expression Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Other Organism Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Response To Biotic Stimulus Cellular Nitrogen Compound Metabolic Process Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Virus Response To Type I Interferon Regulation Of Immune Response Transcription From RNA Polymerase II Promoter Immune Response Cellular Response To Cytokine Stimulus Nitrogen Compound Metabolic Process Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Response To Cytokine Regulation Of Interleukin-12 Production Cellular Response To Nicotine Cytokine-mediated Signaling Pathway Response To Mechanical Stimulus Innate Immune Response Positive Regulation Of Type I Interferon Production Developmental Process Regulation Of MiRNA Metabolic Process Response To External Stimulus Regulation Of Immune System Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Positive Regulation Of Transcription, DNA-templated	Cellular Response To Heat Branch Elongation Involved In Ureteric Bud Branching Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter Response To Heat Regulation Of MAPK Cascade Positive Regulation Of Angiogenesis Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Cell Division Response To Cytokine Immune System Process Regulation Of Stress-activated MAPK Cascade Response To Temperature Stimulus Regulation Of ERK1 And ERK2 Cascade Fever Generation Calcium Ion-dependent Exocytosis Of Neurotransmitter Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Ureteric Bud Elongation Regulation Of Angiogenesis Negative Regulation Of Protein Dephosphorylation Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Organic Substance Heat Generation Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Cell Division Wound Healing Involved In Inflammatory Response Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Cholesterol Metabolic Process Positive Regulation Of Secretion Response To Metal Ion Type I Interferon Biosynthetic Process Immune Response Regulation Of Phosphorylation Detection Of Calcium Ion Positive Regulation Of Transcription, DNA-templated Defense Response Regulation Of Signaling Ectopic Germ Cell Programmed Cell Death Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Microtubule-based Movement Signaling Positive Regulation Of Interleukin-2 Biosynthetic Process Cell Communication Type I Interferon Production Positive Regulation Of Organelle Organization Regulation Of Phosphorus Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Vesicle Fusion Positive Regulation Of Gene Expression Positive Regulation Of MAPK Cascade
Tagcloud ?		antiviral attenuated defense enhancement essential failed guanylate iav ifn impaired induces inducible infection influenza interference interferon isg15 isg20 isgs knockdown knocked oligoadenylate p53 pretreatment replication retinoic secretion synthetase	anchor bilayer biophysical biphasic c2b calorimetry cu2 destabilized endothermic exothermic fgf1 isothermal itc lacks marginally mrc multiprotein nonclassical p40 phosphatidyl pockets proangiogenic ps synaptotagmin syt1 tb3 titration unilamellar vesicles
Tagcloud (Difference) ?		antiviral attenuated defense enhancement essential failed guanylate iav ifn impaired induces inducible infection influenza interference interferon isg15 isg20 isgs knockdown knocked oligoadenylate p53 pretreatment replication retinoic secretion synthetase	anchor bilayer biophysical biphasic c2b calorimetry cu2 destabilized endothermic exothermic fgf1 isothermal itc lacks marginally mrc multiprotein nonclassical p40 phosphatidyl pockets proangiogenic ps synaptotagmin syt1 tb3 titration unilamellar vesicles
Tagcloud (Intersection) ?