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IFNA1
Description
interferon alpha 1
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Molecular Function
Cytokine Activity
Cytokine Receptor Binding
Type I Interferon Receptor Binding
Protein Binding
Biological Process
Adaptive Immune Response
T Cell Activation Involved In Immune Response
B Cell Activation Involved In Immune Response
Natural Killer Cell Activation Involved In Immune Response
Defense Response
Humoral Immune Response
Response To Exogenous DsRNA
Symbiont Entry Into Host Cell
Defense Response To Virus
Type I Interferon-mediated Signaling Pathway
Cellular Response To Virus
Antiviral Innate Immune Response
Pathways
Interferon alpha/beta signaling
Regulation of IFNA/IFNB signaling
Regulation of IFNA/IFNB signaling
TRAF6 mediated IRF7 activation
SARS-CoV-2 activates/modulates innate and adaptive immune responses
Factors involved in megakaryocyte development and platelet production
Evasion by RSV of host interferon responses
Drugs
Diseases
GWAS
Novel Interacting Genes
1 novel interacting genes:
GLDC
Interacting Genes
4 interacting genes:
CR2
IFNAR1
IL2
IRF9
Entrez ID
3439
HPRD ID
00974
Ensembl ID
ENSG00000197919
Uniprot IDs
L0N195
P01562
PDB IDs
3UX9
Enriched GO Terms of Interacting Partners
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Type I Interferon-mediated Signaling Pathway
Cytokine-mediated Signaling Pathway
Response To Virus
Interferon-mediated Signaling Pathway
Negative Regulation Of Adaptive Immune Response
Glycine Dehydrogenase (decarboxylating) Activity
Pyridoxal Binding
Response To Methylamine
Cell Surface Receptor Signaling Pathway Via STAT
Kappa-type Opioid Receptor Binding
Lymphocyte Proliferation
Leukocyte Proliferation
Cell Surface Receptor Signaling Pathway
Mononuclear Cell Proliferation
Glycine Decarboxylation Via Glycine Cleavage System
Response To Lipoic Acid
Glycine Cleavage Complex
Glycine Catabolic Process
Type I Interferon Receptor Activity
Type I Interferon Binding
JAK Pathway Signal Transduction Adaptor Activity
Interferon Receptor Activity
Regulation Of T Cell Homeostatic Proliferation
Response To Tacrolimus
ISGF3 Complex
Positive Regulation Of Plasma Cell Differentiation
Receptor Complex
Regulation Of Lymphocyte Mediated Immunity
Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Interleukin-2 Receptor Binding
Negative Regulation Of Immune Response
Regulation Of Adaptive Immune Response
Glycosphingolipid Binding
Complement Binding
Negative Regulation Of Complement Activation, Classical Pathway
Lymphocyte Differentiation
Complement Receptor Activity
Response To Other Organism
Activated T Cell Proliferation
Adaptive Immune Response
Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin
Defense Response To Virus
Glycine Binding
Cellular Response To Interferon-alpha
Transcription By RNA Polymerase II
Positive Regulation Of Isotype Switching To IgG Isotypes
Response To External Biotic Stimulus
Negative Regulation Of Complement Activation
Mononuclear Cell Differentiation
Complement Receptor Mediated Signaling Pathway
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