IRF9 and VENTX

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		IRF9	VENTX
Gene Name		interferon regulatory factor 9	VENT homeobox
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus
	Molecular Function	Regulatory Region DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding	Sequence-specific DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Type I Interferon Biosynthetic Process Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway	Regulation Of Transcription, DNA-templated Multicellular Organismal Development
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ARID3B DACH2 DMRTC2 HOXC9 IFNA1 IRF1 IRF2BP1 MYO1F NFKB1 NR2E3 POU2F1 RELA S100A13 STAT1 STAT2 TLX2 TLX3 TOP1 VENTX	10 interactors: C1orf94 DAB1 IRF9 KRTAP12-2 KRTAP12-4 RBPMS TBX15 TBX22 TLE1 TLE2
Entrez ID		10379	27287
HPRD ID		00960	06197
Ensembl ID		ENSG00000213928	ENSG00000151650
Uniprot IDs		Q00978	O95231
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Innate Immune Response Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Interleukin-12 Biosynthetic Process RNA Metabolic Process Defense Response To Virus Gene Expression Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Other Organism Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Response To Biotic Stimulus Cellular Nitrogen Compound Metabolic Process Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Virus Response To Type I Interferon Regulation Of Immune Response Transcription From RNA Polymerase II Promoter Immune Response Cellular Response To Cytokine Stimulus Nitrogen Compound Metabolic Process Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Response To Cytokine Regulation Of Interleukin-12 Production Cellular Response To Nicotine Cytokine-mediated Signaling Pathway Response To Mechanical Stimulus Innate Immune Response Positive Regulation Of Type I Interferon Production Developmental Process Regulation Of MiRNA Metabolic Process Response To External Stimulus Regulation Of Immune System Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Positive Regulation Of Transcription, DNA-templated	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cerebellum Structural Organization Notch Signaling Pathway Lateral Motor Column Neuron Migration Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Spinal Cord Motor Neuron Migration Negative Regulation Of Wnt Signaling Pathway Radial Glia Guided Migration Of Purkinje Cell Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Organ Morphogenesis Wnt Signaling Pathway Negative Regulation Of Signal Transduction Anatomical Structure Morphogenesis Type I Interferon Biosynthetic Process Regulation Of Wnt Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of SMAD Protein Import Into Nucleus Golgi Localization Negative Regulation Of Anoikis Multicellular Organismal Development Type I Interferon Production Negative Regulation Of Astrocyte Differentiation Regulation Of Signal Transduction Regulation Of SMAD Protein Import Into Nucleus Regulation Of Anoikis
Tagcloud ?		antiviral attenuated defense enhancement essential failed guanylate iav ifn impaired induces inducible infection influenza interference interferon isg15 isg20 isgs knockdown knocked oligoadenylate p53 pretreatment replication retinoic secretion synthetase	challenge clonogenicity engraftment ex expansion helped hematopoietic homeobox hsc il2rgamma2 implicated intensive intrinsic investigations mechanistically mpp mpps multipotent nevertheless null ontogenesis pools preserve progenitor regulators scid strikingly suppression wnt
Tagcloud (Difference) ?		antiviral attenuated defense enhancement essential failed guanylate iav ifn impaired induces inducible infection influenza interference interferon isg15 isg20 isgs knockdown knocked oligoadenylate p53 pretreatment replication retinoic secretion synthetase	challenge clonogenicity engraftment ex expansion helped hematopoietic homeobox hsc il2rgamma2 implicated intensive intrinsic investigations mechanistically mpp mpps multipotent nevertheless null ontogenesis pools preserve progenitor regulators scid strikingly suppression wnt
Tagcloud (Intersection) ?