ZSCAN22 and ZNF446

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		ZSCAN22	ZNF446
Description		zinc finger and SCAN domain containing 22	zinc finger protein 446
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Extracellular Space Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Uric acid clearance ( 28095793)
Interacting Genes		29 interacting genes: BYSL CDR2L DVL3 KCTD19 NEXN PGBD1 PRPF31 SERTAD2 TLK1 ZGPAT ZKSCAN4 ZKSCAN7 ZNF174 ZNF24 ZNF263 ZNF397 ZNF444 ZNF446 ZNF449 ZNF483 ZNF496 ZSCAN1 ZSCAN16 ZSCAN18 ZSCAN21 ZSCAN23 ZSCAN25 ZSCAN32 ZSCAN9	54 interacting genes: ACTN2 ANKRD1 CCNK COPS2 CYSRT1 DGCR6 DGCR6L EHMT2 EVI5 FHL5 FRMD8 FRS3 GOLGA6L9 INCA1 KIFC3 KRT31 KRT34 KRT35 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP3-1 LNX1 LZTS2 MAGOHB MDFI NBPF19 NOTCH2NLA PIN1 REL SCAND1 SIVA1 SUFU TAX1BP1 TRIM27 UBE2I UBE3A ZKSCAN7 ZNF165 ZNF18 ZNF232 ZNF24 ZNF263 ZNF496 ZSCAN12 ZSCAN16 ZSCAN18 ZSCAN21 ZSCAN22 ZSCAN29 ZSCAN30 ZSCAN32 ZSCAN9
Entrez ID		342945	55663
HPRD ID		01315	07934
Ensembl ID		ENSG00000182318	ENSG00000083838
Uniprot IDs		P10073	Q9NWS9
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Metal Ion Binding Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Sequence-specific DNA Binding Ribonucleoprotein Complex Localization Male Meiotic Nuclear Division U4atac SnRNP	Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Keratin Filament Regulation Of RNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Intermediate Filament Regulation Of Gene Expression Structural Constituent Of Skin Epidermis Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process DNA Binding Nucleus Regulation Of Metabolic Process Intermediate Filament Organization Metal Ion Binding Postsynaptic Cytosol Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Protein Binding Sequence-specific Double-stranded DNA Binding Titin Binding
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