ZSCAN22 and ZNF449

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZSCAN22	ZNF449
Description		zinc finger and SCAN domain containing 22	zinc finger protein 449
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Spermatogonial Cell Division
Pathways
Drugs
Diseases
GWAS
Interacting Genes		29 interacting genes: BYSL CDR2L DVL3 KCTD19 NEXN PGBD1 PRPF31 SERTAD2 TLK1 ZGPAT ZKSCAN4 ZKSCAN7 ZNF174 ZNF24 ZNF263 ZNF397 ZNF444 ZNF446 ZNF449 ZNF483 ZNF496 ZSCAN1 ZSCAN16 ZSCAN18 ZSCAN21 ZSCAN23 ZSCAN25 ZSCAN32 ZSCAN9	6 interacting genes: APP MAGOHB MORF4L1 PIN1 SCAND1 ZSCAN22
Entrez ID		342945	203523
HPRD ID		01315	06543
Ensembl ID		ENSG00000182318	ENSG00000173275
Uniprot IDs		P10073	Q6P9G9
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Metal Ion Binding Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Sequence-specific DNA Binding Ribonucleoprotein Complex Localization Male Meiotic Nuclear Division U4atac SnRNP	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Regulation Of DNA-templated Transcription Amylin Binding Regulation Of Macromolecule Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Protein Peptidyl-prolyl Isomerization Phosphothreonine Residue Binding Cis-trans Isomerase Activity Exon-exon Junction Subcomplex Mago-y14 Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Protein Localization To Nucleus Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of RNA Metabolic Process Positive Regulation Of Amyloid Fibril Formation Regulation Of Metabolic Process Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Phosphoserine Residue Binding
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