ZSCAN22 and ZKSCAN4

Number of citations of the paper that reports this interaction (PubMedID 26871637)
43

Data Source:
BioGRID (two hybrid)

		ZSCAN22	ZKSCAN4
Description		zinc finger and SCAN domain containing 22	zinc finger with KRAB and SCAN domains 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS			Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Basal metabolic rate ( 31453325) Basal metabolic rate variance ( 31453325) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278) Schizophrenia ( 30285260) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		29 interacting genes: BYSL CDR2L DVL3 KCTD19 NEXN PGBD1 PRPF31 SERTAD2 TLK1 ZGPAT ZKSCAN4 ZKSCAN7 ZNF174 ZNF24 ZNF263 ZNF397 ZNF444 ZNF446 ZNF449 ZNF483 ZNF496 ZSCAN1 ZSCAN16 ZSCAN18 ZSCAN21 ZSCAN23 ZSCAN25 ZSCAN32 ZSCAN9	19 interacting genes: CABP5 IL36RN LXN MAP1LC3A MDM4 MEOX2 OGT OSGIN1 PSMA6 TIAM1 TRIM39 ZKSCAN7 ZNF397 ZNF483 ZNF496 ZSCAN20 ZSCAN22 ZSCAN30 ZSCAN32
Entrez ID		342945	387032
HPRD ID		01315	15768
Ensembl ID		ENSG00000182318	ENSG00000187626
Uniprot IDs		P10073	A0A0S2Z658 B7Z7H3 Q969J2
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Metal Ion Binding Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Sequence-specific DNA Binding Ribonucleoprotein Complex Localization Male Meiotic Nuclear Division U4atac SnRNP	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Zinc Ion Binding Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Protein Catabolic Process Metal Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Purine Ribonucleoside Triphosphate Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Primary Metabolic Process Mitophagy Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process
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