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HIST2H3A and ING1
Number of citations of the paper that reports this interaction (PMID
12015309
)
24
Data Source:
BioGRID
(enzymatic study)
HIST2H3A
ING1
Gene Name
histone cluster 2, H3a
inhibitor of growth family, member 1
Image
Gene Ontology Annotations
Cellular Component
Nucleosome
Extracellular Region
Nucleus
Nucleoplasm
Extracellular Vesicular Exosome
Nucleus
Molecular Function
DNA Binding
Protein Binding
Protein Heterodimerization Activity
Protein Binding
Zinc Ion Binding
Methylated Histone Binding
Biological Process
Chromatin Silencing At RDNA
Blood Coagulation
Gene Expression
DNA Methylation On Cytosine
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Protein Import Into Nucleus
Cell Cycle
Negative Regulation Of Cell Proliferation
Regulation Of Cell Death
Chromatin Modification
Negative Regulation Of Cell Growth
Positive Regulation Of Transcription, DNA-templated
Pathways
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Mitotic Prophase
PKMTs methylate histone lysines
Regulatory RNA pathways
RNA Polymerase I Promoter Clearance
HDMs demethylate histones
Cellular Senescence
Signaling by Wnt
HATs acetylate histones
M Phase
Amyloids
NoRC negatively regulates rRNA expression
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
DNA methylation
Transcriptional regulation by small RNAs
Meiotic recombination
HDACs deacetylate histones
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
RNA Polymerase I Transcription
formation of the beta-catenin:TCF transactivating complex
Epigenetic regulation of gene expression
Senescence-Associated Secretory Phenotype (SASP)
Negative epigenetic regulation of rRNA expression
Factors involved in megakaryocyte development and platelet production
PRC2 methylates histones and DNA
Cell Cycle, Mitotic
RMTs methylate histone arginines
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
TCF dependent signaling in response to WNT
RNA Polymerase I Promoter Opening
SIRT1 negatively regulates rRNA Expression
Signaling by WNT in cancer
Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Protein-Protein Interactions
16 interactors:
CBX5
DNTTIP2
EHMT2
GTF3C4
HDAC9
ING1
KDM5A
KDM5C
LALBA
MECP2
PADI4
PRDM1
PRMT6
SETDB1
SUV39H1
UHRF1
29 interactors:
BRMS1
BRMS1L
COPS2
DMAP1
EP300
ESR1
HDAC1
HDAC2
HIST2H3A
HIST2H3C
HIST4H4
KAT2B
LINC00152
MRGBP
NQO1
PCNA
RBBP4
RBBP7
RBP1
SAP30
SFN
SIN3A
TP53
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
Entrez ID
333932
3621
HPRD ID
03337
Ensembl ID
ENSG00000153487
Uniprot IDs
Q71DI3
Q9UK53
PDB IDs
2IIJ
2X4W
2X4X
2X4Y
3AV1
3DB3
3MO8
3QO2
3R93
2QIC
Enriched GO Terms of Interacting Partners
?
Chromatin Modification
Chromatin Organization
Histone Modification
Chromosome Organization
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Methylation
Regulation Of RNA Metabolic Process
Histone H3-K9 Modification
Negative Regulation Of Cellular Metabolic Process
Peptidyl-lysine Modification
Histone Methylation
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Organelle Organization
RNA Metabolic Process
Peptidyl-amino Acid Modification
Protein Methylation
Gene Expression
Cellular Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Macromolecule Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Histone H3-K9 Methylation
Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Protein Modification Process
Regulation Of Gene Expression, Epigenetic
Histone H3-K9 Trimethylation
Histone Lysine Methylation
Peptidyl-lysine Dimethylation
DNA Methylation On Cytosine
Peptidyl-lysine Methylation
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Protein Metabolic Process
Peptidyl-lysine Trimethylation
Chromatin Silencing
Regulation Of Cellular Process
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Negative Regulation Of Gene Expression
Chromatin Organization
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Negative Regulation Of Cellular Metabolic Process
Chromosome Organization
Negative Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression, Epigenetic
Chromatin Modification
Positive Regulation Of Mitochondrion Organization
Negative Regulation Of Biosynthetic Process
Regulation Of Mitochondrion Organization
Organelle Organization
Regulation Of Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Intrinsic Apoptotic Signaling Pathway
Regulation Of Metabolic Process
Regulation Of RNA Metabolic Process
Gene Expression
Regulation Of Gene Expression
Positive Regulation Of Intracellular Transport
Histone Modification
Chromatin Remodeling
Positive Regulation Of Apoptotic Signaling Pathway
Cellular Nitrogen Compound Metabolic Process
Apoptotic Signaling Pathway
Regulation Of Apoptotic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Regulation Of Cell Death
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
RNA Metabolic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Positive Regulation Of Cell Death
Regulation Of Intracellular Transport
Regulation Of Cellular Process
Histone Deacetylation
Protein Deacetylation
Tagcloud
?
13q33
bptf
col4a1
col4a2
d13s1315
d13s158
d13s278
d13s285
d13s779
d13s796
e2f
ets
flanking
genomatix
heterozygosity
hif1
loh
matinspector
microdeletion
nrsf
rel
softwares
sox
sox1
tfsearch
tsg
tsgs
warrants
Tagcloud (Difference)
?
13q33
bptf
col4a1
col4a2
d13s1315
d13s158
d13s278
d13s285
d13s779
d13s796
e2f
ets
flanking
genomatix
heterozygosity
hif1
loh
matinspector
microdeletion
nrsf
rel
softwares
sox
sox1
tfsearch
tsg
tsgs
warrants
Tagcloud (Intersection)
?