ING1 and RBBP7

Number of citations of the paper that reports this interaction (PMID 15451426)
21

Data Source:
HPRD (in vivo)

		ING1	RBBP7
Gene Name		inhibitor of growth family, member 1	retinoblastoma binding protein 7
Image
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm NuRD Complex ESC/E(Z) Complex
	Molecular Function	Protein Binding Zinc Ion Binding Methylated Histone Binding	RNA Binding Protein Binding
	Biological Process	Protein Import Into Nucleus Cell Cycle Negative Regulation Of Cell Proliferation Regulation Of Cell Death Chromatin Modification Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Replication Chromatin Organization Nucleosome Assembly Transcription, DNA-templated Multicellular Organismal Development Cell Proliferation Gene Expression Negative Regulation Of Cell Growth CENP-A Containing Nucleosome Assembly Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Cellular Heat Acclimation
Pathways			Chromosome Maintenance HDACs deacetylate histones Chromatin organization RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Promoter Clearance Deposition of new CENPA-containing nucleosomes at the centromere Epigenetic regulation of gene expression Cellular Senescence HATs acetylate histones PRC2 methylates histones and DNA RMTs methylate histone arginines Chromatin modifying enzymes Nucleosome assembly Oxidative Stress Induced Senescence
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: BRMS1 BRMS1L COPS2 DMAP1 EP300 ESR1 HDAC1 HDAC2 HIST2H3A HIST2H3C HIST4H4 KAT2B LINC00152 MRGBP NQO1 PCNA RBBP4 RBBP7 RBP1 SAP30 SFN SIN3A TP53 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	28 interactors: APPL1 APPL2 BCL11B BRCA1 BRMS1 BRMS1L CHD4 CREBBP DHX30 ESR1 GATAD2B HDAC1 HDAC2 HIST3H3 ING1 LINC00152 MBD3 MBD3L2 MTA2 NR2E3 RB1 RBBP4 RBP1 SALL2 SAP30 SIN3A SUV39H1 TWIST1
Entrez ID		3621	5931
HPRD ID		03337	04231
Ensembl ID		ENSG00000153487	ENSG00000102054
Uniprot IDs		Q9UK53	E9PC52 Q16576 Q6FHQ0
PDB IDs		2QIC	3CFS 3CFV
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Gene Expression Chromatin Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Cellular Metabolic Process Chromosome Organization Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Chromatin Modification Positive Regulation Of Mitochondrion Organization Negative Regulation Of Biosynthetic Process Regulation Of Mitochondrion Organization Organelle Organization Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Gene Expression Positive Regulation Of Intracellular Transport Histone Modification Chromatin Remodeling Positive Regulation Of Apoptotic Signaling Pathway Cellular Nitrogen Compound Metabolic Process Apoptotic Signaling Pathway Regulation Of Apoptotic Process Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Regulation Of Cell Death Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Nitrogen Compound Metabolic Process RNA Biosynthetic Process Positive Regulation Of Cell Death Regulation Of Intracellular Transport Regulation Of Cellular Process Histone Deacetylation Protein Deacetylation	Chromatin Organization Chromatin Modification Chromosome Organization Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression, Epigenetic Transcription, DNA-templated Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Chromatin Remodeling Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process ATP-dependent Chromatin Remodeling Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Cellular Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Histone Modification Regulation Of Gene Expression Organelle Organization Macromolecule Biosynthetic Process Histone Deacetylation Protein Deacetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Rhythmic Process Histone H3-K9 Modification Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Eyelid Development In Camera-type Eye Tissue Development Negative Regulation Of Histone Acetylation
Tagcloud ?		13q33 bptf col4a1 col4a2 d13s1315 d13s158 d13s278 d13s285 d13s779 d13s796 e2f ets flanking genomatix heterozygosity hif1 loh matinspector microdeletion nrsf rel softwares sox sox1 tfsearch tsg tsgs warrants	accessibility acetyltransferase alanine applicable bait code govern h3s10 hat1 mimic nonhydrolyzable outlined partners phosphonomethylen pma posttranslational ptms pull recruit retinoblastoma s10 scheme silac studying tail tails threonine uncovered unmodified
Tagcloud (Difference) ?		13q33 bptf col4a1 col4a2 d13s1315 d13s158 d13s278 d13s285 d13s779 d13s796 e2f ets flanking genomatix heterozygosity hif1 loh matinspector microdeletion nrsf rel softwares sox sox1 tfsearch tsg tsgs warrants	accessibility acetyltransferase alanine applicable bait code govern h3s10 hat1 mimic nonhydrolyzable outlined partners phosphonomethylen pma posttranslational ptms pull recruit retinoblastoma s10 scheme silac studying tail tails threonine uncovered unmodified
Tagcloud (Intersection) ?