ING1 and BRMS1L

Number of citations of the paper that reports this interaction (PubMedID 15451426)
0

Data Source:
HPRD (in vivo)

		ING1	BRMS1L
Description		inhibitor of growth family member 1	BRMS1 like transcriptional repressor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Sin3-type Complex	Nucleus Nucleoplasm Sin3-type Complex
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding Histone H3K4me3 Reader Activity	Protein Binding Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Protein Import Into Nucleus Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Programmed Cell Death Positive Regulation Of DNA-templated Transcription Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Erosive tooth wear (severe vs non-severe) ( 29898447)
Interacting Genes		29 interacting genes: BRMS1 BRMS1L COPS2 CYTOR DMAP1 EP300 ESR1 EXOC4 H3C14 HDAC1 HDAC2 KAT2B MRGBP NQO1 PCNA RBBP4 RBBP7 RBP1 SAP30 SFN SIN3A TP53 UBC YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	22 interacting genes: ACTN2 AMOTL2 BRMS1 CEP70 CYTOR DEUP1 EXOC5 HDAC1 HDAC2 ING1 MCRS1 MID2 PBX1 PBX2 RBBP4 RBBP7 RBP1 SAP30 SIN3A TEX11 TULP3 TXLNA
Entrez ID		3621	84312
HPRD ID		03337	16564
Ensembl ID		ENSG00000153487	ENSG00000100916
Uniprot IDs		A0A0C4DFW2 Q9UK53	Q5PSV4
PDB IDs		2QIC
Enriched GO Terms of Interacting Partners?		Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Stem Cell Population Maintenance Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Stem Cell Population Maintenance Negative Regulation Of Biosynthetic Process Histone Deacetylase Binding Negative Regulation Of Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Transcription By RNA Polymerase II Histone Deacetylase Complex Phosphoserine Residue Binding Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of RNA Metabolic Process Chromatin Organization Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Chromatin Remodeling Nucleus Rhythmic Process Regulation Of Gene Expression Protein Sequestering Activity NuRD Complex Regulation Of Cell Fate Commitment Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Signal Transduction Regulation Of Metabolic Process Protein-containing Complex Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Cell Migration Cellular Response To Stress Chromatin Binding Regulation Of Cell Fate Specification Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Nucleoplasm Enzyme Binding	Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone Deacetylase Complex Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway NuRD Complex Negative Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Regulation Of Cell Fate Specification Negative Regulation Of Developmental Process Regulation Of Cell Fate Commitment Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process ESC/E(Z) Complex Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Stem Cell Differentiation Regulation Of Locomotion Regulation Of Nucleobase-containing Compound Metabolic Process Protein Lysine Delactylase Activity Fungiform Papilla Formation Negative Regulation Of Nucleobase-containing Compound Metabolic Process NF-kappaB Binding Protein Decrotonylase Activity Histone Decrotonylase Activity Brain Development Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Hair Follicle Placode Formation Negative Regulation Of DNA-templated Transcription Nucleosomal DNA Binding Negative Regulation Of RNA Biosynthetic Process Histone Deacetylase Binding Positive Regulation Of RNA Metabolic Process Negative Regulation Of Signal Transduction Negative Regulation Of RNA Metabolic Process Cellular Response To Dopamine NURF Complex Response To Dopamine Embryonic Digit Morphogenesis Negative Regulation Of Cell Communication
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