ING1

Description		inhibitor of growth family member 1
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GO Annotations	Cellular Component	Nucleus Sin3-type Complex
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding Histone H3K4me3 Reader Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Protein Import Into Nucleus Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Programmed Cell Death Positive Regulation Of DNA-templated Transcription Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Erosive tooth wear (severe vs non-severe) ( 29898447)
Interacting Genes		29 interacting genes: BRMS1 BRMS1L COPS2 CYTOR DMAP1 EP300 ESR1 EXOC4 H3C14 HDAC1 HDAC2 KAT2B MRGBP NQO1 PCNA RBBP4 RBBP7 RBP1 SAP30 SFN SIN3A TP53 UBC YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Entrez ID		3621
HPRD ID		03337
Ensembl ID		ENSG00000153487
Uniprot IDs		A0A0C4DFW2 Q9UK53
PDB IDs		2QIC
Enriched GO Terms of Interacting Partners?		Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Stem Cell Population Maintenance Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Stem Cell Population Maintenance Negative Regulation Of Biosynthetic Process Histone Deacetylase Binding Negative Regulation Of Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Transcription By RNA Polymerase II Histone Deacetylase Complex Phosphoserine Residue Binding Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of RNA Metabolic Process Chromatin Organization Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Chromatin Remodeling Nucleus Rhythmic Process Regulation Of Gene Expression Protein Sequestering Activity NuRD Complex Regulation Of Cell Fate Commitment Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Signal Transduction Regulation Of Metabolic Process Protein-containing Complex Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Cell Migration Cellular Response To Stress Chromatin Binding Regulation Of Cell Fate Specification Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Nucleoplasm Enzyme Binding
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