RBPMS and NEU4

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		RBPMS	NEU4
Gene Name		RNA binding protein with multiple splicing	sialidase 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Mitochondrion Lysosome Organelle Inner Membrane Lysosomal Lumen
	Molecular Function	Nucleotide Binding Transcription Coactivator Activity Protein Binding Poly(A) Binding Poly(A) RNA Binding	Exo-alpha-sialidase Activity Protein Binding Exo-alpha-(2->3)-sialidase Activity Exo-alpha-(2->6)-sialidase Activity Exo-alpha-(2->8)-sialidase Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of SMAD Protein Import Into Nucleus	Dolichol-linked Oligosaccharide Biosynthetic Process Glycoprotein Catabolic Process Sphingolipid Metabolic Process Glycosphingolipid Metabolic Process Ganglioside Catabolic Process Oligosaccharide Catabolic Process Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process Small Molecule Metabolic Process
Pathways			Diseases of glycosylation Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MOGS causes MOGS-CDG (CDG-2b) Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Post-translational protein modification Defective ALG3 causes ALG3-CDG (CDG-1d) Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Synthesis of substrates in N-glycan biosythesis Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Sialic acid metabolism Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins
Drugs
Diseases
GWAS		Heart rate variability traits ( 22174390)
Protein-Protein Interactions		174 interactors: ADAM15 AES AMMECR1 APLN ARHGAP9 ARHGEF39 ARID5A ATN1 ATP6V0E2 ATXN1 BANP BBS2 BCL6B BHLHE40 BOLL C11orf87 C1orf111 C1orf94 C20orf195 C22orf39 C9orf24 CAMK2B CCER1 CCNG1 CCNK CDC23 CDC42EP1 CNNM3 CRBN CREB5 CRYBA1 CSN3 CSNK1G2-AS1 CYBA DAZAP2 DCAF8 DCDC2B DCTN5 DMRT3 DOK3 DOK6 DPYSL4 DTX2 DVL2 EFEMP2 ENKD1 EWSR1 EYA2 FAM103A1 FAM124B FAM168A FASTK FBF1 FBXL18 FOXC2 FOXP3 FOXS1 FXR2 GCM2 GLYCTK GPATCH2L GPS2 GRAP GRAP2 GSE1 HEY2 HEYL HNRNPLL HOXA1 HOXA9 HOXB9 IGF2 ILF3 INCA1 INIP IP6K2 KCTD9 KIF1A KIR2DL4 KPNA2 KRAS KRTAP12-2 KRTAP19-5 KRTAP19-7 KRTAP23-1 KRTAP8-1 LGALS9C LINC00482 LINC00588 LINC00908 LINC01547 LINC01588 LMO4 LOC142937 LOC148413 LONRF1 LRRC41 LRRC75A-AS1 LZTS2 MAGED1 MCM5 MGAT5B MVP MYOZ2 NAB2 NAPRT NEDD9 NEU4 NR1D2 NYNRIN OTX1 PAPD4 PDLIM4 PER1 PGLS PHF1 PIH1D1 PIN1 PITX1 PLAC8 POGZ POM121 PRKAA1 PRKAA2 PRKAB2 PRR20A QKI R3HDM2 RABL6 RBFOX1 RBFOX2 RDH12 RHOBTB3 RHOXF2 RIPPLY1 ROR2 RTP5 RUSC1 SBF2 SEMA4G SERF2 SF1 SH3RF2 SIRPB1 SMUG1 SNRPB SNRPC SPATA8 SPG7 STRBP TBX6 TEX37 TFG TIE1 TINAGL1 TMSB4X TOLLIP TOR1AIP2 TRIP13 TTLL10 TUSC2 VENTX VHL VHLL VPS37C WDR54 WDR90 WDYHV1 YPEL3 ZBTB32 ZC3H10 ZNF385C ZNF488 ZNF581	8 interactors: AP2B1 MDFI PLSCR1 PSMA3 RBPMS RHOXF2 TCF4 TRIP6
Entrez ID		11030	129807
HPRD ID		11870	12249
Ensembl ID		ENSG00000157110	ENSG00000204099
Uniprot IDs		B4E3T4 D3DSV0 Q93062	B3KR54 Q8WWR8
PDB IDs		1BNY
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process RNA Metabolic Process Transcription, DNA-templated Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Developmental Process Regulation Of Cellular Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Anatomical Structure Development Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Response To Stimulus Cellular Response To Stimulus Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Signaling Signal Transduction Cellular Metabolic Process Cell Communication Positive Regulation Of Macromolecule Biosynthetic Process System Development Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Anterior/posterior Pattern Specification Biosynthetic Process Regulation Of Circadian Rhythm Organ Development Insulin Receptor Signaling Pathway Cellular Process Response To Radiation	Regulation Of Nucleocytoplasmic Transport Regulation Of Intracellular Protein Transport Regulation Of Signal Transduction Regulation Of Signaling Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Intracellular Transport Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Positive Regulation Of Signal Transduction Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Localization To Nucleus Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Transport Regulation Of Protein Localization Regulation Of Wnt Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Protein Transport Regulation Of Cellular Localization Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Cellular Metabolic Process Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Negative Regulation Of Canonical Wnt Signaling Pathway Maintenance Of DNA Repeat Elements Regulation Of Gene Expression Positive Regulation Of Transport Release Of Cytoplasmic Sequestered NF-kappaB Regulation Of Metabolic Process Phosphatidylserine Biosynthetic Process Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Embryonic Hindgut Morphogenesis Positive Regulation Of Intracellular Signal Transduction Embryonic Genitalia Morphogenesis Positive Regulation Of Metabolic Process Regulation Of Canonical Wnt Signaling Pathway Gene Expression Myoblast Fate Commitment Antigen Processing And Presentation Of Peptide Antigen
Tagcloud ?			1140f01 9i acetylneuraminic alliance antipsychotic bim dana deoxy didehydro galardin gm6001 gpcr htc htcs irbeta irs1 neu1 neu3 neuraminidase neuromedin olanzapine oseltamivir overly piperazine sialidase sialidosis tamiflu uncover wg544
Tagcloud (Difference) ?			1140f01 9i acetylneuraminic alliance antipsychotic bim dana deoxy didehydro galardin gm6001 gpcr htc htcs irbeta irs1 neu1 neu3 neuraminidase neuromedin olanzapine oseltamivir overly piperazine sialidase sialidosis tamiflu uncover wg544
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