RBPMS and CRBN

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RBPMS	CRBN
Gene Name		RNA binding protein with multiple splicing	cereblon
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleus Nucleolus Cytoplasm Membrane Cul4A-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Nucleotide Binding Transcription Coactivator Activity Protein Binding Poly(A) Binding Poly(A) RNA Binding	ATP-dependent Peptidase Activity Protein Binding Metal Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of SMAD Protein Import Into Nucleus	Protein Ubiquitination Negative Regulation Of Protein Homooligomerization Negative Regulation Of Ion Transmembrane Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Homodimerization Activity
Pathways
Drugs
Diseases
GWAS		Heart rate variability traits ( 22174390)	Immune response to smallpox vaccine (IL-6) ( 22542470) White matter integrity ( 23218918)
Protein-Protein Interactions		174 interactors: ADAM15 AES AMMECR1 APLN ARHGAP9 ARHGEF39 ARID5A ATN1 ATP6V0E2 ATXN1 BANP BBS2 BCL6B BHLHE40 BOLL C11orf87 C1orf111 C1orf94 C20orf195 C22orf39 C9orf24 CAMK2B CCER1 CCNG1 CCNK CDC23 CDC42EP1 CNNM3 CRBN CREB5 CRYBA1 CSN3 CSNK1G2-AS1 CYBA DAZAP2 DCAF8 DCDC2B DCTN5 DMRT3 DOK3 DOK6 DPYSL4 DTX2 DVL2 EFEMP2 ENKD1 EWSR1 EYA2 FAM103A1 FAM124B FAM168A FASTK FBF1 FBXL18 FOXC2 FOXP3 FOXS1 FXR2 GCM2 GLYCTK GPATCH2L GPS2 GRAP GRAP2 GSE1 HEY2 HEYL HNRNPLL HOXA1 HOXA9 HOXB9 IGF2 ILF3 INCA1 INIP IP6K2 KCTD9 KIF1A KIR2DL4 KPNA2 KRAS KRTAP12-2 KRTAP19-5 KRTAP19-7 KRTAP23-1 KRTAP8-1 LGALS9C LINC00482 LINC00588 LINC00908 LINC01547 LINC01588 LMO4 LOC142937 LOC148413 LONRF1 LRRC41 LRRC75A-AS1 LZTS2 MAGED1 MCM5 MGAT5B MVP MYOZ2 NAB2 NAPRT NEDD9 NEU4 NR1D2 NYNRIN OTX1 PAPD4 PDLIM4 PER1 PGLS PHF1 PIH1D1 PIN1 PITX1 PLAC8 POGZ POM121 PRKAA1 PRKAA2 PRKAB2 PRR20A QKI R3HDM2 RABL6 RBFOX1 RBFOX2 RDH12 RHOBTB3 RHOXF2 RIPPLY1 ROR2 RTP5 RUSC1 SBF2 SEMA4G SERF2 SF1 SH3RF2 SIRPB1 SMUG1 SNRPB SNRPC SPATA8 SPG7 STRBP TBX6 TEX37 TFG TIE1 TINAGL1 TMSB4X TOLLIP TOR1AIP2 TRIP13 TTLL10 TUSC2 VENTX VHL VHLL VPS37C WDR54 WDR90 WDYHV1 YPEL3 ZBTB32 ZC3H10 ZNF385C ZNF488 ZNF581	5 interactors: KDM1A MEIS2 PAK7 RBPMS SUV39H1
Entrez ID		11030	51185
HPRD ID		11870	16750
Ensembl ID		ENSG00000157110	ENSG00000113851
Uniprot IDs		B4E3T4 D3DSV0 Q93062	Q96SW2
PDB IDs		1BNY
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process RNA Metabolic Process Transcription, DNA-templated Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Developmental Process Regulation Of Cellular Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Anatomical Structure Development Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Response To Stimulus Cellular Response To Stimulus Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Signaling Signal Transduction Cellular Metabolic Process Cell Communication Positive Regulation Of Macromolecule Biosynthetic Process System Development Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Anterior/posterior Pattern Specification Biosynthetic Process Regulation Of Circadian Rhythm Organ Development Insulin Receptor Signaling Pathway Cellular Process Response To Radiation	Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Myeloid Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Apoptotic Signaling Pathway Histone H3-K9 Dimethylation RNA Metabolic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Gene Expression Positive Regulation Of Megakaryocyte Differentiation Histone H3-K9 Trimethylation Cellular Macromolecule Biosynthetic Process Positive Regulation Of Hormone Biosynthetic Process Peptidyl-lysine Dimethylation Macromolecule Biosynthetic Process Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Histone Modification Positive Regulation Of SMAD Protein Import Into Nucleus Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Chromatin Silencing At RDNA Granulocyte Differentiation Regulation Of SMAD Protein Import Into Nucleus Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Erythrocyte Differentiation Negative Regulation Of Circadian Rhythm Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Transcription, DNA-templated Histone H3-K9 Methylation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Histone H3-K4 Methylation Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of RNA Metabolic Process Regulation Of Hormone Biosynthetic Process Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Peptidyl-lysine Trimethylation Nucleobase-containing Compound Metabolic Process
Tagcloud ?			activates amp ampk binds cereblon controlling delayed deletion dephosphorylation desensitized eif2alpha embryonic endoplasmic fibroblast implying inducers lastly mechanistically perk pkr promoting propose reconstitution regulates reticulum reversed stimuli stress unfolded
Tagcloud (Difference) ?			activates amp ampk binds cereblon controlling delayed deletion dephosphorylation desensitized eif2alpha embryonic endoplasmic fibroblast implying inducers lastly mechanistically perk pkr promoting propose reconstitution regulates reticulum reversed stimuli stress unfolded
Tagcloud (Intersection) ?