RBPMS and IGF2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RBPMS	IGF2
Gene Name		RNA binding protein with multiple splicing	insulin-like growth factor 2
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Extracellular Region Extracellular Space Plasma Membrane Platelet Alpha Granule Lumen Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding Transcription Coactivator Activity Protein Binding Poly(A) Binding Poly(A) RNA Binding	Insulin Receptor Binding Insulin-like Growth Factor Receptor Binding Hormone Activity Protein Binding Growth Factor Activity Receptor Activator Activity Protein Serine/threonine Kinase Activator Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of SMAD Protein Import Into Nucleus	Skeletal System Development Osteoblast Differentiation Positive Regulation Of Protein Phosphorylation Platelet Degranulation Glucose Metabolic Process Regulation Of Gene Expression By Genetic Imprinting Regulation Of Transcription, DNA-templated Multicellular Organismal Development Female Pregnancy Blood Coagulation Memory Positive Regulation Of Cell Proliferation Insulin Receptor Signaling Pathway Response To Radiation Organ Morphogenesis Platelet Activation Exocrine Pancreas Development Response To Nutrient Levels Response To Estradiol Response To Nicotine Insulin Receptor Signaling Pathway Via Phosphatidylinositol 3-kinase Positive Regulation Of Activated T Cell Proliferation Response To Drug Positive Regulation Of Catalytic Activity Positive Regulation Of MAPK Cascade Cellular Protein Metabolic Process Response To Ethanol Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Peptidyl-tyrosine Phosphorylation Striated Muscle Cell Differentiation Positive Regulation Of Protein Kinase B Signaling Cellular Response To Mechanical Stimulus Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Steroid Hormone Biosynthetic Process Positive Regulation Of Receptor Activity Positive Regulation Of Glycogen (starch) Synthase Activity
Pathways			IRS-related events triggered by IGF1R Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Response to elevated platelet cytosolic Ca2+ Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) SHC-related events triggered by IGF1R Platelet degranulation Platelet activation, signaling and aggregation IGF1R signaling cascade
Drugs
Diseases
GWAS		Heart rate variability traits ( 22174390)	DNA methylation (variation) ( 23725790) Femoral neck bone geometry and menarche (age at onset) ( 23593202) Prostate cancer ( 19767753)
Protein-Protein Interactions		174 interactors: ADAM15 AES AMMECR1 APLN ARHGAP9 ARHGEF39 ARID5A ATN1 ATP6V0E2 ATXN1 BANP BBS2 BCL6B BHLHE40 BOLL C11orf87 C1orf111 C1orf94 C20orf195 C22orf39 C9orf24 CAMK2B CCER1 CCNG1 CCNK CDC23 CDC42EP1 CNNM3 CRBN CREB5 CRYBA1 CSN3 CSNK1G2-AS1 CYBA DAZAP2 DCAF8 DCDC2B DCTN5 DMRT3 DOK3 DOK6 DPYSL4 DTX2 DVL2 EFEMP2 ENKD1 EWSR1 EYA2 FAM103A1 FAM124B FAM168A FASTK FBF1 FBXL18 FOXC2 FOXP3 FOXS1 FXR2 GCM2 GLYCTK GPATCH2L GPS2 GRAP GRAP2 GSE1 HEY2 HEYL HNRNPLL HOXA1 HOXA9 HOXB9 IGF2 ILF3 INCA1 INIP IP6K2 KCTD9 KIF1A KIR2DL4 KPNA2 KRAS KRTAP12-2 KRTAP19-5 KRTAP19-7 KRTAP23-1 KRTAP8-1 LGALS9C LINC00482 LINC00588 LINC00908 LINC01547 LINC01588 LMO4 LOC142937 LOC148413 LONRF1 LRRC41 LRRC75A-AS1 LZTS2 MAGED1 MCM5 MGAT5B MVP MYOZ2 NAB2 NAPRT NEDD9 NEU4 NR1D2 NYNRIN OTX1 PAPD4 PDLIM4 PER1 PGLS PHF1 PIH1D1 PIN1 PITX1 PLAC8 POGZ POM121 PRKAA1 PRKAA2 PRKAB2 PRR20A QKI R3HDM2 RABL6 RBFOX1 RBFOX2 RDH12 RHOBTB3 RHOXF2 RIPPLY1 ROR2 RTP5 RUSC1 SBF2 SEMA4G SERF2 SF1 SH3RF2 SIRPB1 SMUG1 SNRPB SNRPC SPATA8 SPG7 STRBP TBX6 TEX37 TFG TIE1 TINAGL1 TMSB4X TOLLIP TOR1AIP2 TRIP13 TTLL10 TUSC2 VENTX VHL VHLL VPS37C WDR54 WDR90 WDYHV1 YPEL3 ZBTB32 ZC3H10 ZNF385C ZNF488 ZNF581	22 interactors: BAG6 FAF1 GPC3 IDE IGF1R IGF2R IGFBP1 IGFBP2 IGFBP3 IGFBP4 IGFBP5 IGFBP6 IGFBP7 INSR NMRK2 NOV PCSK4 PLG RBPMS TF VTN WISP2
Entrez ID		11030	3481
HPRD ID		11870	00939
Ensembl ID		ENSG00000157110	ENSG00000167244
Uniprot IDs		B4E3T4 D3DSV0 Q93062	P01344
PDB IDs		1BNY	1GF2 1IGL 2L29 2V5P 3E4Z 3KR3
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process RNA Metabolic Process Transcription, DNA-templated Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Developmental Process Regulation Of Cellular Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Anatomical Structure Development Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Response To Stimulus Cellular Response To Stimulus Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Signaling Signal Transduction Cellular Metabolic Process Cell Communication Positive Regulation Of Macromolecule Biosynthetic Process System Development Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Anterior/posterior Pattern Specification Biosynthetic Process Regulation Of Circadian Rhythm Organ Development Insulin Receptor Signaling Pathway Cellular Process Response To Radiation	Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Growth Regulation Of Cellular Component Organization Regulation Of Cell Growth Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Type B Pancreatic Cell Proliferation Regulation Of Cell Proliferation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Developmental Process Regulation Of Signal Transduction Regulation Of Glucose Metabolic Process Regulation Of Signaling Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Insulin Receptor Signaling Pathway Cellular Response To Hormone Stimulus Regulation Of Carbohydrate Metabolic Process Regulation Of Cell Migration Regulation Of Phosphorylation Reproductive Process Regulation Of Cell Motility Exocrine Pancreas Development Exocrine System Development Cellular Protein Metabolic Process Negative Regulation Of Cell Proliferation Regulation Of Locomotion Regulation Of Cellular Component Movement Regulation Of Phosphorus Metabolic Process Regulation Of Protein Phosphorylation Cellular Response To Insulin Stimulus Response To Stimulus Positive Regulation Of Protein Kinase B Signaling Cellular Response To Organonitrogen Compound Regulation Of Cellular Process Male Sex Determination Anatomical Structure Development Tissue Development Negative Regulation Of Smooth Muscle Cell Migration Protein Tetramerization Response To Insulin Response To Hormone Insulin-like Growth Factor Receptor Signaling Pathway Signal Transduction Cellular Response To Peptide Hormone Stimulus Regulation Of Protein Kinase B Signaling
Tagcloud ?			affects biological blast carrying cdna cecum crossed deleted disrupted excess exclusively igf2r involve mannose must organ organs overexpressing paternal phenotypes proteolytic sdeltaigf2r sigf2r slow solely soluble stomach transgenics transmembrane
Tagcloud (Difference) ?			affects biological blast carrying cdna cecum crossed deleted disrupted excess exclusively igf2r involve mannose must organ organs overexpressing paternal phenotypes proteolytic sdeltaigf2r sigf2r slow solely soluble stomach transgenics transmembrane
Tagcloud (Intersection) ?