HNRNPAB and PTBP1

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		HNRNPAB	PTBP1
Gene Name		heterogeneous nuclear ribonucleoprotein A/B	polypyrimidine tract binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Ribonucleoprotein Complex RNA Polymerase II Transcription Factor Complex	Nucleoplasm Nucleolus Membrane Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Binding MRNA Binding Sequence-specific DNA Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding Protein Binding Poly-pyrimidine Tract Binding Pre-mRNA Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Epithelial To Mesenchymal Transition Positive Regulation Of Transcription, DNA-templated	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Negative Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Muscle Cell Differentiation
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: ACTB DEDD2 ELAVL2 ERG HIST3H3 HMGA1 HOXC13 HOXD4 IL7R POLR3D PTBP1 PTBP2 RBFOX2 TP63 USP19 YWHAG	27 interactors: APBB1 APP CALCOCO2 CASP3 ELAVL1 FUS HIST3H3 HMGA1 HMGA2 HNRNPAB HNRNPK HNRNPL IL7R NONO PCBP1 PCBP2 PCBP3 PRKACA QKI RAVER1 RAVER2 RBFOX2 RBM10 SFPQ SNRPA SRPK2 ZMYM2
Entrez ID		3182	5725
HPRD ID		04067	02823
Ensembl ID		ENSG00000197451	ENSG00000011304
Uniprot IDs		Q99729	P26599
PDB IDs		3S7R	1QM9 1SJQ 1SJR 2AD9 2ADB 2ADC 2EVZ 3ZZY 3ZZZ
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of RNA Splicing Regulation Of Cellular Senescence Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Regulation Of Alternative MRNA Splicing, Via Spliceosome Homeostatic Process Negative Regulation Of Cellular Metabolic Process Chromatin Remodeling Positive Regulation Of Apoptotic Signaling Pathway Transcription, DNA-templated RNA Processing RNA Biosynthetic Process Epidermal Cell Division Ectoderm And Mesoderm Interaction Negative Regulation Of Potassium Ion Export Regulation Of MRNA Splicing, Via Spliceosome Cell Aging Regulation Of Heart Rate By Hormone Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development Interleukin-7-mediated Signaling Pathway Oncogene-induced Cell Senescence RNA Splicing Apoptotic Signaling Pathway Regulation Of MRNA Processing Cellular Metabolic Process Hair Follicle Development Hair Cycle Process Regulation Of Epidermal Cell Division Senescence-associated Heterochromatin Focus Assembly Regulation Of Cellular Process Hair Cycle MRNA Processing Positive Regulation Of Cellular Senescence Female Genitalia Morphogenesis Regulation Of Cell Differentiation Radial Glia Guided Migration Of Purkinje Cell Regulation Of Cellular Response To Hypoxia Regulation Of Definitive Erythrocyte Differentiation Cloacal Septation	MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Oncogene-induced Cell Senescence Positive Regulation Of Gene Expression Senescence-associated Heterochromatin Focus Assembly Positive Regulation Of Cellular Senescence Cellular Metabolic Process Positive Regulation Of Cell Aging Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Heterochromatin Assembly Cell Morphogenesis DNA Metabolic Process Cell Morphogenesis Involved In Differentiation Anatomical Structure Morphogenesis Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Heterochromatin Organization DNA Catabolic Process, Endonucleolytic Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Cycle Regulation Of Cell Cycle Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Stress Regulation Of Cellular Senescence Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway DNA Repair Chromatin Modification Cell Development Regulation Of Stem Cell Maintenance Response To Light Stimulus Positive Regulation Of Cell Death DNA Catabolic Process Cellular Senescence Chromosome Organization Extracellular Matrix Organization
Tagcloud ?			aminobutyric ampa amphibians calmodulin camkiialpha clathrin demonstrations elongated exclude fiber gaba immunoblot intriguingly isoxazolepropionic lens lenses morphogenetic neurogenesis nonsense parallels polypyrimidine protrusions psd ptbp2 scaffold spacing spine splicing
Tagcloud (Difference) ?			aminobutyric ampa amphibians calmodulin camkiialpha clathrin demonstrations elongated exclude fiber gaba immunoblot intriguingly isoxazolepropionic lens lenses morphogenetic neurogenesis nonsense parallels polypyrimidine protrusions psd ptbp2 scaffold spacing spine splicing
Tagcloud (Intersection) ?