PTBP1 and RBM10

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		PTBP1	RBM10
Gene Name		polypyrimidine tract binding protein 1	RNA binding motif protein 10
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Membrane Extracellular Vesicular Exosome	Nucleus Nucleoplasm
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly-pyrimidine Tract Binding Pre-mRNA Binding Poly(A) RNA Binding	Nucleotide Binding Protein Binding Zinc Ion Binding Protein Complex Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Negative Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Muscle Cell Differentiation	MRNA Processing Biological_process RNA Splicing
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: APBB1 APP CALCOCO2 CASP3 ELAVL1 FUS HIST3H3 HMGA1 HMGA2 HNRNPAB HNRNPK HNRNPL IL7R NONO PCBP1 PCBP2 PCBP3 PRKACA QKI RAVER1 RAVER2 RBFOX2 RBM10 SFPQ SNRPA SRPK2 ZMYM2	21 interactors: AES ATN1 CCAR1 CSNK2A1 DDX5 FAM124A HNRNPH2 HNRNPK IK NHP2L1 PRCC PTBP1 PTBP2 RBM4 SF1 SF3A1 SREK1 SRSF6 TBC1D22B U2AF1 UBQLN4
Entrez ID		5725	8241
HPRD ID		02823	02095
Ensembl ID		ENSG00000011304	ENSG00000182872
Uniprot IDs		P26599	P98175 Q7Z3D7
PDB IDs		1QM9 1SJQ 1SJR 2AD9 2ADB 2ADC 2EVZ 3ZZY 3ZZZ	2LXI 2M2B
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Oncogene-induced Cell Senescence Positive Regulation Of Gene Expression Senescence-associated Heterochromatin Focus Assembly Positive Regulation Of Cellular Senescence Cellular Metabolic Process Positive Regulation Of Cell Aging Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Heterochromatin Assembly Cell Morphogenesis DNA Metabolic Process Cell Morphogenesis Involved In Differentiation Anatomical Structure Morphogenesis Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Heterochromatin Organization DNA Catabolic Process, Endonucleolytic Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Cycle Regulation Of Cell Cycle Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Stress Regulation Of Cellular Senescence Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway DNA Repair Chromatin Modification Cell Development Regulation Of Stem Cell Maintenance Response To Light Stimulus Positive Regulation Of Cell Death DNA Catabolic Process Cellular Senescence Chromosome Organization Extracellular Matrix Organization	RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing RNA Metabolic Process Gene Expression Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Splice Site Selection Nitrogen Compound Metabolic Process Spliceosomal Complex Assembly Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Regulation Of MRNA Processing Ribonucleoprotein Complex Biogenesis MRNA 3'-splice Site Recognition Ribonucleoprotein Complex Assembly Negative Regulation Of Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Rhythmic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Termination Of RNA Polymerase II Transcription Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process MRNA Export From Nucleus Cellular Macromolecular Complex Assembly DNA-templated Transcription, Termination Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Export From Nucleus Regulation Of Metabolic Process MRNA 3'-end Processing Biosynthetic Process Primary Sex Determination Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Anoikis RNA 3'-end Processing Negative Regulation Of Biosynthetic Process IRES-dependent Translational Initiation
Tagcloud ?		aminobutyric ampa amphibians calmodulin camkiialpha clathrin demonstrations elongated exclude fiber gaba immunoblot intriguingly isoxazolepropionic lens lenses morphogenetic neurogenesis nonsense parallels polypyrimidine protrusions psd ptbp2 scaffold spacing spine splicing	abcc12 braf dabrafenib deregulated deserve detoxification discover exploratory highlighted invasiveness klf17 melanoma mtefd1 nqo1 peaks responder responders rin1 seldi silico slain1 strongest surrogates tox3 tspo2 v600 vemurafenib z zbtb44
Tagcloud (Difference) ?		aminobutyric ampa amphibians calmodulin camkiialpha clathrin demonstrations elongated exclude fiber gaba immunoblot intriguingly isoxazolepropionic lens lenses morphogenetic neurogenesis nonsense parallels polypyrimidine protrusions psd ptbp2 scaffold spacing spine splicing	abcc12 braf dabrafenib deregulated deserve detoxification discover exploratory highlighted invasiveness klf17 melanoma mtefd1 nqo1 peaks responder responders rin1 seldi silico slain1 strongest surrogates tox3 tspo2 v600 vemurafenib z zbtb44
Tagcloud (Intersection) ?