PTBP1 and QKI

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PTBP1	QKI
Gene Name		polypyrimidine tract binding protein 1	QKI, KH domain containing, RNA binding
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Membrane Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly-pyrimidine Tract Binding Pre-mRNA Binding Poly(A) RNA Binding	MRNA Binding Protein Binding SH3 Domain Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Negative Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Muscle Cell Differentiation	Vasculogenesis MRNA Processing Regulation Of Translation Spermatid Development RNA Splicing Positive Regulation Of Gene Expression Myelination Muscle Cell Differentiation Long-chain Fatty Acid Biosynthetic Process MRNA Transport 3'-UTR-mediated MRNA Destabilization
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Response to TNF antagonist treatment ( 18615156)
Protein-Protein Interactions		27 interactors: APBB1 APP CALCOCO2 CASP3 ELAVL1 FUS HIST3H3 HMGA1 HMGA2 HNRNPAB HNRNPK HNRNPL IL7R NONO PCBP1 PCBP2 PCBP3 PRKACA QKI RAVER1 RAVER2 RBFOX2 RBM10 SFPQ SNRPA SRPK2 ZMYM2	34 interactors: APP ATXN1 C10orf10 CARM1 DAZ1 DAZ4 FUBP3 HCLS1 HNRNPH2 HNRNPK HNRNPLL IL7R NABP1 PCBP1 PCBP2 PCBP4 PRMT1 PSMF1 PTBP1 PTBP2 RALY RBFOX1 RBFOX2 RBM11 RBM14 RBM23 RBPMS RNF138 SERF2 SNRPA THAP1 U2AF2 USH1C WDR77
Entrez ID		5725	9444
HPRD ID		02823	06691
Ensembl ID		ENSG00000011304	ENSG00000112531
Uniprot IDs		P26599	Q8WY44 Q96PU8
PDB IDs		1QM9 1SJQ 1SJR 2AD9 2ADB 2ADC 2EVZ 3ZZY 3ZZZ	4JVH
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Oncogene-induced Cell Senescence Positive Regulation Of Gene Expression Senescence-associated Heterochromatin Focus Assembly Positive Regulation Of Cellular Senescence Cellular Metabolic Process Positive Regulation Of Cell Aging Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Heterochromatin Assembly Cell Morphogenesis DNA Metabolic Process Cell Morphogenesis Involved In Differentiation Anatomical Structure Morphogenesis Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Heterochromatin Organization DNA Catabolic Process, Endonucleolytic Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Cycle Regulation Of Cell Cycle Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Stress Regulation Of Cellular Senescence Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway DNA Repair Chromatin Modification Cell Development Regulation Of Stem Cell Maintenance Response To Light Stimulus Positive Regulation Of Cell Death DNA Catabolic Process Cellular Senescence Chromosome Organization Extracellular Matrix Organization See more	RNA Processing MRNA Processing MRNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Regulation Of RNA Splicing Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Intracellular Estrogen Receptor Signaling Pathway Regulation Of RNA Metabolic Process Negative Regulation Of RNA Splicing Neuromuscular Process Controlling Balance Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Cellular Metabolic Process Positive Regulation Of Gene Expression Neuromuscular Process Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Regulation Of Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Peptidyl-arginine N-methylation Intracellular Receptor Signaling Pathway Histone Arginine Methylation Negative Regulation Of MRNA Splicing, Via Spliceosome Peptidyl-arginine Methylation Positive Regulation Of Cellular Metabolic Process Cellular Process Positive Regulation Of Metabolic Process Positive Regulation Of RNA Splicing Histone H3-R17 Methylation Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Mitotic Cell Cycle Histone H3-R2 Methylation Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Parallel Actin Filament Bundle Assembly Interleukin-7-mediated Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Visual Learning Visual Behavior See more
Tagcloud ?		aminobutyric ampa amphibians calmodulin camkiialpha clathrin demonstrations elongated exclude fiber gaba immunoblot intriguingly isoxazolepropionic lens lenses morphogenetic neurogenesis nonsense parallels polypyrimidine protrusions psd ptbp2 scaffold spacing spine splicing	activate cal cancers clarify contribute currently cyclin d1 frequently malignancies mapk mitogen modulating newly occurring occurs oral oscc quaking regulative resulting shows squamous suppressor tumour uncontrolled underexpression unknown world
Tagcloud (Difference) ?		aminobutyric ampa amphibians calmodulin camkiialpha clathrin demonstrations elongated exclude fiber gaba immunoblot intriguingly isoxazolepropionic lens lenses morphogenetic neurogenesis nonsense parallels polypyrimidine protrusions psd ptbp2 scaffold spacing spine splicing	activate cal cancers clarify contribute currently cyclin d1 frequently malignancies mapk mitogen modulating newly occurring occurs oral oscc quaking regulative resulting shows squamous suppressor tumour uncontrolled underexpression unknown world
Tagcloud (Intersection) ?