PTBP1 and CCAT1

Number of citations of the paper that reports this interaction (PubMedID 37740243)
54

Data Source:
BioGRID (unspecified method, affinity chromatography technology, imaging technique)

		PTBP1	CCAT1
Description		polypyrimidine tract binding protein 1	colon cancer associated transcript 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Membrane Extracellular Exosome
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Poly-pyrimidine Tract Binding Pre-mRNA Binding	Promoter-enhancer Loop Anchoring Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Neurogenesis Negative Regulation Of RNA Splicing Regulation Of RNA Splicing Regulation Of Cell Differentiation Negative Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Muscle Cell Differentiation Positive Regulation Of Calcineurin-NFAT Signaling Cascade IRES-dependent Viral Translational Initiation Negative Regulation Of MRNA Metabolic Process	Chromatin Looping
Pathways		FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 34315874) Hematocrit ( 27863252 32888494) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Lymphocyte percentage of white cells ( 32888494) Red blood cell count ( 32888494) Refractive error ( 32231278) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Hip index ( 34021172) Multiple myeloma ( 27363682)
Interacting Genes		118 interacting genes: APBB1 APP CALCOCO2 CASP3 CCAT1 CEBPA FOXP1 FUS H3-4 HIF1A HMGA1 HMGA2 HNRNPAB HNRNPL HNRNPLL IL7R LIN28A LINC00624 LINC00839 LINC01554 MARK4 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NDUFV3 NONO OGT PCBP1 PCBP2 PCBP3 PKLR PRKACA PRPF40A QKI RAVER1 RAVER2 RBFOX2 RBM10 RNF10 SERPINB5 SFPQ SNCA SNRPA SRPK2 SUMO2 TRAK1 USP36 ZC3H8 ZMYM2	2 interacting genes: FABP5 PTBP1
Entrez ID		5725	100507056
HPRD ID		02823
Ensembl ID		ENSG00000011304
Uniprot IDs		A0A7I2V621 P26599
PDB IDs		1QM9 1SJQ 1SJR 2AD9 2ADB 2ADC 2EVZ 2N3O 3ZZY 3ZZZ 8BGF 8BWF
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process MRNA 3'-UTR Binding Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Extracellular Vesicle Negative Regulation Of Translation Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process MRNA Destabilization Positive Regulation Of MRNA Catabolic Process RNA Destabilization Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Cytokine Production Regulation Of Angiogenesis Regulation Of Vasculature Development Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration Regulation Of MRNA Stability Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Developmental Process Negative Regulation Of Cell Motility Regulation Of Translation Regulation Of RNA Stability Negative Regulation Of Locomotion Regulation Of MRNA Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Endothelial Cell Migration Negative Regulation Of Protein Metabolic Process Negative Regulation Of Signal Transduction Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Cytokine Production Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Cell Migration	Lipid Transport Across Blood-brain Barrier Retrograde Trans-synaptic Signaling By Endocannabinoid Regulation Of Retrograde Trans-synaptic Signaling By Endocanabinoid Poly-pyrimidine Tract Binding Long-chain Fatty Acid Transmembrane Transporter Activity Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Regulation Of Sensory Perception Of Pain Retinoic Acid Binding Negative Regulation Of D-glucose Transmembrane Transport Postsynaptic Density, Intracellular Component Regulation Of Prostaglandin Biosynthetic Process Phosphatidylcholine Biosynthetic Process Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Negative Regulation Of MRNA Splicing, Via Spliceosome IRES-dependent Viral Translational Initiation Pre-mRNA Binding Positive Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of RNA Splicing Fatty Acid Binding Postsynaptic Cytosol Positive Regulation Of Intracellular Signal Transduction Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Fatty Acid Biosynthetic Process Long-chain Fatty Acid Transport Positive Regulation Of Calcium-mediated Signaling Phosphatidylcholine Metabolic Process Positive Regulation Of Signal Transduction Negative Regulation Of Muscle Cell Differentiation Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Neuron Differentiation Regulation Of D-glucose Transmembrane Transport Transport Across Blood-brain Barrier Fatty Acid Transport Azurophil Granule Lumen Positive Regulation Of Cell Communication Positive Regulation Of Signaling Secretory Granule Membrane Regulation Of Fatty Acid Metabolic Process Regulation Of Calcium-mediated Signaling Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of MRNA Metabolic Process Regulation Of Intracellular Signal Transduction Negative Regulation Of Transmembrane Transport Neurogenesis Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Nervous System Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?