PTBP1 and RAVER1

Number of citations of the paper that reports this interaction (PMID 11724819)
35

Data Source:
HPRD (two hybrid, in vivo)

		PTBP1	RAVER1
Gene Name		polypyrimidine tract binding protein 1	ribonucleoprotein, PTB-binding 1
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Membrane Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly-pyrimidine Tract Binding Pre-mRNA Binding Poly(A) RNA Binding	Nucleotide Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Negative Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Muscle Cell Differentiation
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: APBB1 APP CALCOCO2 CASP3 ELAVL1 FUS HIST3H3 HMGA1 HMGA2 HNRNPAB HNRNPK HNRNPL IL7R NONO PCBP1 PCBP2 PCBP3 PRKACA QKI RAVER1 RAVER2 RBFOX2 RBM10 SFPQ SNRPA SRPK2 ZMYM2	4 interactors: ACTN1 ACTN2 PTBP1 VCL
Entrez ID		5725	125950
HPRD ID		02823	11484
Ensembl ID		ENSG00000011304	ENSG00000161847
Uniprot IDs		P26599	E9PAU2 Q8IY67
PDB IDs		1QM9 1SJQ 1SJR 2AD9 2ADB 2ADC 2EVZ 3ZZY 3ZZZ	3H2U 3H2V 3SMZ 3VF0
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Oncogene-induced Cell Senescence Positive Regulation Of Gene Expression Senescence-associated Heterochromatin Focus Assembly Positive Regulation Of Cellular Senescence Cellular Metabolic Process Positive Regulation Of Cell Aging Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Heterochromatin Assembly Cell Morphogenesis DNA Metabolic Process Cell Morphogenesis Involved In Differentiation Anatomical Structure Morphogenesis Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Heterochromatin Organization DNA Catabolic Process, Endonucleolytic Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Cycle Regulation Of Cell Cycle Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Stress Regulation Of Cellular Senescence Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway DNA Repair Chromatin Modification Cell Development Regulation Of Stem Cell Maintenance Response To Light Stimulus Positive Regulation Of Cell Death DNA Catabolic Process Cellular Senescence Chromosome Organization Extracellular Matrix Organization	Adherens Junction Assembly Platelet Degranulation Adherens Junction Organization Cell-matrix Adhesion Platelet Activation Cell Junction Assembly Cell-cell Junction Organization Cell-substrate Adhesion Focal Adhesion Assembly Exocytosis Blood Coagulation Hemostasis Cell-substrate Junction Assembly Secretion By Cell Apical Junction Assembly Regulation Of Body Fluid Levels Wound Healing Secretion Cell Activation Response To Wounding Cell-cell Junction Assembly Cell Adhesion Muscle Contraction Negative Regulation Of Cellular Component Movement Protein Localization To Tight Junction Muscle System Process Vesicle-mediated Transport Cell Projection Assembly Microspike Assembly Negative Regulation Of Protein Localization To Cell Surface Protein Localization To Cell Junction Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Cellular Component Assembly Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Establishment Of Localization In Cell Negative Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Potassium Ion Transmembrane Transport Actin Crosslink Formation Negative Regulation Of MRNA Splicing, Via Spliceosome Protein Localization To Cell Surface Regulation Of Protein Localization To Cell Surface Negative Regulation Of RNA Splicing Negative Regulation Of Potassium Ion Transport Cellular Localization Actin Filament-based Process Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Potassium Ion Transport Regulation Of Cellular Component Movement Muscle Filament Sliding
Tagcloud ?		aminobutyric ampa amphibians calmodulin camkiialpha clathrin demonstrations elongated exclude fiber gaba immunoblot intriguingly isoxazolepropionic lens lenses morphogenetic neurogenesis nonsense parallels polypyrimidine protrusions psd ptbp2 scaffold spacing spine splicing
Tagcloud (Difference) ?		aminobutyric ampa amphibians calmodulin camkiialpha clathrin demonstrations elongated exclude fiber gaba immunoblot intriguingly isoxazolepropionic lens lenses morphogenetic neurogenesis nonsense parallels polypyrimidine protrusions psd ptbp2 scaffold spacing spine splicing
Tagcloud (Intersection) ?