HNRNPAB and HOXC13

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		HNRNPAB	HOXC13
Gene Name		heterogeneous nuclear ribonucleoprotein A/B	homeobox C13
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Ribonucleoprotein Complex RNA Polymerase II Transcription Factor Complex	Nucleus
	Molecular Function	Nucleotide Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Binding MRNA Binding Sequence-specific DNA Binding Poly(A) RNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Protein Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Epithelial To Mesenchymal Transition Positive Regulation Of Transcription, DNA-templated	Hair Follicle Development Transcription, DNA-templated Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Nail Development Tongue Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs) ( 23648065) Biliary atresia ( 20460270) Waist-hip ratio ( 20935629)
Protein-Protein Interactions		16 interactors: ACTB DEDD2 ELAVL2 ERG HIST3H3 HMGA1 HOXC13 HOXD4 IL7R POLR3D PTBP1 PTBP2 RBFOX2 TP63 USP19 YWHAG	7 interactors: APEX1 ELF1 HNRNPAB HOXC9 MEIS1 NR2E3 RHOXF2
Entrez ID		3182	3229
HPRD ID		04067	00862
Ensembl ID		ENSG00000197451	ENSG00000123364
Uniprot IDs		Q99729	P31276
PDB IDs		3S7R
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of RNA Splicing Regulation Of Cellular Senescence Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Regulation Of Alternative MRNA Splicing, Via Spliceosome Homeostatic Process Negative Regulation Of Cellular Metabolic Process Chromatin Remodeling Positive Regulation Of Apoptotic Signaling Pathway Transcription, DNA-templated RNA Processing RNA Biosynthetic Process Epidermal Cell Division Ectoderm And Mesoderm Interaction Negative Regulation Of Potassium Ion Export Regulation Of MRNA Splicing, Via Spliceosome Cell Aging Regulation Of Heart Rate By Hormone Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development Interleukin-7-mediated Signaling Pathway Oncogene-induced Cell Senescence RNA Splicing Apoptotic Signaling Pathway Regulation Of MRNA Processing Cellular Metabolic Process Hair Follicle Development Hair Cycle Process Regulation Of Epidermal Cell Division Senescence-associated Heterochromatin Focus Assembly Regulation Of Cellular Process Hair Cycle MRNA Processing Positive Regulation Of Cellular Senescence Female Genitalia Morphogenesis Regulation Of Cell Differentiation Radial Glia Guided Migration Of Purkinje Cell Regulation Of Cellular Response To Hypoxia Regulation Of Definitive Erythrocyte Differentiation Cloacal Septation	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process RNA Metabolic Process Positive Regulation Of Rhodopsin Gene Expression Developmental Process Eye Morphogenesis Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Regulation Of Rhodopsin Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Organ Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Morphogenesis Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Smooth Muscle Cell Migration Camera-type Eye Development Megakaryocyte Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Immune System Process Nucleotide-excision Repair, DNA Gap Filling Biosynthetic Process DNA Demethylation Negative Regulation Of Biosynthetic Process Cellular Response To Organic Cyclic Compound Eye Development Negative Regulation Of T Cell Receptor Signaling Pathway Cellular Nitrogen Compound Metabolic Process Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Organ Development Positive Regulation Of Cell Cycle G1/S Phase Transition Nuclear DNA Replication
Tagcloud ?			chip deep dysregulated dysregulation h3k27me3 homeobox hoxb7 hoxd8 irx1 irx4 keratinocytes mark neoplastic okf6 oncomine polycomb prc prc2 repressive rnaseq scc six2 suz12 tert1r transcripts tshz3 tumorigenic
Tagcloud (Difference) ?			chip deep dysregulated dysregulation h3k27me3 homeobox hoxb7 hoxd8 irx1 irx4 keratinocytes mark neoplastic okf6 oncomine polycomb prc prc2 repressive rnaseq scc six2 suz12 tert1r transcripts tshz3 tumorigenic
Tagcloud (Intersection) ?