HNRNPAB and ELAVL2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		HNRNPAB	ELAVL2
Description		heterogeneous nuclear ribonucleoprotein A/B	ELAV like RNA binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Dendrite Protein-containing Complex MRNA Editing Complex Neuronal Ribonucleoprotein Granule RNA Polymerase II Transcription Regulator Complex Ribonucleoprotein Complex	Ribonucleoprotein Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Protein-containing Complex Binding Sequence-specific Double-stranded DNA Binding	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding
	Biological Process	Epithelial To Mesenchymal Transition Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process MRNA Modification Positive Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Regulation Of Cellular Localization Cellular Response To Amino Acid Stimulus Chromosomal 5-methylcytosine DNA Demethylation Pathway Regulation Of Intracellular MRNA Localization Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay	Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Immature fraction of reticulocytes ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Anxiety ( 33859377) Asthma ( 34103634 30929738) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Attending social / leisure activities ( 34054130) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically inactive individuals ( 28448500) Chronic obstructive pulmonary disease ( 30804561) Feeling guilty ( 29500382) Femur bone mineral density x serum urate levels interaction ( 34046847) Fulminant type 1 diabetes ( 30552108) General cognitive ability ( 29844566) Glomerular filtration rate change in heart transplantation ( 30160337) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Intelligence (MTAG) ( 29326435) Lung function (FEV1/FVC) ( 30061609) Neurociticism ( 29500382) Neuroticism ( 27067015 29255261 27089181) Physiological traits ( 31902109) Plasma t-tau levels ( 28100725) Remission after SSRI treatment in MDD or neuroticism ( 29559929) Schizophrenia ( 33169155) Sociability score ( 34054130)
Interacting Genes		21 interacting genes: ACTB CDC42 CEBPA DEDD2 ELAVL2 ERG H3-4 H3C1 HMGA1 HOXC13 HOXD4 IL7R OGT POLR3D PTBP1 PTBP2 PTEN RBFOX2 TP63 USP19 YWHAG	6 interacting genes: ELAVL3 ELAVL4 HNRNPAB HOXC9 NR2E3 RBFOX2
Entrez ID		3182	1993
HPRD ID		04067	03396
Ensembl ID		ENSG00000197451	ENSG00000107105
Uniprot IDs		Q99729	A0A0A0MRX1 Q12926
PDB IDs		3S7R
Enriched GO Terms of Interacting Partners?		Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Chromatin Binding Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Nucleoplasm Nucleus Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Morphogenesis Of A Polarized Epithelium DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Cell Differentiation Positive Regulation Of Stem Cell Population Maintenance Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Developmental Process DNA Binding Developmental Process Chromatin Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Stem Cell Population Maintenance Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process Macromolecule Metabolic Process Regulation Of Cell Differentiation Structural Constituent Of Chromatin Positive Regulation Of Signal Transduction Regulation Of Developmental Process Negative Regulation Of Developmental Process Dendritic Spine Morphogenesis Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Population Proliferation Positive Regulation Of Multicellular Organismal Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Polarized Epithelial Cell Differentiation Negative Regulation Of Cellular Senescence Regulation Of Cell Cycle	Negative Regulation Of MRNA Catabolic Process Regulation Of MRNA Metabolic Process Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Metabolic Process Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Ribonucleoprotein Complex MRNA 3'-UTR Binding Developmental Process MRNA 3'-UTR AU-rich Region Binding Nucleic Acid Binding Cellular Developmental Process MRNA Binding Negative Regulation Of RNA Metabolic Process RNA Metabolic Process MRNA Stabilization Cell Differentiation RNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Stabilization Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Pre-mRNA Intronic Pyrimidine-rich Binding Negative Regulation Of Catabolic Process Nuclear Receptor-mediated Signaling Pathway Cellular Response To Cell-matrix Adhesion MRNA Editing Complex Interleukin-11 Receptor Activity Interleukin-11 Binding Selenocysteine Insertion Sequence Binding Chromosomal 5-methylcytosine DNA Demethylation Pathway Hormone-mediated Signaling Pathway Positive Regulation Of 3'-UTR-mediated MRNA Stabilization Nucleic Acid Metabolic Process Regulation Of Intracellular MRNA Localization Neuronal Ribonucleoprotein Granule Positive Regulation Of Gene Expression Interleukin-11-mediated Signaling Pathway MRNA Metabolic Process Neuron Development Selenocysteine Incorporation Regulation Of MRNA Stability Regulation Of RNA Metabolic Process Regulation Of RNA Stability Megakaryocyte Differentiation Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Intracellular Receptor Signaling Pathway
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