HNRNPAB and POLR3D

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		HNRNPAB	POLR3D
Description		heterogeneous nuclear ribonucleoprotein A/B	RNA polymerase III subunit D
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Dendrite Protein-containing Complex MRNA Editing Complex Neuronal Ribonucleoprotein Granule RNA Polymerase II Transcription Regulator Complex Ribonucleoprotein Complex	DNA-directed RNA Polymerase Complex Nucleus Nucleoplasm RNA Polymerase III Complex Cytosol
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Protein-containing Complex Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Chromatin Binding
	Biological Process	Epithelial To Mesenchymal Transition Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process MRNA Modification Positive Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Regulation Of Cellular Localization Cellular Response To Amino Acid Stimulus Chromosomal 5-methylcytosine DNA Demethylation Pathway Regulation Of Intracellular MRNA Localization Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay	Immune System Process Transcription By RNA Polymerase III Positive Regulation Of Interferon-beta Production TRNA Transcription By RNA Polymerase III Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways			Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Immature fraction of reticulocytes ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Hypertriglyceridemia ( 23505323)
Interacting Genes		21 interacting genes: ACTB CDC42 CEBPA DEDD2 ELAVL2 ERG H3-4 H3C1 HMGA1 HOXC13 HOXD4 IL7R OGT POLR3D PTBP1 PTBP2 PTEN RBFOX2 TP63 USP19 YWHAG	15 interacting genes: APEX1 ATF3 HNRNPAB HOXA10 HOXC9 KLHL20 MAPK11 MSX2 NR2E3 OGT POLR3E RBFOX2 RHOXF2 TAB1 ZNF496
Entrez ID		3182	661
HPRD ID		04067	01755
Ensembl ID		ENSG00000197451	ENSG00000168495
Uniprot IDs		Q99729	P05423
PDB IDs		3S7R	7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59 7DN3 7DU2 7FJI 7FJJ 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS
Enriched GO Terms of Interacting Partners?		Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Chromatin Binding Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Nucleoplasm Nucleus Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Morphogenesis Of A Polarized Epithelium DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Cell Differentiation Positive Regulation Of Stem Cell Population Maintenance Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Developmental Process DNA Binding Developmental Process Chromatin Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Stem Cell Population Maintenance Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process Macromolecule Metabolic Process Regulation Of Cell Differentiation Structural Constituent Of Chromatin Positive Regulation Of Signal Transduction Regulation Of Developmental Process Negative Regulation Of Developmental Process Dendritic Spine Morphogenesis Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Population Proliferation Positive Regulation Of Multicellular Organismal Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Polarized Epithelial Cell Differentiation Negative Regulation Of Cellular Senescence Regulation Of Cell Cycle	Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Sequence-specific Double-stranded DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Nucleus Positive Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Metabolic Process DNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Proximal/distal Pattern Formation Anterior/posterior Pattern Specification Nucleoplasm Regulation Of Primary Metabolic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Developmental Process Pyroptotic Inflammatory Response Phosphodiesterase Activity, Acting On 3'-phosphoglycolate-terminated DNA Strands Class II DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Telomere Maintenance Via Base-excision Repair Positive Regulation Of TRAIL-activated Apoptotic Signaling Pathway Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Type II Interferon Binding Intracellular Receptor Signaling Pathway Transcription Regulator Complex DNA-(abasic Site) Binding Double-stranded DNA Exodeoxyribonuclease Activity Deoxyribonuclease (pyrimidine Dimer) Activity CHOP-ATF3 Complex Regionalization Protein K33-linked Ubiquitination Steroid Hormone Receptor Signaling Pathway
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