PTBP1 and SNRPA

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		PTBP1	SNRPA
Gene Name		polypyrimidine tract binding protein 1	small nuclear ribonucleoprotein polypeptide A
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Membrane Extracellular Vesicular Exosome	Nucleoplasm Spliceosomal Complex U1 SnRNP Nucleolus Cytoplasm
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly-pyrimidine Tract Binding Pre-mRNA Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding Protein Binding SnRNA Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Negative Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Muscle Cell Differentiation	MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: APBB1 APP CALCOCO2 CASP3 ELAVL1 FUS HIST3H3 HMGA1 HMGA2 HNRNPAB HNRNPK HNRNPL IL7R NONO PCBP1 PCBP2 PCBP3 PRKACA QKI RAVER1 RAVER2 RBFOX2 RBM10 SFPQ SNRPA SRPK2 ZMYM2	27 interactors: C19orf43 CDKN2A CIRBP ENOX2 GABPB1 HNRNPK IL7R LENG8 METTL13 MTUS2 NDUFAF3 PAPOLA PCBP1 PCBP2 PTBP1 PTBP2 QKI RBM3 RBM42 RBMX SFPQ SMAD5 SNRPA1 TRIM27 U2AF2 UBC WBP4
Entrez ID		5725	6626
HPRD ID		02823	01658
Ensembl ID		ENSG00000011304	ENSG00000077312
Uniprot IDs		P26599	B4DDC7 P09012
PDB IDs		1QM9 1SJQ 1SJR 2AD9 2ADB 2ADC 2EVZ 3ZZY 3ZZZ	1AUD 1CX0 1DRZ 1DZ5 1FHT 1M5K 1M5O 1M5P 1M5V 1NU4 1OIA 1SJ3 1SJ4 1SJF 1U6B 1URN 1VBX 1VBY 1VBZ 1VC0 1VC5 1VC6 1VC7 1ZZN 2A3J 2NZ4 2OIH 2OJ3 2U1A 3BO2 3BO3 3BO4 3CUL 3CUN 3EGZ 3G8S 3G8T 3G96 3G9C 3HHN 3IIN 3IRW 3IWN 3K0J 3L3C 3MUM 3MUR 3MUT 3MUV 3MXH 3P49 3PGW 3R1H 3R1L 3UCU 3UCZ 3UD3 3UD4 3UTR
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Oncogene-induced Cell Senescence Positive Regulation Of Gene Expression Senescence-associated Heterochromatin Focus Assembly Positive Regulation Of Cellular Senescence Cellular Metabolic Process Positive Regulation Of Cell Aging Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Heterochromatin Assembly Cell Morphogenesis DNA Metabolic Process Cell Morphogenesis Involved In Differentiation Anatomical Structure Morphogenesis Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Heterochromatin Organization DNA Catabolic Process, Endonucleolytic Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Cycle Regulation Of Cell Cycle Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Stress Regulation Of Cellular Senescence Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway DNA Repair Chromatin Modification Cell Development Regulation Of Stem Cell Maintenance Response To Light Stimulus Positive Regulation Of Cell Death DNA Catabolic Process Cellular Senescence Chromosome Organization Extracellular Matrix Organization	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process Negative Regulation Of RNA Splicing RNA Metabolic Process Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Regulation Of MRNA Processing Negative Regulation Of Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Macromolecule Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Regulation Of T Cell Differentiation In Thymus Negative Regulation Of Immune System Process Positive Regulation Of Cellular Metabolic Process Protein K63-linked Ubiquitination Positive Regulation Of RNA Splicing Negative Regulation Of Adaptive Immune Response Protein Polyubiquitination Termination Of RNA Polymerase II Transcription Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Type I Interferon Production Biosynthetic Process Ultradian Rhythm Negative Regulation Of Cytokine Production Cellular Metabolic Process Regulation Of MRNA Stability
Tagcloud ?		aminobutyric ampa amphibians calmodulin camkiialpha clathrin demonstrations elongated exclude fiber gaba immunoblot intriguingly isoxazolepropionic lens lenses morphogenetic neurogenesis nonsense parallels polypyrimidine protrusions psd ptbp2 scaffold spacing spine splicing	adh1c aldh6a1 aldob apom ces1 fads1 ftl glo1 hemopexin hnrpdl loc644587 lrrc28 methylglyoxal orosomucoid pabpc1 pla2g10 polr2k rpl14 rpl41 rpl8 rps17 rps24 rps5 srp9 ssh subtractive underexpressed zbtb11 zip14
Tagcloud (Difference) ?		aminobutyric ampa amphibians calmodulin camkiialpha clathrin demonstrations elongated exclude fiber gaba immunoblot intriguingly isoxazolepropionic lens lenses morphogenetic neurogenesis nonsense parallels polypyrimidine protrusions psd ptbp2 scaffold spacing spine splicing	adh1c aldh6a1 aldob apom ces1 fads1 ftl glo1 hemopexin hnrpdl loc644587 lrrc28 methylglyoxal orosomucoid pabpc1 pla2g10 polr2k rpl14 rpl41 rpl8 rps17 rps24 rps5 srp9 ssh subtractive underexpressed zbtb11 zip14
Tagcloud (Intersection) ?