Wiki-Pi
About
Search
People
Updates
Search
HMOX1 and KASH5
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
HMOX1
KASH5
Description
heme oxygenase 1
KASH domain containing 5
Image
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Nucleoplasm
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
Membrane
Perinuclear Region Of Cytoplasm
Chromosome, Telomeric Region
Lateral Element
Nucleus
Nuclear Envelope
Nuclear Outer Membrane
Chromosome
Membrane
Meiotic Nuclear Membrane Microtubule Tethering Complex
Meiotic Spindle Pole
Molecular Function
Heme Oxygenase (decyclizing) Activity
Structural Molecule Activity
Protein Binding
Oxidoreductase Activity
Enzyme Binding
Heme Binding
Identical Protein Binding
Protein Homodimerization Activity
Metal Ion Binding
Protein Binding
Identical Protein Binding
Dynein Complex Binding
Biological Process
Angiogenesis
Endothelial Cell Proliferation
Wound Healing Involved In Inflammatory Response
Negative Regulation Of Leukocyte Migration
Regulation Of Transcription By RNA Polymerase II
Heme Oxidation
Intracellular Iron Ion Homeostasis
Apoptotic Process
Response To Oxidative Stress
Smooth Muscle Hyperplasia
Macroautophagy
Positive Regulation Of Macroautophagy
Negative Regulation Of Macroautophagy
Positive Regulation Of Chemokine Production
Erythrocyte Homeostasis
Low-density Lipoprotein Particle Clearance
Cellular Response To Heat
Response To Nicotine
Intracellular Signal Transduction
Heme Catabolic Process
Heme Metabolic Process
Response To Hydrogen Peroxide
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Regulation Of Angiogenesis
Positive Regulation Of Angiogenesis
Positive Regulation Of Smooth Muscle Cell Proliferation
Negative Regulation Of Smooth Muscle Cell Proliferation
Multicellular Organismal-level Iron Ion Homeostasis
Cellular Response To Arsenic-containing Substance
Cellular Response To Cadmium Ion
Cellular Response To Cisplatin
Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of Ferroptosis
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Epithelial Cell Apoptotic Process
Positive Regulation Of Epithelial Cell Apoptotic Process
Double-strand Break Repair Via Homologous Recombination
Actin Filament Organization
Homologous Chromosome Pairing At Meiosis
Spermatogenesis
Telomere Localization
Meiotic Telomere Clustering
Oogenesis
Spindle Assembly
Meiotic Cell Cycle
Spindle Localization
Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation
Pathways
Heme degradation
Interleukin-4 and Interleukin-13 signaling
The NLRP3 inflammasome
Iron uptake and transport
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Purinergic signaling in leishmaniasis infection
Cytoprotection by HMOX1
Cytoprotection by HMOX1
Regulation of HMOX1 expression and activity
Heme signaling
NFE2L2 regulating anti-oxidant/detoxification enzymes
Drugs
NADH
Formic acid
Biliverdine IX Alpha
12-Phenylheme
2-Phenylheme
Verdoheme
Stannsoporfin
1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE
1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone
Diseases
GWAS
Hippocampal volume in mild cognitive impairment (
29274321
)
Obesity-related traits (
23251661
)
Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease (
29748315
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
45 interacting genes:
AKT1
AQP6
ARL13B
ASL
BLVRB
CD79A
COQ9
CPLX4
CPSF1
CRB3
CREB3
CYB561
CYBRD1
ELOVL4
ELOVL5
ELOVL6
ERGIC3
FAM174A
FAM209A
FAM210B
FKBP7
GPR152
JAGN1
KASH5
LMNA
MSMO1
NOS1
PDZK1IP1
POR
POT1
PTGER4
SAR1A
SEC11C
SLC10A6
SLC16A7
SMO
STX1A
TERF1
TLCD4
TM4SF19
TMEM14B
TMIE
TMX2
TUT1
USP7
112 interacting genes:
ABHD1
ADIPOQ
ANKRD46
ATF7
BAG5
BCL2L2
BET1
C14orf180
CCDC120
CCDC87
CDC73
CDKL3
CIB3
CLDN8
CMTM5
CRABP2
CTXN3
CWF19L2
CXCL16
CXCL9
CYBC1
DERL1
DNAJC30
EFNA5
EMD
FAM161A
FAM241B
FAM50B
FAM90A1
FATE1
FIS1
FRA10AC1
FTCD
FXYD3
GABARAPL2
GALNT2
GIMAP5
GOSR2
GPATCH4
GPR25
HMOX1
ITGAM
ITM2B
JAGN1
KDM1A
LARP1
LAT
LENG1
LHFPL5
LMNA
LRCH4
MALL
MARCHF2
MMP14
MOSPD3
MS4A1
MTX2
NRIP3
NSG1
NTAQ1
OLFM4
PDGFRA
PGAP2
PGRMC1
PIGU
PLP2
PLPP6
PPP1R18
RIPPLY2
RNF146
RSPH14
RSRC2
RTP2
SENP2
SERP2
SGTA
SHMT2
SLC30A2
SLC35B4
SLC41A1
SLC41A2
SLC5A4
SLC61A1
SLN
SMCO4
SNAP47
STBD1
STX12
STX5
TCF25
TMEM11
TMEM147
TMEM14C
TMEM19
TMEM41A
TMEM86A
TMPRSS4
TNF
TRAF3IP3
TRARG1
TSHZ3
TTC23
UPK1B
UPK2
VAMP1
VAMP2
VAMP4
VMA12
VTI1B
ZC2HC1C
ZFPL1
ZNF250
Entrez ID
3162
147872
HPRD ID
00782
08134
Ensembl ID
ENSG00000100292
ENSG00000161609
Uniprot IDs
P09601
Q6FH11
Q8N6L0
PDB IDs
1N3U
1N45
1NI6
1OYK
1OYL
1OZE
1OZL
1OZR
1OZW
1S13
1S8C
1T5P
1TWN
1TWR
1XJZ
1XK0
1XK1
1XK2
1XK3
3CZY
3HOK
3K4F
3TGM
4WD4
5BTQ
6EHA
6R2I
6WMF
Enriched GO Terms of Interacting Partners
?
Membrane
Fatty Acid Elongation, Monounsaturated Fatty Acid
Fatty Acid Elongase Activity
Fatty Acid Elongation, Polyunsaturated Fatty Acid
Fatty Acid Elongation, Saturated Fatty Acid
Very Long-chain Fatty Acid Biosynthetic Process
Fatty Acid Elongation
Endoplasmic Reticulum
Peptidyl-cysteine S-nitrosylase Activity
Ascorbate Homeostasis
Long-chain Fatty-acyl-CoA Biosynthetic Process
Nitric Oxide Biosynthetic Process
Transmembrane Monodehydroascorbate Reductase Activity
Long-chain Fatty-acyl-CoA Metabolic Process
Fatty-acyl-CoA Biosynthetic Process
Nitric Oxide Metabolic Process
Reactive Nitrogen Species Metabolic Process
Regulation Of Establishment Of Protein Localization To Telomere
Shelterin Complex
Very Long-chain Fatty Acid Metabolic Process
Endoplasmic Reticulum Membrane
Regulation Of Establishment Of Protein Localization To Chromosome
Unsaturated Fatty Acid Biosynthetic Process
Meiotic Telomere Clustering
Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation
Small Molecule Biosynthetic Process
Regulation Of Telomere Maintenance
Nuclear Telomere Cap Complex
Telomere Localization
Telomeric D-loop Disassembly
Identical Protein Binding
G-rich Strand Telomeric DNA Binding
Telomeric Loop Disassembly
Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway
Fatty Acid Derivative Biosynthetic Process
Telomere Capping
Interleukin-18-mediated Signaling Pathway
Amide Biosynthetic Process
FMN Binding
Left/right Axis Specification
Protein Binding
Carboxylic Acid Metabolic Process
Negative Regulation Of TORC1 Signaling
Organic Acid Metabolic Process
MRNA Cleavage And Polyadenylation Specificity Factor Complex
Mammary Gland Epithelial Cell Differentiation
Negative Regulation Of Release Of Cytochrome C From Mitochondria
Membrane
SNARE Complex
SNAP Receptor Activity
Protein Binding
Endoplasmic Reticulum Membrane
Vesicle Fusion
Organelle Fusion
Organelle Membrane Fusion
Membrane Fusion
Endoplasmic Reticulum
SNARE Binding
Membrane Organization
Localization Within Membrane
Vesicle Organization
Presynaptic Endosome Membrane
SNARE Complex Assembly
Mitochondrial Outer Membrane
Establishment Of Protein Localization To Membrane
Golgi Membrane
Endosome To Plasma Membrane Protein Transport
Positive Regulation Of Neutrophil Activation
Regulation Of Cellular Localization
Monoatomic Cation Transmembrane Transporter Activity
Vesicle-mediated Transport
Endomembrane System
Establishment Of Protein Localization To Plasma Membrane
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?