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DNTTIP2 and HIST4H4
Number of citations of the paper that reports this interaction (PMID
12786946
)
3
Data Source:
BioGRID
(pull down)
DNTTIP2
HIST4H4
Gene Name
deoxynucleotidyltransferase, terminal, interacting protein 2
histone cluster 4, H4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleolus
Nuclear Chromosome
Nucleosome
Extracellular Region
Nucleus
Nucleoplasm
Membrane
Protein Complex
Extracellular Vesicular Exosome
Molecular Function
Poly(A) RNA Binding
DNA Binding
Protein Binding
Histone Demethylase Activity (H4-K20 Specific)
Poly(A) RNA Binding
Protein Heterodimerization Activity
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Chromatin Silencing At RDNA
Mitotic Cell Cycle
Telomere Maintenance
Chromatin Organization
Nucleosome Assembly
DNA Replication-dependent Nucleosome Assembly
DNA Replication-independent Nucleosome Assembly
Gene Expression
DNA Methylation On Cytosine
CENP-A Containing Nucleosome Assembly
Histone H4-K20 Demethylation
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Gene Expression, Epigenetic
Pathways
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Mitotic Prophase
PKMTs methylate histone lysines
Regulatory RNA pathways
RNA Polymerase I Promoter Clearance
Deposition of new CENPA-containing nucleosomes at the centromere
HDMs demethylate histones
Cellular Senescence
Signaling by Wnt
HATs acetylate histones
M Phase
Amyloids
NoRC negatively regulates rRNA expression
Packaging Of Telomere Ends
Telomere Maintenance
Nucleosome assembly
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
DNA methylation
Transcriptional regulation by small RNAs
Meiotic recombination
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
HDACs deacetylate histones
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
RNA Polymerase I Transcription
formation of the beta-catenin:TCF transactivating complex
Meiotic synapsis
Epigenetic regulation of gene expression
Senescence-Associated Secretory Phenotype (SASP)
Negative epigenetic regulation of rRNA expression
PRC2 methylates histones and DNA
Cell Cycle, Mitotic
RMTs methylate histone arginines
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
TCF dependent signaling in response to WNT
RNA Polymerase I Promoter Opening
SIRT1 negatively regulates rRNA Expression
Signaling by WNT in cancer
Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Pubertal anthropometrics (
23449627
)
Protein-Protein Interactions
11 interactors:
DNTT
ESR1
ESR2
HIST1H2BA
HIST2H3A
HIST3H2A
HIST4H4
PCNA
PPARG
RXRA
SPP1
52 interactors:
ANP32A
ARID4A
ASF1A
ASF1B
BRD2
BRD4
BRD7
CBX5
CDY1
COPRS
CREBBP
DAXX
DNTTIP2
EP300
GADD45A
HAT1
HDAC6
HDAC8
HDAC9
ING1
ING2
KAT2A
KAT2B
KAT6A
L3MBTL1
LRWD1
MSL3
NCOA2
NCOA3
NOC2L
NSD1
ORC2
ORC3
ORC4
ORC5
PRMT1
PRMT6
RAG1
RPS6KA5
SAP30
SET
SETD8
SETDB1
SIAH1
SMARCA5
TAF1A
TP53BP1
UBE2I
UCHL5
USP16
VHL
WDR5
Entrez ID
30836
121504
HPRD ID
09994
13662
Ensembl ID
ENSG00000197837
Uniprot IDs
Q5QJE6
B2R4R0
P62805
PDB IDs
2BQZ
2CV5
2KWN
2KWO
2LVM
2QQS
2RNY
2RS9
3A6N
3AFA
3AN2
3AV1
3AV2
3AYW
3AZE
3AZF
3AZG
3AZH
3AZI
3AZJ
3AZK
3AZL
3AZM
3AZN
3CFS
3CFV
3F9W
3F9X
3F9Y
3F9Z
3NQJ
3NQU
3O36
3QZS
3QZT
3QZV
3R45
3UVW
3UVX
3UVY
3UW9
3W96
3W97
3W98
3W99
4GQB
4H9N
4H9O
4H9P
4H9Q
4H9R
4H9S
4HGA
Enriched GO Terms of Interacting Partners
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Steroid Hormone Mediated Signaling Pathway
Hormone-mediated Signaling Pathway
Developmental Process Involved In Reproduction
Nucleobase-containing Compound Metabolic Process
Response To Lipid
Transcription Initiation From RNA Polymerase II Promoter
Cellular Response To Steroid Hormone Stimulus
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Response To Steroid Hormone
Intracellular Receptor Signaling Pathway
Reproductive Structure Development
Cellular Nitrogen Compound Metabolic Process
Reproductive System Development
Epithelial Cell Differentiation
Peroxisome Proliferator Activated Receptor Signaling Pathway
DNA-templated Transcription, Initiation
DNA Metabolic Process
Prostate Gland Development
Nitrogen Compound Metabolic Process
Single Organism Reproductive Process
Regulation Of Branching Involved In Prostate Gland Morphogenesis
Maternal Process Involved In Female Pregnancy
DNA Modification
Reproductive Process
Negative Regulation Of Gene Expression
DNA Methylation On Cytosine
Vagina Development
Multicellular Organismal Reproductive Process
Uterus Development
Multicellular Organism Reproduction
Nucleosome Disassembly
Cellular Response To Organic Cyclic Compound
Chromatin Silencing At RDNA
Response To Organic Cyclic Compound
Cellular Response To Lipid
Intracellular Estrogen Receptor Signaling Pathway
Epithelial Cell Differentiation Involved In Prostate Gland Development
Nucleosome Organization
Response To Hormone
Female Genitalia Development
Negative Regulation Of Cell Growth
Chromatin Assembly Or Disassembly
Tissue Development
Chromosome Organization
Reproduction
Epithelium Development
Chromatin Remodeling
Negative Regulation Of Transcription, DNA-templated
Placenta Development
Chromatin Organization
Chromatin Modification
Chromosome Organization
Histone Modification
Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Peptidyl-lysine Modification
Regulation Of RNA Metabolic Process
Cellular Macromolecule Biosynthetic Process
Organelle Organization
Macromolecule Biosynthetic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Gene Expression
Nitrogen Compound Metabolic Process
Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Peptidyl-amino Acid Modification
Gene Expression
RNA Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Histone Acetylation
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Protein Acetylation
Cellular Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Protein Modification Process
Chromatin Assembly Or Disassembly
Positive Regulation Of Macromolecule Biosynthetic Process
Chromatin Assembly
Positive Regulation Of Transcription, DNA-templated
Histone H3-K9 Modification
Histone Methylation
Positive Regulation Of Gene Expression
Cell Cycle
Nucleosome Assembly
DNA Packaging
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Tagcloud (Intersection)
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