DNTTIP2 and TULP3

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		DNTTIP2	TULP3
Description		deoxynucleotidyltransferase terminal interacting protein 2	TUB like protein 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Small-subunit Processome	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Cilium Axoneme Membrane Ciliary Basal Body Cell Projection Ciliary Base 9+0 Non-motile Cilium
	Molecular Function	RNA Binding Protein Binding	G Protein-coupled Receptor Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Enzyme Binding Phosphatidylinositol Binding Protein-containing Complex Binding Intraciliary Transport Particle A Binding
	Biological Process	RNA Processing Ribosomal Small Subunit Biogenesis	Neural Tube Formation Neural Tube Closure Regulation Of DNA-templated Transcription G Protein-coupled Receptor Signaling Pathway Smoothened Signaling Pathway Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Smoothened Signaling Pathway Anterior/posterior Pattern Specification Dorsal/ventral Neural Tube Patterning Neural Tube Development Central Nervous System Neuron Differentiation Embryonic Camera-type Eye Development Embryonic Digit Morphogenesis Negative Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Limb Development Bone Development Bronchus Morphogenesis Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Protein Localization To Cilium Ganglion Development
Pathways			Hedgehog 'off' state
Drugs
Diseases
GWAS		Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Serum polyunsaturated fatty acid concentration x sex interaction in metabolic syndrome ( 31991592)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		18 interacting genes: CAVIN1 CEP70 DNTT ESR1 ESR2 H2AC25 H2BC1 H3C15 H4C16 PCNA PICK1 PPARG RBPMS RNF10 RNF8 RXRA SPP1 TULP3	61 interacting genes: ACTN2 AKAP9 ANKRD1 ARHGAP21 ARMCX2 ATP2A1 BACH2 BOC BRMS1L BTBD1 CCNB1 CHD2 CLIP4 DNTTIP2 DROSHA DST ESRRG GPATCH2L GSE1 HSF2BP KIF3A KLF10 KRTAP10-1 KRTAP10-5 KRTAP10-7 MAGEA6 MAP3K5 MBTD1 MGA MORF4L1 MYBPC2 MYH3 MYH7 MYO18B NCOR1 NFE2L1 NOSTRIN NRIP1 PAF1 PCGF6 PDE4DIP PHAX PSTPIP1 RCOR3 RIOK3 RNF10 ROPN1 RYR1 SLAIN2 SPTB SRP72 TNNT1 TNNT3 WNK1 ZFAT ZNF160 ZNF462 ZNF619 ZNF793 ZNF835 ZSCAN23
Entrez ID		30836	7289
HPRD ID		09994	05292
Ensembl ID		ENSG00000067334	ENSG00000078246
Uniprot IDs		Q5QJE6	B7Z1E7 O75386
PDB IDs		7MQ8 7MQ9 7MQA	8FH3
Enriched GO Terms of Interacting Partners?		Nuclear Receptor Activity DNA Binding Enzyme Binding Nuclear Steroid Receptor Activity Structural Constituent Of Chromatin Nuclear Receptor-mediated Signaling Pathway Nuclear Estrogen Receptor Activity DNA Binding Domain Binding Nucleosome Nucleosome Organization Transcription Coregulator Binding Positive Regulation Of Lipoprotein Transport Nucleoplasm Chromatin Organization Hormone-mediated Signaling Pathway LBD Domain Binding Identical Protein Binding Chromosome, Telomeric Region Chromatin Remodeling Protein-DNA Complex Assembly Chromatin Regulation Of DNA-templated Transcription Estrogen Response Element Binding Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Regulation Of RNA Biosynthetic Process Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Intracellular Receptor Signaling Pathway Positive Regulation Of Lipid Transport Chromatin Binding Response To Lipid Regulation Of RNA Metabolic Process Nucleobase-containing Compound Biosynthetic Process Negative Regulation Of DNA-templated Transcription Protein Localization To Chromosome Monocyte Differentiation Sperm DNA Condensation Nucleosome Disassembly Nucleosome Assembly Response To Estradiol Negative Regulation Of RNA Biosynthetic Process Protein-DNA Complex Disassembly Estrogen Receptor Signaling Pathway Retinoic Acid Receptor Signaling Pathway Negative Regulation Of Transcription By RNA Polymerase II Androgen Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process	Sarcomere Organization Actomyosin Structure Organization Cytoskeleton Organization Regulation Of RNA Metabolic Process Myosin Filament Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Skeletal Muscle Contraction Actin Filament-based Process H Zone Striated Muscle Contraction Myofibril Actin Cytoskeleton Organization Sarcomere Actin Binding Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Microtubule Plus-end Myosin II Complex Organelle Organization I Band Histone Deacetylase Binding Z Disc Extrinsic Component Of Postsynaptic Density Membrane Striated Muscle Cell Development Regulation Of Macromolecule Biosynthetic Process Microtubule Cytoskeleton Organization Positive Regulation Of Microtubule Polymerization DNA Binding Transition Between Fast And Slow Fiber Muscle System Process Negative Regulation Of RNA Metabolic Process Troponin Complex Cardiac Muscle Cell Development Muscle Cell Development Nucleus Positive Regulation Of RNA Metabolic Process Histone Deacetylase Complex Regulation Of Primary Metabolic Process Cardiac Cell Development Microtubule-based Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Skeletal Muscle Adaptation Myosin Complex Actin Filament Binding
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