DNTTIP2 and CAVIN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DNTTIP2	CAVIN1
Description		deoxynucleotidyltransferase terminal interacting protein 2	caveolae associated protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Small-subunit Processome	Nucleus Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Plasma Membrane Caveola Membrane Protein-containing Complex Membrane Raft
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding RRNA Binding RRNA Primary Transcript Binding Identical Protein Binding
	Biological Process	RNA Processing Ribosomal Small Subunit Biogenesis	DNA-templated Transcription Termination Transcription Initiation At RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription RRNA Transcription Protein Secretion Positive Regulation Of Cell Motility
Pathways			RNA Polymerase I Transcription Termination RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle
Drugs
Diseases
GWAS		Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Serum polyunsaturated fatty acid concentration x sex interaction in metabolic syndrome ( 31991592)
Interacting Genes		18 interacting genes: CAVIN1 CEP70 DNTT ESR1 ESR2 H2AC25 H2BC1 H3C15 H4C16 PCNA PICK1 PPARG RBPMS RNF10 RNF8 RXRA SPP1 TULP3	24 interacting genes: CDC37 CDCA7L DNTTIP2 DUX4 ERCC6 INO80B KAT5 MECOM MRPL45 NKX2-1 OGT SOCS3 SPANXN3 TNFAIP8L1 TSGA10IP TTC5 TTF1 UBC UBE2O YAF2 ZCCHC10 ZFP1 ZNF148 ZSCAN21
Entrez ID		30836	284119
HPRD ID		09994	04433
Ensembl ID		ENSG00000067334	ENSG00000177469
Uniprot IDs		Q5QJE6	Q6NZI2
PDB IDs		7MQ8 7MQ9 7MQA	9EG6 9EGN 9EIU
Enriched GO Terms of Interacting Partners?		Nuclear Receptor Activity DNA Binding Enzyme Binding Nuclear Steroid Receptor Activity Structural Constituent Of Chromatin Nuclear Receptor-mediated Signaling Pathway Nuclear Estrogen Receptor Activity DNA Binding Domain Binding Nucleosome Nucleosome Organization Transcription Coregulator Binding Positive Regulation Of Lipoprotein Transport Nucleoplasm Chromatin Organization Hormone-mediated Signaling Pathway LBD Domain Binding Identical Protein Binding Chromosome, Telomeric Region Chromatin Remodeling Protein-DNA Complex Assembly Chromatin Regulation Of DNA-templated Transcription Estrogen Response Element Binding Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Regulation Of RNA Biosynthetic Process Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Intracellular Receptor Signaling Pathway Positive Regulation Of Lipid Transport Chromatin Binding Response To Lipid Regulation Of RNA Metabolic Process Nucleobase-containing Compound Biosynthetic Process Negative Regulation Of DNA-templated Transcription Protein Localization To Chromosome Monocyte Differentiation Sperm DNA Condensation Nucleosome Disassembly Nucleosome Assembly Response To Estradiol Negative Regulation Of RNA Biosynthetic Process Protein-DNA Complex Disassembly Estrogen Receptor Signaling Pathway Retinoic Acid Receptor Signaling Pathway Negative Regulation Of Transcription By RNA Polymerase II Androgen Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process	Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Nucleoplasm Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleolus Regulation Of RNA Metabolic Process DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Circadian Rhythm Positive Regulation Of Biosynthetic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone Acetyltransferase Complex Regulation Of Primary Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of DNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Chromatin Organization Positive Regulation Of DNA Repair Positive Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Histone H2AK5 Acetyltransferase Activity Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Chromatin Remodeling Regulation Of Macromolecule Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
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