HUNK and ATP5F1B

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		HUNK	ATP5F1B
Description		hormonally up-regulated Neu-associated kinase	ATP synthase F1 subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Plasma Membrane Cell Surface Membrane Proton-transporting Two-sector ATPase Complex Mitochondrial Membrane Mitochondrial Nucleoid Proton-transporting ATP Synthase Complex Extracellular Exosome Transmembrane Transporter Complex
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	Nucleotide Binding Protein Binding ATP Binding MHC Class I Protein Binding Angiostatin Binding Metal Ion Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Signal Transduction Intracellular Signal Transduction	Angiogenesis Osteoblast Differentiation Generation Of Precursor Metabolites And Energy Lipid Metabolic Process ATP Biosynthetic Process Monoatomic Ion Transport Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Positive Regulation Of Blood Vessel Endothelial Cell Migration ATP Metabolic Process Regulation Of Intracellular PH Cellular Response To Interleukin-7 Proton Transmembrane Transport
Pathways			Mitochondrial protein import Mitochondrial protein import Formation of ATP by chemiosmotic coupling Transcriptional activation of mitochondrial biogenesis Cristae formation Mitochondrial protein degradation
Drugs			Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE Phenethyl Isothiocyanate
Diseases
GWAS		Crohn's disease ( 32581322) Joint damage progression in ACPA-negative rheumatoid arthritis ( 26077402) LDL cholesterol levels in HIV infection ( 33109212) Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309) Type 2 diabetes ( 21490949) Vitiligo ( 19890347)
Interacting Genes		92 interacting genes: AARS1 ABLIM1 ACTR8 AGAP3 AIP AKAP8L AKR1C3 ALAD ANXA7 APBA2 APPL2 ARMCX4 ASCL1 ASPA ATP5F1B BIN1 CAMK1 CCAR1 CLU COG2 COPA COPS4 COPS5 CTDSP1 CTR9 CXXC5 DIS3L DLAT DLST DNAJA1 DST EEF1A2 EFNA1 EIF4G1 EPRS1 GEN1 HEATR6 HEY1 IFT81 IFT88 KDM6A KIF3A LIMK1 LNX1 LRSAM1 LURAP1 MAGED1 MBD1 MCHR1 MGAT5B MOAP1 MORF4L2 MTMR10 MYCBP2 N4BP2L2 NAPA NEUROD2 OLR1 PICK1 PITHD1 PPP1R16B PTPRA PTPRD RAB5B RABEP1 SH2B1 SLC6A1 SMARCE1 SMYD2 SNRNP48 SNRNP70 SORBS1 SPARCL1 STMN1 STUB1 TAF1 TOMM6 TRIM68 TTC28 UBE2O USP8 VCPIP1 VPS35L VSNL1 ZBTB44 ZNF197 ZNF292 ZNF343 ZNF655 ZNF662 ZNF76 ZNF793	29 interacting genes: ANXA7 APOA1 ATP5F1C ATPAF1 ATPAF2 BYSL CDK4 CDKN1A DOP1B DSCAM EIF4ENIF1 FANCA GRB7 HMOX2 HUNK LCOR LNX2 OGT PIN1 PLG PSME3 RPP14 SMN1 SUMO4 TERT TK1 TRIM55 TRIM63 YWHAG
Entrez ID		30811	506
HPRD ID		09410	00044
Ensembl ID		ENSG00000142149	ENSG00000110955
Uniprot IDs		P57058	P06576 V9HW31
PDB IDs			8H9E 8H9I 8H9L 8H9P 8H9S 8H9T 8H9U 8H9V 8KI3
Enriched GO Terms of Interacting Partners?		Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Metal Ion Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Protein Catabolic Process Regulation Of Cellular Component Organization Negative Regulation Of Protein Metabolic Process Regulation Of DNA-templated Transcription Positive Regulation Of Cellular Component Organization Positive Regulation Of Amyloid Fibril Formation Protein Modification By Small Protein Conjugation Regulation Of RNA Biosynthetic Process DeNEDDylase Activity	Mitochondrial Proton-transporting ATP Synthase Complex Assembly Proton-transporting ATP Synthase Complex Assembly
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