ATP5B and ATPAF1

Number of citations of the paper that reports this interaction (PMID 12206899)
9

Data Source:
HPRD (two hybrid, in vitro)

		ATP5B	ATPAF1
Gene Name		ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	ATP synthase mitochondrial F1 complex assembly factor 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Proton-transporting ATP Synthase, Catalytic Core Mitochondrial Matrix Plasma Membrane Cell Surface Membrane Mitochondrial Membrane Mitochondrial Nucleoid Extracellular Vesicular Exosome	Mitochondrion
	Molecular Function	Transporter Activity Protein Binding ATP Binding ATPase Activity Transmembrane Transporter Activity MHC Class I Protein Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding
	Biological Process	Angiogenesis Osteoblast Differentiation Generation Of Precursor Metabolites And Energy Lipid Metabolic Process ATP Biosynthetic Process Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Organelle Organization Mitochondrion Organization ATP Hydrolysis Coupled Proton Transport Proton Transport Respiratory Electron Transport Chain Mitochondrial ATP Synthesis Coupled Proton Transport Cellular Metabolic Process Small Molecule Metabolic Process Regulation Of Intracellular PH	Protein Complex Assembly
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Organelle biogenesis and maintenance Mitochondrial protein import Transcriptional activation of mitochondrial biogenesis The citric acid (TCA) cycle and respiratory electron transport Formation of ATP by chemiosmotic coupling Mitochondrial biogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ANXA7 APOA1 ATP5A1 ATP5C1 ATPAF1 ATPAF2 CDK4 CDKN1A FANCA GRB7 HMOX2 PIN1 PLG PSME3 RPP14 SMN1 SUMO4 TERT TK1 TRIM55 TRIM63 YWHAG	2 interactors: ATP5A1 ATP5B
Entrez ID		506	64756
HPRD ID		00044	12332
Ensembl ID		ENSG00000110955	ENSG00000123472
Uniprot IDs		P06576	A8MRA7 I3L448 Q5TC12
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Organic Cyclic Compound Organ Regeneration Response To Steroid Hormone Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cell Cycle Arrest Mitochondrial ATP Synthesis Coupled Proton Transport Nucleoside Monophosphate Biosynthetic Process Response To Hormone Cellular Component Assembly Response To Organic Substance Response To Hyperoxia Response To Abiotic Stimulus Response To Glucocorticoid G1/S Transition Of Mitotic Cell Cycle Response To Stress ATP Synthesis Coupled Proton Transport Response To Corticosteroid Regulation Of Mitotic Cell Cycle Response To Toxic Substance Hemostasis ATP Biosynthetic Process Posttranscriptional Regulation Of Gene Expression Response To Lipid Regulation Of Cell Cycle Process Cellular Metabolic Process Negative Regulation Of Cell Adhesion Molecule Production Fetal Process Involved In Parturition Negative Regulation Of Production Of SiRNA Involved In RNA Interference Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Response To Stimulus Regulation Of Cell Cycle Phase Transition DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Regulation Of Cellular Protein Metabolic Process Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Positive Regulation Of Transferase Activity Positive Regulation Of Fibroblast Proliferation Regulation Of Body Fluid Levels Negative Regulation Of RNA Interference Skeletal Muscle Cell Proliferation Negative Regulation Of Interleukin-1 Beta Secretion Transcription, RNA-templated Platelet Degranulation Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Cell Aging	Mitochondrial ATP Synthesis Coupled Proton Transport ATP Synthesis Coupled Proton Transport ATP Biosynthetic Process ATP Hydrolysis Coupled Proton Transport Purine Ribonucleoside Monophosphate Biosynthetic Process Nucleoside Triphosphate Biosynthetic Process Ribonucleoside Monophosphate Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process Respiratory Electron Transport Chain Electron Transport Chain ATP Metabolic Process Mitochondrial Transport Cellular Respiration Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Hydrogen Ion Transmembrane Transport Proton Transport Purine Nucleoside Metabolic Process Ribonucleotide Metabolic Process Nucleoside Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Nucleotide Biosynthetic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Generation Of Precursor Metabolites And Energy Nucleotide Metabolic Process Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Nucleobase-containing Small Molecule Metabolic Process Monovalent Inorganic Cation Transport Cation Transmembrane Transport Organophosphate Metabolic Process Cation Transport Negative Regulation Of Endothelial Cell Proliferation Lipid Metabolic Process Substrate-dependent Cell Migration Ion Transmembrane Transport Regulation Of Intracellular PH Regulation Of Cellular PH Oxidation-reduction Process Intracellular Transport Transmembrane Transport Ion Transport Regulation Of PH Regulation Of Endothelial Cell Proliferation Establishment Of Localization In Cell Small Molecule Metabolic Process Cellular Localization Negative Regulation Of Epithelial Cell Proliferation Osteoblast Differentiation Phosphate-containing Compound Metabolic Process
Tagcloud ?		1p13 1p36 5x10 6q16 7p14 8q21 affecting ajap1 apoa1bp c7orf10 candidate fhl5 fut9 loci locus matched meta migraine mmp16 near poorly stat6 subgroup susceptibility tbc1d7 trait tspan2 understood wide
Tagcloud (Difference) ?		1p13 1p36 5x10 6q16 7p14 8q21 affecting ajap1 apoa1bp c7orf10 candidate fhl5 fut9 loci locus matched meta migraine mmp16 near poorly stat6 subgroup susceptibility tbc1d7 trait tspan2 understood wide
Tagcloud (Intersection) ?